Duzela 40 Capsule DR
By Duzela
Rx
10 Capsule DR in a Strip

Composition
Duloxetine(40mg)

Manufacturer - Sun Pharmaceutical Industries Ltd
Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after
May, 2026
About Duzela 40 Capsule DR
Duzela 40 Capsule DR is a medication that falls under the category of Antidepressants. It is mainly prescribed for individuals dealing with depression and anxiety disorders. Additionally, it is also used to address neuropathic pain conditions such as fibromyalgia linked with diabetic peripheral neuropathy and to manage stress urinary incontinence in women.
Depression is characterized by persistent feelings of sadness or disinterest that significantly affect daily life, while anxiety is a state of unease ranging from mild to severe levels of worry or fear. Fibromyalgia, on the other hand, is a chronic condition causing widespread pain throughout the body, and urinary incontinence refers to the inadvertent leakage of urine, impacting many individuals globally.
Duzela 40 Capsule DR contains Duloxetine, a substance that works by enhancing the levels of serotonin and noradrenaline in the brain. By doing so, this medication helps to balance negative emotions, improve mood, enhance sleep quality, and ultimately enhance the overall quality of life for the individual. This mechanism of action makes Duzela 40 Capsule DR a beneficial option for addressing depressive disorders, anxiety conditions, neuropathic pain, fibromyalgia, and other related health issues.
Common side effects associated with Duzela 40 Capsule DR include nausea, dry mouth, headaches, constipation, and drowsiness. Most of these side effects are temporary and tend to resolve over time without requiring medical intervention. However, if the side effects persist or become bothersome, consulting a healthcare provider is recommended.
It is crucial for individuals using Duzela 40 Capsule DR to adhere to the prescribed dosage regimen and not discontinue or alter the dosage without consulting a doctor. Abruptly stopping the medication can lead to unpleasant symptoms such as vomiting, agitation, confusion, among others. Before initiating treatment with Duzela 40 Capsule DR, informing the healthcare provider about any existing allergies, kidney, liver, or heart conditions is essential to ensure safe usage of the medication.
Individuals who are pregnant, breastfeeding, or under the age of 18 should use Duzela 40 Capsule DR cautiously, as specific safety considerations apply in these cases. During the course of treatment, if there are any thoughts of self-harm or worsening symptoms, seeking immediate medical assistance is recommended. By following the prescribed guidelines and staying in close communication with healthcare providers, individuals can optimize the benefits of Duzela 40 Capsule DR in managing their health conditions effectively.
Benefits
Duzela 40 Capsule DR offers various benefits in treating different conditions. Firstly, when used for treating depression, this medication enhances the levels of certain chemicals in the brain, leading to an improvement in mood and behavior. It helps in reducing anxiety, tension, and sleep problems while also boosting energy levels, providing a sense of well-being. It is essential to take this medicine regularly as prescribed to experience its full effectiveness and avoid worsening of the condition upon sudden cessation of use.
Secondly, in the treatment of anxiety disorders, Duzela 40 Capsule DR works by inhibiting the release of anxiety-inducing chemicals in the brain. This helps in alleviating symptoms of excessive worry, restlessness, fatigue, and difficulties in concentration, enabling individuals to carry out daily activities more smoothly. Continuation of this medication, even if feeling better, is crucial to prevent potential serious issues upon abrupt discontinuation.
Additionally, for diabetic nerve pain, this medication plays a role in reducing nerve damage caused by high blood sugar levels. By interacting with neurotransmitters in the brain, it helps alleviate pain sensations and subsequently enhances the quality of life for individuals experiencing diabetic nerve pain.
Moreover, Duzela 40 Capsule DR is also beneficial in treating fibromyalgia-related pain by reducing pain intensity and associated symptoms like mood changes, sleep disturbances, and fatigue. The drug disrupts pain signals within the brain, contributing to an overall improvement in the quality of life when taken as advised by the healthcare provider.
Furthermore, in cases of neuropathic pain resulting from nerve damage, Duzela 40 Capsule DR is effective in interfering with pain signals, aiding in the management of chronic pain conditions caused by diabetes, shingles, or spinal cord injuries. Consistent use of the medication is essential for enhancing physical and social functioning and overall quality of life.
