D-NIB Injection
By D-NIB
Rx
1 Powder for Injection in a Vial

Composition
Decitabine(50mg)

Manufacturer - BDR Pharmaceuticals Internationals Pvt
407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020

Expires on or after
August, 2025
About D-NIB Injection
D-NIB Injection is a medication used to treat a type of blood cancer known as acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS). In some cases, it may also be prescribed for other medical conditions, as determined by the doctor. This injection is typically administered in combination with other medicines as part of chemotherapy. It is given directly into a vein under the supervision of a healthcare professional. The dosage and frequency of the injection will be determined by your doctor based on your specific medical condition, and it is crucial to follow their instructions carefully to avoid serious side effects.
It is important to note that the benefits of D-NIB Injection may not be immediately noticeable, and it could take weeks or even months to see or feel any improvements in your condition. It is essential to continue taking the medication as prescribed by your doctor and not discontinue the treatment unless advised to do so. Taking the medication incorrectly or in excess can lead to severe side effects.
Common side effects of D-NIB Injection may include nausea, vomiting, diarrhea, headache, fever, and lung infections. This medication can also lead to a decrease in the number of blood cells, making the body more susceptible to infections. Regular blood tests are necessary to monitor blood cell counts, as well as heart, liver, and blood uric acid levels during treatment.
Before starting D-NIB Injection, it is crucial to inform your doctor if you have any underlying conditions such as heart disease, liver or kidney problems, or if you are taking any medications for infections. This medication can interact with other drugs, so it is important to disclose all medications you are currently using to your doctor. D-NIB Injection is not recommended during pregnancy or while breastfeeding, and the use of effective contraception by both males and females during treatment is advised to prevent pregnancy.
Benefits
D-NIB Injection offers significant benefits in the treatment of Myelodysplastic syndrome, a group of conditions where the bone marrow produces abnormal blood cells. This medicine works by killing or halting the growth of cancer cells in the bone marrow, ultimately leading to increased production of healthy blood cells. By preventing the multiplication of cancer cells, D-NIB Injection plays a crucial role in managing this syndrome effectively. It is essential for patients to have a thorough discussion with their doctor regarding the potential risks and benefits associated with this medication.
Moreover, in the case of blood cancer, also known as leukemia, D-NIB Injection proves to be beneficial in targeting and destroying cancer cells in the blood-forming tissues. By inhibiting the growth and spread of cancer cells, this medication helps enhance the body's capability to combat infections. However, it is important for individuals undergoing this treatment to have open communication with their healthcare provider about the possible side effects and advantages of D-NIB Injection. It is advisable to promptly inform the doctor of any bothersome side effects experienced during the course of treatment.
As with any potent medication, D-NIB Injection is known to be a highly effective yet potentially toxic drug. Patients are advised to abstain from consuming alcohol while on this medication and ensure adequate hydration by drinking plenty of water. Through its ability to target and disrupt cancer cell growth, D-NIB Injection stands as a valuable tool in the treatment and management of Myelodysplastic syndrome and blood cancer, offering hope for patients in combating these challenging conditions.
How to use the D-NIB Injection
When it comes to using D-NIB Injection, it is important to remember that only your doctor or nurse should administer this medicine to you. It is not safe to try to give yourself this injection, so always rely on a healthcare professional for this purpose. Trust your doctor or nurse to handle the injection process correctly and safely. Follow their instructions carefully and make sure to ask any questions you may have about the injection. By having a trained professional administer D-NIB Injection, you can ensure that you are receiving the proper dosage and that the injection is being done correctly to achieve the desired effects.
Uses of D-NIB Injection
D-NIB Injection is utilized in the treatment of myelodysplastic syndrome, a type of blood cancer. It is administered to patients as a therapeutic intervention for this specific medical condition.
What conditions D-NIB Injection treats?
D-NIB Injection is used to treat a blood cancer called acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It may also be used to treat other conditions as directed by the doctor. When used with combination chemotherapy, it is administered as an injection into the vein under supervision. Side effects may include nausea, vomiting, diarrhea, headache, fever, and lung infection. Regular blood tests are required to monitor blood cell counts. Not recommended during pregnancy or breastfeeding. Your doctor will determine the appropriate dosage based on your condition.
Should you consult a doctor?
Seek immediate medical attention if you experience severe side effects such as difficulty breathing, chest pain, swelling in the face or throat, or signs of an allergic reaction like rash, itching, or swelling. Contact your doctor if you have persistent nausea, vomiting, headache, fever, or lung infection. Additionally, seek medical advice if you notice unusual bruising or bleeding, persistent nosebleeds, weakness, or fatigue. It is vital to consult your doctor if you develop symptoms of anemia such as pale skin, dizziness, or shortness of breath, as well as if you have diarrhea that does not improve. Contact your healthcare provider if you experience symptoms indicating a low blood platelet count, such as increased bleeding or bruising. Regular monitoring through blood tests is crucial, so inform your doctor if you notice any significant changes between tests or if you have concerns about your health while taking D-NIB Injection.
Side effects of D-NIB Injection
When using D-NIB Injection, you may experience side effects, although most of these typically do not require medical intervention and tend to diminish as your body becomes accustomed to the medication. However, it is essential to consult your doctor if these side effects persist or cause concern. Possible side effects may include nausea, vomiting, headache, fever, lung infection, decreased white blood cell count (neutrophils), nosebleeds, anemia (low red blood cell count), low blood platelets, diarrhea, and pneumonia. Monitoring how your body responds to the injection is crucial, and any unusual or persistent symptoms should be promptly discussed with your healthcare provider.
Safety advice

