Endace 160 Tablet
By Endace
Rx
10 Tablet in a Strip

Composition
Megestrol(160mg)

Manufacturer - Samarth Life Sciences Pvt Ltd
Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Expires on or after
March, 2026
About Endace 160 Tablet
Endace 160 Tablet is a medication used to treat hormone-dependent breast cancer and endometrial cancer. These types of cancer affect the breast cells and the lining of the uterus, leading to symptoms like lumps in the breast, nipple changes, pelvic pain, and abnormal bleeding. Endace 160 Tablet contains Megestrol, which is a Progestogen that works similarly to the female hormone progesterone. It helps slow down cancer progression by interfering with hormone production or action involved in cancer growth.
It is essential to take Endace 160 Tablet as prescribed by your doctor. The dosage and duration of treatment will be determined by your doctor based on your condition. You can take the tablet with or without food, but it is advisable to take it at the same time each day. It is crucial to follow your doctor's instructions and continue taking the medication for the prescribed duration.
Like any medication, Endace 160 Tablet may cause side effects. Common side effects include weight gain, increased appetite, shortness of breath, hot flushes, high blood pressure, and constipation. These side effects are usually temporary and may diminish as your body adjusts to the treatment. If you experience any bothersome side effects, inform your doctor. They may be able to provide solutions to reduce or prevent these side effects.
Before starting Endace 160 Tablet, inform your doctor about any other medications you are taking, as some medications may interact with Endace 160 Tablet. Pregnant and breastfeeding women should not take this medication. Your doctor may recommend regular blood tests to monitor hormone levels and blood sugar while you are on this treatment. It is crucial to follow your doctor's advice and inform them about any health conditions you have, such as diabetes, liver problems, or blood clotting disorders, before starting this medication.
Benefits
Endace 160 Tablet offers significant benefits in the treatment of breast cancer and endometrial cancer. In cases of breast cancer, this medication helps to alleviate distressing symptoms such as breast lumps, bloody discharge from nipples, and changes in breast texture. By modifying the production of vital hormones responsible for the growth and spread of breast cancer, Endace 160 Tablet effectively hinders the progression of the disease. It may also influence other hormones or directly impact the cancer cells to inhibit further growth.
For endometrial cancer, Endace 160 Tablet contains a synthetic hormone that mimics the actions of progesterone. This synthetic hormone effectively addresses symptoms such as abnormal vaginal bleeding, lower back pain, and pain during intercourse associated with endometrial cancer. By disrupting the production and function of hormones crucial for the development and spread of endometrial cancer, this medication plays a crucial role in halting the advancement of the disease. It may also have interactions with other hormones or directly target the cancer cells to impede their growth.
Moreover, the active ingredient 'Megestrol' in Endace 160 Tablet is instrumental in interfering with the production of hormones that contribute to cancer development. This leads to a reduction in cancer symptoms, thereby improving the overall quality of life for patients undergoing treatment. Additionally, Endace 160 Tablet shows promise in managing loss of appetite in individuals with HIV/AIDS. Overall, the benefits of this drug extend beyond cancer treatment, showcasing its versatility in addressing various medical conditions effectively.
How to use the Endace 160 Tablet
To use Endace 160 Tablet, follow your doctor's instructions for the correct dose and duration. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. You can take this tablet with or without food, but it is recommended to take it at the same time each day. If you are using the oral suspension, shake the bottle well before each use. Measure the prescribed liquid dose using a marked measuring spoon, oral syringe, or medicine cup - do not use a household spoon. Follow the liquid dose with water. Your physician will determine the appropriate dosage and treatment duration based on factors like your age, weight, and medical condition. Remember to take Endace 160 Tablet exactly as directed for optimal effectiveness.
Uses of Endace 160 Tablet
Endace 160 Tablet is commonly used in the treatment of hormone-dependent cancers such as breast cancer and endometrial cancer. These types of cancers are influenced by certain hormones in the body. Additionally, this medication may also be prescribed to help manage reduced appetite and weight loss in patients who are in advanced stages of cancer or living with HIV. By targeting the hormone-dependent nature of these cancers, Endace 160 Tablet can help in slowing down the progression of the disease and improving the quality of life for patients going through difficult times.
What conditions Endace 160 Tablet treats?
Endace 160 Tablet is used for treating breast cancer, a type of cancer that starts in breast cells. Symptoms of breast cancer may include a lump in the breast, breast pain, redness, swelling, nipple discharge, changes in breast shape or size, and skin changes. Risk factors for breast cancer include age, family history, and obesity. This medication can also help with endometrial cancer, which affects the lining of the uterus. Endometrial cancer symptoms may include abnormal bleeding, pelvic pain, and pain during sex. Risk factors for endometrial cancer include age, obesity, and certain medical conditions. Early diagnosis and treatment are important for better outcomes.
Should you consult a doctor?
Seek a doctor before taking Endace 160 Tablet if you have diabetes or a history of thrombophlebitis (blood clot due to inflammation). Additionally, if you are intolerant to certain sugars like lactose, it is essential to inform your doctor.
Side effects of Endace 160 Tablet
When taking Endace 160 Tablet, some common side effects may occur but usually don't need medical attention. These effects can include an increase in appetite, weight gain, hot flashes, high blood pressure, and constipation. You might notice changes like feeling your face and neck getting hot, or your face appearing rounder. In some cases, your blood sugar levels might increase. Other symptoms could include shortness of breath, tiredness, weakness, and gastrointestinal issues like nausea, vomiting, and constipation. There may also be swelling in a vein due to a blood clot.
More severe side effects could include changes in mood, numbness in fingers or thumb, hair loss, impotence, frequent urination, and altered vaginal bleeding patterns. You might also experience symptoms like pain, rash, red itchy welts, or the buildup of fluid leading to swelling, particularly in the ankles. If you encounter signs of a blood clot such as loss of coordination, slurred speech, or pain and numbness in your limbs, stop taking the medication and seek immediate medical attention. Additionally, if you notice any signs of an allergic reaction, such as facial swelling, skin rash, or difficulty breathing, contact your doctor right away.
Safety advice