Lastly, Duzela 40 Capsule DR can also assist in treating stress urinary incontinence by enhancing the activity of nerves in the brain responsible for controlling bladder muscles. This contributes to improved bladder control, particularly benefiting women experiencing stress urinary incontinence.
In conclusion, Duzela 40 Capsule DR offers valuable benefits in addressing depression, anxiety disorders, diabetic nerve pain, fibromyalgia-related pain, neuropathic pain, and stress urinary incontinence. Its mechanism of action in restoring the balance of certain brain chemicals yields positive outcomes in improving mood, reducing pain, enhancing quality of life, and promoting overall well-being for individuals in need of these treatments.
How to use the Duzela 40 Capsule DR
To use Duzela 40 Capsule DR effectively, follow your doctor's prescribed dose and duration. Swallow the capsule whole with a glass of water; do not chew, crush, or break it. While you can take Duzela 40 Capsule DR with or without food, it is recommended to take it at the same time each day. Consistency in timing can help you remember your dose.
Ensure you follow your physician's guidance on taking Duzela 40 Capsule DR. Your doctor will determine the appropriate dosage and duration based on factors like your age, weight, and the severity of your condition. It's essential not to discontinue the medication unless advised by your doctor, even if you start feeling better. By adhering to your doctor's instructions and maintaining a regular schedule, you can maximize the benefits of Duzela 40 Capsule DR in managing your health effectively.
Uses of Duzela 40 Capsule DR
"Duzela 40 Capsule DR is used for treating various conditions including depression, anxiety disorder, diabetic nerve pain, fibromyalgia, neuropathic pain, and stress urinary incontinence. It is effective in managing major depressive disorders, diabetic neuropathic pain, generalized anxiety disorder, and stress urinary incontinence in women. This medication can help alleviate symptoms such as chronic muscle or joint pain, providing relief and improving overall quality of life for individuals dealing with these conditions."
What conditions Duzela 40 Capsule DR treats?
Duzela 40 Capsule DR is used in the treatment of major depressive disorder, generalized anxiety disorder (GAD), diabetic neuropathy, and fibromyalgia. Major depressive disorder affects mood, behavior, and physical activities, leading to symptoms like reduced interest in daily activities and changes in appetite. GAD causes excessive worry and symptoms such as fatigue and trouble sleeping. Diabetic neuropathy damages nerves due to high blood sugar, with common symptoms like bloating and vomiting. Fibromyalgia causes musculoskeletal pain and other issues like fatigue and memory problems, more common in women.
Should you consult a doctor?
Seek a doctor if you experience seizures, manic episodes, or eye problems like glaucoma while taking Duzela 40mg Capsule DR. Additionally, consult a healthcare provider if you have a history of bleeding disorders or are at risk of low sodium levels, especially if you are taking water tablets or are elderly. It is crucial to inform your doctor about these conditions before starting the medication to ensure your safety and proper management of any potential side effects.
Side effects of Duzela 40 Capsule DR
Side Effects:
When taking Duzela 40 Capsule DR, some common side effects you may experience include nausea, headache, dry mouth, sleepiness, and dizziness. These side effects usually fade as your body gets used to the medication, but if they persist or cause concern, it's important to consult your doctor. Other potential side effects include difficulty sleeping, blurry vision, constipation, diarrhea, and feelings of sickness or vomiting. Some individuals may also experience reduced appetite, weight loss, diminished interest in sex, and erection issues.
In rare cases, more severe side effects may occur, such as throat inflammation resulting in a hoarse voice, suicidal thoughts, disorientation, trouble sleeping, and abnormal teeth grinding. Other serious side effects may include involuntary muscle twitches, nervousness, taste changes, coordination difficulties, restless leg syndrome, vision problems, ear pain, and irregular heartbeat. Additional uncommon side effects can manifest as lightheadedness upon standing, throat tightness, nose bleeds, gastrointestinal issues like vomiting blood or black stools, liver inflammation, night sweats, and increased bruising tendency.
It is crucial to seek immediate medical attention if you experience certain severe side effects while using Duzela 40 Capsule DR, such as uncontrollable movements, chest pain, dehydration, mania, hallucinations, serotonin syndrome, seizures, glaucoma symptoms, difficulty breathing, liver failure signs, or severe skin reactions like Stevens-Johnson syndrome. Additionally, if you encounter symptoms like restlessness, self-harm thoughts, or any other concerning effects, stop taking the medication and contact your healthcare provider promptly.
Safety advice

