Divalrate 125mg Tablet ER
By Divalrate
Rx
10 Tablet ER in a Strip

Composition
Divalproex(125mg)

Manufacturer - Ipca Laboratories Ltd
142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Expires on or after
October, 2025
About Divalrate 125mg Tablet ER
Divalrate 125mg Tablet ER is a medication primarily used for epilepsy treatment to help prevent and control seizures, commonly known as fits. It is also prescribed for managing migraines and occasionally for bipolar disorder. This medicine can be taken alone or in combination with other medications as determined by your doctor. The dosage and frequency of Divalrate 125mg Tablet ER should be decided by your healthcare provider to effectively manage your symptoms. It can be taken with or without food, but consistency in taking it at the same time daily is beneficial for optimal results.
The effectiveness of Divalrate 125mg Tablet ER may take a few weeks to manifest, hence it is crucial to take it regularly and for the prescribed duration, even if feeling well. Abruptly stopping the medication can lead to worsening of the condition and potential triggering of seizures. Commonly reported side effects of this medication include headache, blurred vision, nausea, vomiting, dizziness, tiredness, unsteadiness, bruising, decreased body temperature, among others. While most side effects are mild, persistent issues should be discussed with your doctor. If you notice a skin rash or redness, prompt medical attention is advised.
Long-term use of Divalrate 125mg Tablet ER may result in the development of osteoporosis and an increased risk of bone fractures. Rarely, this medication may lead to suicidal thoughts and behaviors; if experiencing mood changes or depression, informing your doctor is important. Prior to starting treatment with Divalrate 125mg Tablet ER, disclose any history of heart problems, kidney or liver issues, urinary difficulties, depression, or suicidal thoughts to your healthcare provider. Additionally, it is essential to inform your doctor about all medications you are taking to avoid any potential interactions.
Pregnant individuals should consult their doctor before starting or stopping Divalrate 125mg Tablet ER, as it may not be suitable during pregnancy. Alcohol consumption should be avoided while taking this medication, as it can exacerbate certain side effects and increase the risk of seizures. Regular blood tests may be necessary to ensure the appropriate dosage throughout the treatment period. It is vital to follow your doctor's guidance and communicate any concerns or adverse effects occurring during the use of Divalrate 125mg Tablet ER.
Benefits
Divalrate 125mg Tablet ER, belonging to the group of medicines called anticonvulsants or anti-epileptics, offers multiple benefits for various conditions. Firstly, in the treatment of epilepsy/seizures, this medication acts as an anticonvulsant to reduce nerve impulses that trigger seizures. By controlling seizure frequency, Divalrate 125mg Tablet ER helps individuals lead a more confident and active daily life by minimizing symptoms like confusion, uncontrollable movements, and fear.
Moreover, for individuals with bipolar disorder, Divalrate 125mg Tablet ER plays a crucial role in restoring the balance of nerve activity in the brain. This helps in preventing extreme mood swings and reducing agitation, leading to fewer episodes of low mood over time. While it may take a few weeks for the medication to show its effects, it is essential to continue the prescribed regimen for at least six months to achieve optimal results. Regular intake of Divalrate 125mg Tablet ER, under medical supervision, is key to managing bipolar disorder effectively.
Furthermore, Divalrate 125mg Tablet ER is also utilized in the prevention of migraines. Although the exact mechanism is not entirely understood, this medication is thought to modify nerve cell activity in the brain, potentially reducing the occurrence of migraines. By preventing and lessening the frequency of headaches, Divalrate 125mg Tablet ER enables individuals to carry out daily activities with greater ease, leading to an improved quality of life.
In conclusion, Divalrate 125mg Tablet ER offers significant benefits in the management of epilepsy/seizures, bipolar disorder, and migraine prevention. Its ability to regulate nerve activity in the brain, control seizures, stabilize mood swings, and reduce migraine occurrence makes it a valuable medication for those struggling with these conditions. It is essential to adhere to the prescribed dosage and regimen to maximize the effectiveness of Divalrate 125mg Tablet ER and alleviate symptoms associated with these medical conditions.
