Crinone Tablet
By Crinone
Rx
1 Tablet in a Strip

Composition
Progesterone (Natural Micronized)(NA)

Manufacturer - Merck Ltd
L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Expires on or after
August, 2025
About Crinone Tablet
Crinone Tablet is a medication containing the natural female sex hormone, progesterone. It is commonly used to address menstrual and pregnancy-related issues that stem from hormonal imbalances in the body. This tablet is often prescribed alongside estrogen as part of hormonal replacement therapy to prevent endometrial hyperplasia, which involves the thickening of the uterus lining. It is important to take Crinone Tablet with food, at the same time each day, as directed by your doctor, to maximize its effectiveness. Continuing the medication for the prescribed duration is crucial, even if you are feeling better.
Potential side effects of Crinone Tablet may include headaches, breast pain, irregular vaginal bleeding, stomach cramps, bloating, nausea, hair loss, edema, and vaginal yeast infections. These side effects are more common in the initial weeks of treatment but tend to decrease as your body adjusts to the medicine. If you experience frequent bleeding or spotting between periods, it is advisable to consult your doctor promptly. Prior to starting Crinone Tablet, inform your doctor about any history of breast cancer, unusual vaginal bleeding, or liver disease. Regular monitoring through tests before and during treatment is typical to ensure the medication's efficacy and your well-being. Additionally, be transparent about all other medications you are taking, as some may interact with Crinone Tablet. It is generally recommended to avoid alcohol and smoking while on this medication.
CRINONE 8% GEL, another form of progesterone-containing medication indicated for infertility due to progesterone imbalances during the menstrual cycle or during assisted fertility procedures. This gel form is not recommended for patients with conditions such as unusual vaginal bleeding, cancers of the breast or genital organs, blood clots, porphyria disorder, or missed abortion. Before using CRINONE 8% GEL, inform your doctor about any liver, heart, kidney, or other health issues you may have. Regular evaluations, including smear tests and physical checks, may be necessary during treatment with CRINONE 8% GEL to monitor for any complications. Pregnancy and breastfeeding present specific considerations regarding the use of CRINONE 8% GEL, with caution exercised in these situations.
One common side effect associated with CRINONE 8% GEL is breast tenderness. If this side effect worsens or causes concern, consulting your doctor is recommended.
Benefits
Crinone Tablet provides several benefits for women in hormone replacement therapy and the treatment of female infertility. In hormone replacement therapy, Crinone Tablet is used to alleviate menopausal symptoms such as hot flashes, night sweats, mood swings, vaginal dryness, and reduced sex drive. These symptoms can significantly impact a person's daily life and mood during menopause, which can last for several years. By incorporating progesterone, a crucial hormone alongside estrogen in this treatment, Crinone Tablet aims to address these symptoms effectively. It is essential to follow the prescribed dosage and duration as directed by a healthcare provider, as the medication may not alleviate all symptoms, necessitating consultation with a doctor.
Moreover, in the treatment of female infertility, Crinone Tablet contains progesterone, a key female hormone that plays a vital role in regulating ovulation and menstruation. It is particularly beneficial for women who are not experiencing menstrual periods due to a deficiency of natural progesterone in their bodies. By stimulating menstrual periods and thickening the uterus lining (endometrium), Crinone Tablet helps prepare the uterus for a successful pregnancy, thereby increasing the likelihood of conception. To ensure the effectiveness of the treatment, it is crucial to adhere to the prescribed regimen and continue with the medication for the specified duration, especially after becoming pregnant. Consulting with a healthcare provider for guidance on the appropriate usage of Crinone Tablet is important to optimize the benefits of the drug in hormone replacement therapy and the treatment of female infertility.
How to use the Crinone Tablet
To use Crinone Tablet, it is important to follow your doctor's instructions carefully. Take the tablet in the dose and duration prescribed by your doctor, swallowing it whole with food. Avoid chewing, crushing, or breaking the tablet as this can affect its effectiveness. It is essential to use CRINONE 8% GEL as directed by your physician, specifically for vaginal use only. Before application, ensure to wash the genital area thoroughly. Prepare the applicator and then position yourself comfortably by leaning back or lying down with your knees bent and spread apart. Gently insert the applicator deep into your vagina, up to the point where your hand touches your body. Press the air tank located at the thick end of the applicator firmly to release the gel into your vagina. The dosage and duration of treatment will be determined by your doctor based on your specific condition.
Uses of Crinone Tablet
Crinone Tablet is commonly used for hormone replacement therapy. It is also prescribed to treat female infertility. Hormone replacement therapy involves the administration of hormones to help relieve symptoms related to menopause, such as hot flashes and vaginal dryness. When used to treat female infertility, Crinone Tablet may help support the hormonal environment necessary for a successful pregnancy. This medication plays a crucial role in assisting women with hormonal imbalances to improve their fertility prospects.
What conditions Crinone Tablet treats?
Crinone Tablet is a medication containing progesterone, a female hormone. It is commonly used to address menstrual and pregnancy-related issues stemming from hormonal imbalances. Additionally, it is prescribed in combination with estrogen as part of hormonal replacement therapy to prevent endometrial hyperplasia. The medication should be taken with food at the same time daily for optimal results. Possible side effects include headache, breast pain, vaginal bleeding, abdominal cramps, bloating, nausea, hair loss, edema, and vaginal yeast infections. It is essential to inform your doctor about any medical conditions, previous illnesses, or ongoing medications before taking Crinone. Additionally, alcohol and smoking should be avoided during usage.
Should you consult a doctor?
If you experience any of the following conditions, it is important to consult your doctor before using CRINONE 8% GEL:
- Unexplained vaginal bleeding
- Known or suspected breast or genital cancer
- Blood clot from swollen veins or thromboembolic disorder
- Stroke
- Porphyria disorder
- Missed abortion
Before using CRINONE 8% GEL, ensure to inform your doctor if you have:
- Diabetes
- Migraines
- Seizures
- History of depression.
Side effects of Crinone Tablet
When using Crinone Tablet, you may experience some side effects, but most of them are not severe and may go away as your body gets used to the medication. These side effects include abdominal pain, nausea, abnormal vaginal bleeding, swelling (edema), hair loss, abdominal bloating, headache, breast pain, vomiting, vaginal yeast infection, and breast tenderness. If any of these side effects persist or if you are concerned about them, it is important to consult your doctor. However, if you experience a severe allergic reaction such as an itchy skin rash, you should stop using Crinone 8% Gel immediately and contact your doctor for further evaluation.
Safety advice

