Endobloc 10 Tablet
By Endobloc
Rx
10 Tablet in a Strip

Composition
Ambrisentan(10mg)

Manufacturer - Cipla Ltd
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Expires on or after
July, 2026
About Endobloc 10 Tablet
Endobloc 10 Tablet is a prescription medicine used to treat pulmonary arterial hypertension, which is high pressure in the blood vessels carrying blood from the heart to the lungs. This condition can impact your quality of life, exercise ability, and delay disease progression. It is recommended to take Endobloc 10 Tablet as per the doctor’s advice, with or without food. If a dose is missed, it should be taken as soon as remembered.
Common side effects of Endobloc 10 Tablet include peripheral edema, nasal congestion, sinusitis, and flushing. If these side effects persist or bother you, inform your doctor. Some individuals may experience dizziness, so caution is advised when performing tasks that require mental focus. Prior to starting treatment, inform your doctor about any medications you are taking for other health conditions. Patients with liver or kidney disease should be cautious and follow up regularly as directed by the doctor.
Endobloc 10 Tablet belongs to the class of anti-hypertensive drugs and contains Ambrisentan, which is an endothelin receptor blocker. Ambrisentan works by inhibiting the action of endothelin, a natural substance that constricts blood vessels and raises blood pressure. By widening the constricted pulmonary arteries and increasing blood supply to the lungs, Endobloc 10 Tablet helps lower blood pressure in individuals with pulmonary arterial hypertension.
In some cases, side effects of Endobloc 10 Tablet may include headache, dizziness, palpitations, breathlessness, runny nose, nausea, diarrhea, and fatigue. The occurrence and severity of these side effects can vary. It is important to consult with your doctor if you experience side effects that are difficult to manage. Before starting Endobloc 10 Tablet, inform your doctor about any allergies, medications, or health conditions you have, including low blood pressure, lung, heart, kidney, or liver issues.
If you are pregnant, breastfeeding, or have anaemia, consult your doctor before taking Endobloc 10 Tablet. It is advised not to stop taking the medication without consulting your doctor, as it could worsen your condition and increase the risk of future heart problems. Additionally, avoid consuming alcohol while on Endobloc 10 Tablet, as it may heighten the risk of low blood pressure.
Benefits
Endobloc 10 Tablet is a powerful medication specifically designed to address the symptoms and complications of Pulmonary Arterial Hypertension (PAH). PAH can severely impact daily life, causing shortness of breath, fatigue, chest pain, dizziness, and swelling in the ankles and legs. These symptoms are a result of the thickening of the arteries supplying the lungs, making it difficult for blood to flow through smoothly.
One of the key benefits of Endobloc 10 Tablet is its ability to relax the blood vessels, thereby reducing the blood pressure within the arteries of the lungs. By containing the active ingredient 'Ambrisentan,' which is an endothelin receptor blocker, this medication effectively inhibits the action of endothelin - a natural substance that causes blood vessels to constrict and blood pressure to rise. In individuals with PAH, the pulmonary arteries become narrow, forcing the heart to work harder to pump blood efficiently. Endobloc 10 Tablet acts by widening these constricted arteries, easing the workload on the heart, and ultimately lowering blood pressure.
By taking Endobloc 10 Tablet as prescribed, patients can experience significant improvements in their daily activities. They may find it easier to carry out tasks, feel less fatigued, and experience less dizziness. Ultimately, the medication aims to enhance the quality of life for individuals living with PAH by improving blood flow and reducing the strain on the heart. With Endobloc 10 Tablet, managing PAH becomes more manageable, allowing patients to lead a more comfortable and active lifestyle.
How to use the Endobloc 10 Tablet
To use Endobloc 10 Tablet, follow your doctor's instructions on dosage and duration. Swallow the tablet whole with a glass of water. It is important not to crush, chew, or break the tablet. Endobloc 10 Tablet can be taken with or without food, but it is recommended to take it at the same time each day for best results. Make sure to take it regularly as prescribed by your doctor.
Uses of Endobloc 10 Tablet
Endobloc 10 Tablet is primarily prescribed for the treatment of Pulmonary Arterial Hypertension (PAH). PAH is a condition characterized by high blood pressure in the arteries of the lungs, which can lead to symptoms such as shortness of breath, chest pain, and fatigue. Endobloc 10 Tablet works by relaxing the blood vessels in the lungs, thereby reducing the strain on the heart and improving blood flow. This medication is an essential part of managing PAH and can help improve exercise capacity and quality of life in individuals with this condition. It is important to follow the prescribed dosage and schedule as directed by a healthcare provider to ensure optimal effectiveness of Endobloc 10 Tablet in treating PAH.
What conditions Endobloc 10 Tablet treats?
Hypertension, a condition characterized by persistently elevated blood pressure in the arteries, is a known risk factor for cardiovascular diseases. Causes include obesity, diabetes, smoking, high salt intake, stress, physical inactivity, and aging. Blood pressure is measured as a ratio of systolic (when the heart pumps) to diastolic (during heart's resting stage) pressure. An ideal range is 90/60 mmHg to 120/80 mmHg. Pulmonary Arterial Hypertension is high blood pressure in the pulmonary arteries, leading to symptoms like shortness of breath, dizziness, and chest pressure.
Should you consult a doctor?
If you experience persistent side effects such as peripheral edema, nasal congestion, sinusitis, or flushing while taking Endobloc 10 Tablet, it is important to seek medical advice. Additionally, if you feel dizzy after taking the medication, avoid activities that require mental alertness like driving, and consult your doctor. Inform your doctor about any other medications you are taking for other health issues before starting Endobloc 10 Tablet. Patients with liver or kidney conditions should be cautious and follow up with their doctor regularly. If side effects worsen, do not hesitate to consult your healthcare provider. Remember to take Endobloc 10 Tablet as prescribed by your doctor for effective management of pulmonary arterial hypertension.
Side effects of Endobloc 10 Tablet
When taking Endobloc 10 Tablet, some side effects may occur, but most of them are not serious and will go away as your body gets used to the medication. However, if these side effects persist or you are concerned about them, it is essential to consult your doctor. Common side effects of Endobloc 10 Tablet may include peripheral edema, which is swelling caused by fluid retention in the body. You may also experience nasal congestion, sinus inflammation, and flushing, characterized by a sensation of warmth in the face, ears, neck, and trunk. Other potential side effects that may occur include headaches, dizziness, swelling in the hands, legs, ankles, or feet, palpitations, breathlessness, chest pain or discomfort, stuffy nose, sinus pain, skin redness or flushing, nausea, diarrhea, fatigue, and rash. It is important to monitor these side effects and seek medical advice if needed.
Safety advice

