Distinon Tablet
By Distinon
Rx
10 Tablet in a Strip

Composition
Pyridostigmine(60mg)

Manufacturer - Samarth Life Sciences Pvt Ltd
Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Expires on or after
July, 2026
About Distinon Tablet
Distinon Tablet is a medication used in treating various conditions such as myasthenia gravis, paralytic ileus, and postoperative urinary retention. Myasthenia gravis is a chronic neuromuscular disease that causes muscle weakness due to excessive activity of a protein called cholinesterase. Distinon contains Pyridostigmine, which belongs to a group of medicines known as cholinesterase inhibitors. This medication works by inhibiting the excessive cholinesterase activity needed to break down a neurotransmitter called acetylcholine, crucial for nerve-to-muscle communication.
It is recommended to take Distinon Tablet on an empty stomach, about 30-60 minutes before meals. Swallow the tablet whole without crushing or chewing. Consistency in timing and dosage is essential, following your doctor's instructions throughout the treatment duration. Missing a dose should be rectified by taking it as soon as remembered, but avoiding double doses. Abruptly stopping the medication is not advised without consulting your doctor to avoid potential risks.
Common side effects associated with Distinon Tablet include nausea, excessive salivation, diarrhea, blurred vision, shortness of breath, and abdominal pain. Other possible side effects may include sweating, headache, runny nose, and heartburn, as well as dizziness and drowsiness. Engaging in activities requiring focus, such as driving or operating machinery, should be approached cautiously due to potential effects on alertness and coordination.
Before starting Distinon Tablet, inform your healthcare provider if you have kidney issues, Parkinson's disease, asthma, or stomach disorders. Monitoring blood pressure is advisable due to potential decreases after taking the medicine. Hydration is important to counteract possible diarrhea caused by Distinon Tablet. It is crucial to discuss pregnancy, planning for conception, or breastfeeding with your doctor before starting this medication to ensure safety and potential adjustments based on individual health factors.
Benefits
Distinon Tablet offers significant benefits in treating various conditions effectively. For individuals suffering from Myasthenia gravis, a neuromuscular disorder causing muscle weakness in areas like the eyes, face, and swallowing, this medication plays a crucial role. By enhancing the coordination between muscles and nerves, Distinon Tablet alleviates symptoms such as double vision, drooping eyelids, and difficulty in speaking and walking. Ultimately, it boosts muscle strength, leading to an improved quality of life for the individual.
Moreover, Distinon Tablet proves beneficial in addressing Paralytic ileus, a condition characterized by intestinal obstruction due to nerve and muscle dysfunction in the intestine. By stimulating contractions in the intestinal muscles, this medication enhances digestive movement, thus resolving the obstruction and promoting better food passage. It is essential to follow the doctor’s guidance closely to ensure optimal results.
Furthermore, individuals experiencing post-operative urinary retention, a common issue following surgery resulting from disrupted coordination between bladder muscles and nerves, can benefit from Distinon Tablet. This medication effectively improves bladder function, aiding in the treatment of post-operative urinary retention. Adhering to the prescribed dosage and guidelines from your healthcare provider is key to addressing this concern efficiently.
In conclusion, Distinon Tablet's ability to enhance coordination between nerves and muscles, leading to symptom relief and improved function, makes it a valuable treatment option for Myasthenia gravis, Paralytic ileus, and post-operative urinary retention. By following medical advice diligently, individuals can experience the full benefits of this medication and pave the way for a healthier and more comfortable life.
How to use the Distinon Tablet
To use Distinon Tablet, follow the instructions given by your doctor on dosage and duration. Swallow the tablet whole and do not chew, crush, or break it. It is important to take this medicine on an empty stomach for best results. Remember to always consult your doctor before starting or changing any medication regimen.
Uses of Distinon Tablet
Distinon Tablet is primarily used for the treatment of Myasthenia gravis, a condition that causes muscle weakness and fatigue. It is also effective in treating Paralytic ileus, a condition where there is a lack of movement in the intestines leading to digestive issues. Additionally, this tablet can help with Post-operative urinary retention, a condition where a person has difficulty emptying their bladder after surgery. Distinon Tablet is a versatile medication that can be beneficial in various medical conditions related to muscle weakness and discomfort.
What conditions Distinon Tablet treats?
Distinon Tablet is used to treat myasthenia gravis, a condition causing muscle weakness and fatigue. It also helps with paralytic ileus, where intestinal muscles are paralyzed, and postoperative urinary retention. By strengthening muscles, promoting bowel function, and stimulating bladder muscles, this medication aids in improving these conditions. Distinon Tablet should be taken on an empty stomach at the same time each day. Some common side effects may include nausea, blurred vision, and abdominal pain. It is important not to suddenly stop taking this medicine without consulting your doctor. Inform your doctor of any existing medical conditions before starting this treatment.
Should you consult a doctor?
Seek medical attention immediately if you experience severe side effects such as difficulty breathing, chest pain, fainting, or swelling of the face, lips, tongue, or throat. Contact your doctor if you notice persistent and troubling side effects like severe nausea, vomiting, or diarrhea that do not improve. It is essential to seek medical advice if you develop any new symptoms or if existing side effects worsen over time. Additionally, if you have any concerns about the medication or its effects on your health, do not hesitate to consult your healthcare provider for guidance. Remember to inform your doctor about any pre-existing medical conditions or medications you are currently taking to ensure safe and effective use of Distinon Tablet.
Side effects of Distinon Tablet
When taking Distinon Tablet, you may experience some side effects. Most of these side effects are not severe and tend to go away as your body gets used to the medication. However, if these side effects persist or you find them concerning, it is advisable to consult your doctor. Common side effects you may encounter include nausea, excessive salivation, diarrhea, blurred vision, breathlessness, watery eyes, abdominal pain, altered frequency of urination, sweating, headache, dizziness, runny nose, heartburn, gastro-esophageal reflux disease, paresthesia (tingling or pricking sensation), muscle twitching, weakness, muscle cramp, and increased bronchial secretions. Be sure to discuss any persistent or bothersome side effects with your healthcare provider.
Safety advice