How to use the Divalrate 125mg Tablet ER
To use Divalrate 125mg Tablet ER, it is important to follow your doctor's instructions regarding the dose and duration of the medication. When taking the tablet, swallow it whole with a glass of water; do not chew, crush, or break it. You can take Divalrate 125mg Tablet ER with or without food, but it is recommended to take it at the same time each day for better results.
If you are prescribed Dicorate ER 500mg Tablet, also swallow it whole with water without crushing or chewing it. Your physician will determine the appropriate dosage and duration based on factors such as your age, weight, and medical condition. It is essential to adhere to your doctor's recommendations for the most effective and safe usage of the medication.
For other forms of Dicorate, such as syrup, suspension, drops, or sprinkle capsules, follow the specific instructions provided with the packaging. For syrup, suspension, or drops, use the measuring cup, dosing syringe, or dropper provided in the pack to take the prescribed dose orally. Shake the pack well before each use to ensure proper mixing. If you are using sprinkle capsules, swallow them whole with water or sprinkle the contents on food before consumption.
Remember, it is crucial to take Dicorate ER tablets exactly as prescribed to achieve the desired therapeutic effects and avoid any potential side effects. If you have any questions or concerns about how to use the medication, do not hesitate to consult your doctor or pharmacist for guidance.
Uses of Divalrate 125mg Tablet ER
Divalrate 125mg Tablet ER is used for treating epilepsy, bipolar disorder, and preventing migraine attacks. It effectively manages mania and bipolar disorder symptoms. This medication is also beneficial in controlling complex partial seizures, both with and without other seizure types. Additionally, Divalrate 125mg Tablet ER is used to prevent migraine headaches.
What conditions Divalrate 125mg Tablet ER treats?
Divalrate 125mg Tablet ER is used in the treatment of epilepsy. Epilepsy is a condition where there is abnormal nerve cell activity in the brain, causing sudden rushes of electricity leading to recurrent seizures. Seizures can manifest as uncontrollable muscle twitches, confusion, or unconsciousness. The electrical rhythms in the brain become imbalanced during seizures, affecting consciousness, movements, and sensations. Epilepsy can be caused by factors such as high fever, trauma, genetic disorders, brain injury, or stroke.
Should you consult a doctor?
It is important to seek medical attention when taking Divalrate 125mg Tablet ER if you experience any concerning symptoms or conditions. Seek a doctor if you have a history of POLG and its associated disorder, especially in children under 2 years old, or urea cycle disorders. Before taking the tablet, inform your doctor if you have systemic lupus erythematosus, porphyria, bleeding or other blood disorders, pancreatitis, hyperammonemia, hyperammonemic encephalopathy, or DRESS syndrome. These conditions may interact with Divalrate 125mg Tablet ER and require medical supervision for safe usage.
Side effects of Divalrate 125mg Tablet ER
Divalrate 125mg Tablet ER may cause various side effects, although most of them are temporary and tend to improve as your body gets used to the medication. Common side effects include decreased body temperature, dizziness, sleepiness, tremors, tingling sensations, anemia, decreased sodium levels in the blood, liver injury, gastrointestinal disturbances, hypersensitivity, deafness, urinary incontinence, weight gain, and pain during periods. Additionally, you may experience abdominal pain, back pain, constipation, diarrhea, nausea, increased appetite, vomiting, vision problems, changes in weight, and issues with walking or coordination. More severe side effects that require immediate medical attention include bleeding problems, high ammonia levels in the blood, low body temperature, allergic reactions, drowsiness in the elderly, persistent nausea or vomiting, inflammation of the pancreas, and thoughts of self-harm or suicide. It is crucial to consult your doctor if you experience any concerning side effects or if your symptoms persist.
Safety advice