liver
When using Endobloc 10 Tablet, it's important to be cautious if you have liver disease. Patients with liver issues may require a dosage adjustment when taking Endobloc 10 Tablet. It is recommended to consult your doctor for proper guidance regarding the use of this medication in such cases.

kidney
Endobloc 10 Tablet needs cautious use in severe kidney disease. Dose adjustment may be necessary. Limited data is available. No adjustment is needed for mild to moderate kidney issues. Please consult your doctor.

alcohol
Consult your doctor when consuming alcohol with Endobloc 10 Tablet.

driving
When taking Endobloc 10 Tablet, be cautious while driving. It may lead to dizziness or weakness from low blood pressure. Avoid driving if you experience these symptoms.

pregnancy
Endobloc 10 Tablet is not safe to use during pregnancy. Consult your doctor as research on pregnant women and animals has demonstrated harmful effects on the developing baby.

breastfeeding
It is better to consult your doctor before using Endobloc 10 Tablet.
Consumption warning before consuming Endobloc 10 Tablet
Before consuming Endobloc 10 Tablet, it is important to consider certain factors. If you have a history of heart failure, liver or kidney diseases, lung conditions such as pulmonary fibrosis, anaemia, oedema (fluid retention), or hypotension (low blood pressure), it is crucial to inform your healthcare provider before starting this medication. Endobloc 10 Tablet is not recommended during pregnancy as it can have harmful effects on the developing foetus. If you are a breastfeeding mother, consulting your doctor before using this medication is advisable. It is essential to complete the prescribed course as directed by your doctor, even if you start feeling better, to prevent the recurrence of symptoms. Due to potential side effects like dizziness and weakness, which can affect concentration and driving ability, it is recommended to avoid driving or operating machinery while taking Endobloc 10 Tablet. Additionally, consumption of alcohol should be avoided as it may increase the risk of low blood pressure. This medication is not suitable for individuals under 18 years of age.
What if you forgot to take Endobloc 10 Tablet?
If you forget to take a dose of Endobloc 10 Tablet, take it as soon as you remember. If it's close to the time for your next dose, skip the missed one and stick to your usual schedule. Avoid taking a double dose to make up for the missed one.
Additional Information
Habit Forming | No |
Chemical Class | Diphenylmethane Derivative |
Therapeutic Class | - |
Action Class | Endothelin receptor blocker |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹3142.23
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Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024