liver
Limited information is available regarding the use of D-NIB Injection in patients with liver disease. It is important to consult with your doctor regarding safety advice specific to liver issues before using this medication.

kidney
D-NIB Injection requires caution in patients with kidney disease. Adjusting the dosage may be necessary. Seek advice from your doctor regarding kidney-related issues.

alcohol
It is unclear if alcohol is safe with D-NIB Injection. Consult your doctor before consuming alcohol with this medication.

driving
After using D-NIB Injection, you may feel tired or weak, which can impact your driving ability. Be cautious when driving, as the side effects can affect focus and reaction time.

pregnancy
D-NIB Injection should not be used during pregnancy due to risks to the baby. In rare cases of life-threatening situations, a doctor may prescribe it only if benefits outweigh risks. Always consult your doctor before using.

breastfeeding
Caution should be taken while breastfeeding as D-NIB Injection may be harmful and cause toxicity to the baby. It is advised to consult a doctor before using this medication.
Consumption warning before consuming D-NIB Injection
Before consuming D-NIB Injection, it is important to be aware of certain precautions and warnings. This medication is primarily used for the treatment of conditions such as acute myeloid leukemia and myelodysplastic syndrome. It may also be prescribed for other conditions determined by your doctor. D-NIB Injection is administered through a vein under the supervision of a healthcare professional, who will determine the appropriate dosage and frequency.
It is crucial to strictly follow your doctor's instructions regarding the dosage and schedule of this medication. Taking D-NIB Injection incorrectly or in excessive amounts can lead to serious side effects. Common side effects may include nausea, vomiting, diarrhea, headache, fever, and lung infections. This medication can also lower blood cell counts, making the body more prone to infections. Regular monitoring through blood tests is necessary to evaluate blood cell levels, as well as heart, liver, and blood uric acid levels.
When considering D-NIB Injection, inform your doctor about any existing heart disease, liver or kidney issues, or current medication for infections. Due to potential interactions, it is important to disclose all medications you are taking. Avoid the use of this medication during pregnancy or breastfeeding, and ensure the use of effective contraception by both partners during treatment to prevent pregnancy.
Related lab tests
When evaluating the impact and effectiveness of D-NIB Injection, several related lab tests can provide valuable insights. These tests include Bone Marrow Smear Microscopy Examination, Complete Blood Count (CBC), and Peripheral Smear Examination. A Bone Marrow Smear Microscopy Examination allows for the detailed examination of bone marrow cells under a microscope, providing information on cell composition and detecting any abnormalities. A Complete Blood Count (CBC) gives a comprehensive snapshot of the different types of blood cells present in the body, including red blood cells, white blood cells, and platelets. Additionally, a Peripheral Smear Examination involves scrutinizing a sample of blood under a microscope to assess the size, shape, and number of blood cells, which can help in diagnosing various conditions. These tests play a critical role in monitoring the effects of D-NIB Injection and assessing any potential side effects on the blood and bone marrow.
Additional Information
Habit Forming | No |
Chemical Class | Azacitidine Derivative |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolites |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024