liver
Divalrate 125mg Tablet ER may be unsafe for individuals with liver disease, and it is advisable to avoid using it. It is crucial to consult your doctor before taking this medication.

kidney
Divalrate 125mg Tablet ER is safe for use in patients with kidney disease. It does not require any dose adjustment.

alcohol
Divalrate 125mg Tablet ER can lead to increased drowsiness when taken with alcohol.

driving
Divalrate 125mg Tablet ER may have side effects that can impact driving ability.

pregnancy
Divalrate 125mg Tablet ER should not be used during pregnancy due to the risk to the developing baby. In certain life-threatening situations, a doctor may prescribe it if benefits outweigh risks. Consult your doctor before use.

breastfeeding
Divalrate 125mg Tablet ER is safe to use during breastfeeding. Studies show the drug does not pass into breastmilk in significant amount and is not harmful to the baby.
Age above 75(Geriatrics)
Divalrate 125mg Tablet ER should be used with caution in elderly patients (aged above 65 years) with kidney impairment. Consult your physician before taking Divalrate 125mg Tablet ER.
Age below 6 months(Pediatrics)
Divalrate 125mg Tablet ER is not recommended for use in children (under 10 years of age) as it has not been shown to be safe and effective in this age group. It should be used with caution in children (10 years and older). Consult your physician before taking Divalrate 125mg Tablet ER TABLET.
Consumption warning before consuming Divalrate 125mg Tablet ER
Before consuming Divalrate 125mg Tablet ER 10's, it is crucial to consider the following warnings. Do not take this medication if you have allergies to any of its components, liver issues, or urea cycle disorders. Prior to starting Divalrate 125mg Tablet ER 10's, inform your healthcare provider if you have pancreatitis, blood complications, or multi-organ hypersensitivity. Seek immediate medical attention if you notice any signs of suicidal thoughts while using this medication. Possible side effects include thrombocytopenia, hyperammonemia, hypothermia, and liver problems. It is essential not to discontinue Divalrate 125mg Tablet ER 10's without consulting your doctor to prevent seizure exacerbation. Avoid using this medication during pregnancy to avoid birth defects, and utilize effective contraception if you are of childbearing age. If you are breastfeeding, consult your doctor before taking Divalrate 125mg Tablet ER 10's. Exercise caution when driving or operating machinery due to potential dizziness and impaired cognitive and motor functions. Refrain from alcohol consumption alongside this medication to prevent increased dizziness. Special care is necessary when administering Divalrate 125mg Tablet ER 10's to children under 2 years due to a heightened risk of liver toxicity during the initial six months of treatment.
Disease interactions
Divalrate 125mg Tablet ER 10's can have interactions with various disease conditions. It is important to be cautious if you have depression, liver disease, urea cycle disorders, suicidal tendencies, HIV disease, or thrombocytopenia (low platelet levels) while taking this medication. These conditions may affect how Divalrate 125mg Tablet ER 10's work in your body or may increase the risk of side effects. It is best to consult your healthcare provider for guidance on how to manage these interactions, and to ensure the safe and effective use of the medication.
What if you forgot to take Divalrate 125mg Tablet ER?
If you forget to take a dose of Divalrate 125mg Tablet ER, try to take it as soon as you remember. However, if it is almost time for your next scheduled dose, then it's better to skip the missed dose and continue with your usual dosing routine. It's important not to double up on doses to make up for the missed one. Just carry on with your next dose as prescribed. This helps maintain the proper level of medication in your system and reduces the risk of any potential side effects.
What happens if you take overdose of Divalrate 125mg Tablet ER?
An overdose of Divalrate 125mg Tablet ER can occur if you or someone else takes too much of the medication. In case of an overdose, it is crucial to seek immediate medical help by consulting your physician or going to the nearest hospital. Symptoms of an overdose may include drowsiness, heart block, and deep coma. If you experience any of these symptoms after taking Divalrate 125mg Tablet ER, it is important to seek medical attention promptly to prevent any potential complications.
Related lab tests
In order to monitor the effects and progress of treatment with Divalrate 125mg Tablet ER, certain lab tests may be recommended by your healthcare provider. These tests can provide valuable information to assess your condition and response to the medication. Two important lab tests commonly used in relation to Divalrate 125mg Tablet ER are Electroencephalogram (EEG) and MRI.
1. Electroencephalogram (EEG): An EEG is a test that measures the electrical activity in the brain. It is commonly used in patients with epilepsy or other neurological conditions to assess brain function and detect abnormalities. EEG can help in determining the response of the brain to Divalrate 125mg Tablet ER and monitor any changes in brain activity over time.
2. MRI (Magnetic Resonance Imaging): An MRI is a non-invasive imaging test that uses strong magnetic fields and radio waves to create detailed images of the brain. It is often used to diagnose and monitor various neurological conditions, such as brain tumors, strokes, or multiple sclerosis. MRI can provide valuable insights into the effects of Divalrate 125mg Tablet ER on the brain structure and any changes that may occur during treatment.
These lab tests are important tools in evaluating the effectiveness of Divalrate 125mg Tablet ER and ensuring the best possible management of your condition. Your healthcare provider may recommend these tests at specific intervals to closely monitor your progress and make any necessary adjustments to your treatment plan.
Additional Information
Habit Forming | No |
Chemical Class | Aliphatic Carboxylic acid Derivatives |
Therapeutic Class | NEURO CNS |
Action Class | Sodium channel modulators (AED) |
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Content verified by

Dr. Mansi Chaudhari
MBBS - General Medicine
Last update on 01-Oct-2024