liver
When it comes to using Endace 160 Tablet, caution is advised for patients with severe liver disease. It is important to be aware that in such cases, dose adjustment of the medication may be necessary. Therefore, it is highly recommended to consult your doctor before starting or making any changes to your treatment plan involving Endace 160 Tablet.

kidney
Endace 160 Tablet requires caution in severe kidney disease. Adjustments to the dose may be necessary, consult your doctor.

alcohol
Consult your doctor when consuming alcohol with Endace 160 Tablet.

driving
Endace 160 Tablet typically does not impact driving abilities.

pregnancy
Endace 160 Tablet is not safe to use during pregnancy. Studies have shown harmful effects to the developing baby in pregnant women and animals. Seek your doctor's advice.

breastfeeding
Endace 160 Tablet is not recommended for breastfeeding as it may be unsafe. Limited data shows the drug can pass into breastmilk and potentially harm the baby.
Age above 75(Geriatrics)
Endace 160 Tablet should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking Endace 160 Tablet.
Age below 6 months(Pediatrics)
Endace 160 Tablet is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor for advice.
Consumption warning before consuming Endace 160 Tablet
Before consuming Endace 160 Tablet, it’s crucial to be aware of certain risks and precautions. This medication can heighten the risk of blood clots, especially for individuals with a history of thrombophlebitis. If you experience symptoms such as impaired coordination, difficulty speaking, pain in the groin, arm, or leg (particularly in the calf), shortness of breath, weakness, headache, or dizziness, promptly notify your doctor as these could indicate a potential blood clot. Endace 160 Tablet is not advisable during pregnancy, so reliable contraception is essential while using this medicine, and a pregnancy test may be necessary before starting treatment. Additionally, this medication contains lactose, so it’s important to disclose any sugar intolerance to your healthcare provider.
Disease interactions
When taking Endace 160 Tablet, it is important to be cautious if you have severe liver problems, a history of thrombophlebitis (blood clots), stroke, adrenal gland disorder, or diabetes. Patients with these conditions should use this medication under close monitoring and supervision to avoid potential interactions or complications. It is recommended to consult with a healthcare provider before starting Endace 160 Tablet if you have any of these health issues to ensure safe and effective use of the medication.
What happens if you take overdose of Endace 160 Tablet?
In case of taking an excessive amount of Endace 160 Tablet, it is important to seek help from a doctor or go to the nearest hospital right away to deal with overdose symptoms.
Related lab tests
For patients taking Endace 160 Tablet, related lab tests may include blood tests to monitor specific markers related to Breast Cancer, such as CA 15.3, ER (Estrogen Receptor), and PR (Progesterone Receptor) levels. These tests help in assessing the progression of the cancer and determining the appropriate treatment plan. In addition to blood tests, imaging tests like Computerized Tomography (CT) scan and Positron Emission Tomography (PET) scan may also be recommended to further evaluate the extent of the disease and response to treatment. Regular monitoring through these lab tests is crucial in managing Breast Cancer effectively.
Related Lab Tests:
1. CA 15.3 blood test
2. ER (Estrogen Receptor) and PR (Progesterone Receptor) blood tests
3. Computerized Tomography (CT) scan
4. Positron Emission Tomography (PET) scan
Additional Information
Habit Forming | No |
Chemical Class | Progesterone Congeners |
Therapeutic Class | - |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹1313.47
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 18-Nov-2024