liver
Limited information is available about the use of Crinone Tablet in patients with liver disease. It is recommended to consult your doctor for guidance.

kidney
Limited information exists on the use of Crinone Tablet in patients with kidney disease. It is advisable to consult with your doctor regarding its safety for kidney issues.

alcohol
It is uncertain if consuming alcohol with Crinone Tablet is safe. Seek advice from your doctor.

driving
When using Crinone Tablet, be cautious while driving as it can reduce alertness, affect vision, and cause drowsiness and dizziness. Refrain from driving if experiencing these symptoms.

pregnancy
Crinone Tablet is considered safe for use during pregnancy, with studies indicating minimal risk to the baby's development.

breastfeeding
Crinone Tablet is safe to use while breastfeeding. Research shows the drug is unlikely to pass into breastmilk in harmful amounts.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Crinone Tablet
Before consuming Crinone Tablet, it is important to keep in mind certain precautions. This tablet contains progesterone, a natural female sex hormone, and is commonly used to address menstrual and pregnancy-related issues resulting from hormonal imbalances. It is also prescribed in combination with estrogen as part of hormonal replacement therapy to deter endometrial hyperplasia. To optimize its effectiveness, always take Crinone Tablet with food and at the same time each day. Continuous usage is recommended even if you start feeling better.
Although generally well-tolerated, some common side effects may occur, such as headaches, breast pain, stomach cramps, nausea, and vaginal bleeding. These side effects typically diminish as the body adjusts to the medication. Should you experience frequent vaginal bleeding between periods, consult your doctor promptly. Prior to starting this treatment, inform your healthcare provider about any history of breast cancer, unusual vaginal bleeding, or liver disease. Regular medical monitoring is usually necessary during the course of taking these tablets. Moreover, be transparent with your doctor about all the medications you are currently using, as some might interact with Crinone Tablet. It is advisable to refrain from alcohol and smoking while on this medication.
What if you forgot to take Crinone Tablet?
If you forget to take a dose of Crinone Tablet, take it as soon as you remember. But, if it's close to the time for your next dose, then just skip the missed dose and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one. This will help you maintain a consistent level of the medication in your body.
What happens if you take overdose of Crinone Tablet?
If you or someone else uses too much of the CRINONE 8% GEL, it is important to seek immediate medical help. Overdosing on this medication can lead to serious consequences and it is crucial to consult a doctor or go to the nearest hospital as soon as possible.
Related lab tests
Related Lab Tests:
When considering the use of Crinone Tablet, there are several related lab tests that may be important to discuss with your healthcare provider. These tests can provide valuable information about various aspects of your health and how your body may respond to the medication.
1. Anti-Mullerian Hormone: This test measures the level of Anti-Mullerian Hormone in the blood, which can provide insights into ovarian function and fertility potential.
2. Glycosylated Hemoglobin: Also known as HbA1c, this test gives an overview of average blood sugar levels over the past 2-3 months, which is helpful in monitoring and managing diabetes.
3. Testosterone Total: This test measures the total amount of testosterone in the blood, which can be important in assessing hormonal balance, especially in conditions such as low testosterone or androgen excess.
4. Thyroid Stimulating Hormone (TSH): TSH is a hormone that regulates thyroid function, and this test can help evaluate thyroid gland activity, which is crucial for maintaining overall metabolism and energy levels.
These lab tests can provide valuable information to guide treatment decisions and monitor potential side effects or interactions while using Crinone Tablet. It is essential to discuss the necessity and interpretation of these tests with your healthcare provider to ensure optimal management of your health condition.
Additional Information
Habit Forming | No |
Chemical Class | Progesterone Derivative |
Therapeutic Class | GYNAECOLOGICAL |
Action Class | Natural Progesterone |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 11-Feb-2025