liver
Duzela 40 Capsule DR is not recommended for use in patients with liver disease. It is likely unsafe for individuals with liver issues, and it is advisable to avoid using this medication if you have such conditions. It is important to consult your doctor for guidance before considering the use of Duzela 40 Capsule DR.

kidney
Duzela 40 Capsule DR should be used carefully in patients with severe kidney disease. It may require dose adjustment. Consult your doctor beforehand. No dose adjustment is needed for mild to moderate kidney disease.

alcohol
It is unsafe to drink alcohol while taking Duzela 40 Capsule DR.

driving
Duzela 40 Capsule DR may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if experiencing these effects.

pregnancy
Duzela 40 Capsule DR is considered unsafe during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing. It is important to consult with your doctor regarding its use during pregnancy.

breastfeeding
Duzela 40 Capsule DR is likely unsafe for breastfeeding. Limited data shows the drug could pass into breastmilk and harm the baby.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Duzela 40 Capsule DR
Before consuming Duzela 40 Capsule DR, it is crucial to be aware of certain precautions to ensure your safety. Firstly, avoid using this medication within 5 days before or 14 days after taking MAO inhibitors like rasagiline, selegiline, or linezolid to prevent serious drug interactions. Do not abruptly discontinue Duzela 40 Capsule DR without consulting a medical professional as it can lead to severe withdrawal symptoms. During your consultation, inform your doctor about any existing heart issues, high blood pressure, liver or kidney problems, slow digestion, or a history of seizures. If you are pregnant or breastfeeding, it is essential to discuss this with your healthcare provider. Additionally, refrain from engaging in hazardous activities as Duzela 40 Capsule DR may induce drowsiness, necessitating proper rest.
What if you forgot to take Duzela 40 Capsule DR?
If you forget to take a dose of Duzela 40 Capsule DR, try to take it as soon as you remember. But if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. Consistency in taking your medication is key for its effectiveness.
What happens if you take overdose of Duzela 40 Capsule DR?
If you or someone has taken too much of Duzela 40mg Capsule, it is important to seek immediate medical attention. Overdosing on Duzela 40mg Capsule can lead to various symptoms including sleepiness, serotonin syndrome (which may cause feelings of extreme happiness, drowsiness, clumsiness, restlessness, feeling intoxicated, fever, sweating, and rigid muscles), seizures, vomiting, and a fast heart rate. If an overdose is suspected, contact your doctor or go to the nearest hospital for prompt evaluation and treatment.
Related lab tests
For patients taking Duzela 40 Capsule DR, it is important to monitor their Glycosylated Hemoglobin levels regularly. This test, also known as HbA1c, provides valuable information about a person's average blood sugar levels over the past 2-3 months. It is especially important for individuals with diabetes, as it helps in assessing their long-term blood sugar control. High levels of Glycosylated Hemoglobin indicate poorly controlled diabetes, while lower levels suggest better management of the condition. By monitoring this lab test, healthcare providers can make informed decisions regarding the treatment plan and lifestyle modifications for patients taking Duzela 40 Capsule DR.
Related Lab Tests:
- Glycosylated Hemoglobin (HbA1c)
Additional Information
Habit Forming | No |
Chemical Class | Naphthalene Derivative |
Therapeutic Class | NEURO CNS |
Action Class | Serotonin-norepinephrine reuptake inhibitors (SNRIs) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹227
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 11-Feb-2025