liver
Limited information is currently available regarding the use of Distinon Tablet in individuals with liver disease. It is recommended to consult with your doctor for guidance before taking this medication.

kidney
Distinon Tablet requires caution in kidney patients. Consult your doctor for possible dose adjustments.

alcohol
Consult your doctor when consuming alcohol with Distinon Tablet.

driving
Distinon Tablet can lower alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these effects. This medicine may impair eyesight and driving abilities. Refrain from driving or operating machinery if vision is affected.

pregnancy
Distinon Tablet is considered safe during pregnancy based on animal studies showing minimal adverse effects on the baby. Limited human studies are available.

breastfeeding
During breastfeeding, Distinon Tablet is considered safe based on limited data showing no significant risk to the baby.
Consumption warning before consuming Distinon Tablet
Before consuming Distinon Tablet, it is essential to be aware of some precautions. This medication is typically prescribed for conditions like myasthenia gravis, paralytic ileus, and postoperative urinary retention. Ensure to take it on an empty stomach at the same time daily, following your doctor's instructions. If you miss a dose, take it promptly, but do not skip any doses and complete the full course of treatment. Abruptly stopping this medication can be harmful, so always consult your doctor before making any changes.
Possible side effects of Distinon Tablet may include nausea, excessive salivation, diarrhea, blurred vision, and dizziness. Avoid tasks requiring focus, such as driving or operating machinery, if you experience dizziness or sleepiness. Inform your doctor if you have kidney issues, Parkinson's disease, asthma, or stomach disorders before starting this medication. Monitor your blood pressure regularly, as it may decrease. Drinking plenty of fluids can help manage potential diarrhea while taking this medicine. If you are pregnant, planning pregnancy, or breastfeeding, discuss with your doctor before using this medication.
What if you forgot to take Distinon Tablet?
If you forget to take a dose of Distinon Tablet, take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed one and continue with your normal dosing schedule. It's important not to double up on doses to make up for the missed one.
Related lab tests
For patients taking Distinon Tablet, doctors may recommend a lab test to check for Acetyl Choline Receptor Antibody levels. This test helps in diagnosing conditions related to the neuromuscular junction, such as myasthenia gravis. High levels of Acetyl Choline Receptor Antibodies in the blood can indicate the presence of autoantibodies that target the acetylcholine receptors, leading to muscle weakness and fatigue. Monitoring these antibody levels can help in assessing the disease progression and response to treatment. In addition to this test, other related lab tests may include:
1. Complete Blood Count (CBC): To check for any abnormalities in blood cell counts.
2. Electromyography (EMG): To evaluate the electrical activity of muscles.
3. Thyroid Function Tests: To assess thyroid hormone levels, as thyroid disorders can sometimes be associated with myasthenia gravis.
4. Chest X-ray: To check for any thymoma (tumor of the thymus gland) which can be associated with myasthenia gravis.
Consult with your healthcare provider to determine the specific lab tests needed based on your individual health condition and treatment plan.
Additional Information
Habit Forming | No |
Chemical Class | N-Methylpyridinium Compounds |
Therapeutic Class | NEURO CNS |
Action Class | Cholinesterase inhibitors- carbamates |
FAQs
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024