Coxibin Plus 450mg/300mg Capsule
By Coxibin Plus
Rx
10 Capsule in a Strip

Composition
Rifampicin(450mg) + Isoniazid(300mg)

Manufacturer - Bindlysh Biotec Ltd
Jhilmil Industrial Area, New Delhi, Delhi

Expires on or after
July, 2026
About Coxibin Plus 450mg/300mg Capsule
Coxibin Plus 450mg/300mg Capsule is a combination medication utilized for treating tuberculosis by inhibiting the growth of the microorganisms responsible for the infection. Being a prescription medicine, it is crucial to adhere to the doctor's recommendations for its intake. It is advised to consume the capsule on an empty stomach at a fixed time to maximize its effectiveness while avoiding exceeding the prescribed dosage to prevent adverse effects on the body. In case of a missed dose, it should be taken promptly, and the full course of treatment must be completed even if symptoms improve, as discontinuing abruptly can impact the medicine's potency. Patience is needed as the medicine may take some time to exhibit its effects on the symptoms, and any worsening or lack of improvement should prompt consultation with the doctor.
Common side effects of Coxibin Plus 450mg/300mg Capsule include nausea, vomiting, fever, dark-colored urine, sweating, and increased saliva. To manage these side effects, adequate hydration is recommended. Should any side effects worsen, immediate medical advice should be sought, although severe side effects are uncommon. Any signs of allergic reactions such as rashes, itching, swelling, or breathing difficulties should be addressed promptly by seeking medical assistance.
Prior to initiating this medication, informing the doctor about ongoing treatments for other health issues is essential. Patients with liver or kidney conditions should take this drug cautiously under proper medical supervision. Pregnant or nursing women should seek the doctor's advice before commencing treatment. Alcohol consumption should be avoided as it may lead to excessive drowsiness. Although the medication typically does not impair driving abilities, caution is advised if it induces drowsiness or dizziness. Adequate rest and a wholesome diet are recommended during treatment for optimal recovery. Periodic laboratory tests may be required by the doctor to monitor the medicine's impact on the body.
Benefits
Coxibin Plus 450mg/300mg Capsule is a powerful combination of medicines specifically designed to combat tuberculosis (TB), which is a serious infectious disease that primarily targets the lungs but can also affect other parts of the body. This medication is effective in both killing and preventing the growth of the bacteria responsible for the infection. By following the prescribed dose and duration recommended by your doctor, Coxibin Plus 450mg/300mg Capsule can significantly help in treating the infection. While your symptoms may start improving during the course of treatment, it is crucial not to discontinue taking the medication without consulting your doctor. Abruptly stopping the medication can lead to a resurgence of the infection or even make it worse. Therefore, it's essential to adhere to your doctor's instructions diligently to ensure you receive the maximum benefits from this medication in combating tuberculosis.
How to use the Coxibin Plus 450mg/300mg Capsule
When using Coxibin Plus 450mg/300mg Capsule, always follow the dose and duration prescribed by your doctor. It is important to take this medicine on an empty stomach for optimal effectiveness. Avoid consuming tyramine-rich foods like cheese, smoked fish, meats, and certain types of beer while taking Coxibin Plus 450mg/300mg Capsule. This will help prevent any potential interactions and ensure the medication works as intended. Be sure to ask your doctor if you have any questions about how to use Coxibin Plus 450mg/300mg Capsule properly.
Uses of Coxibin Plus 450mg/300mg Capsule
Coxibin Plus 450mg/300mg Capsule is primarily used for the treatment of Tuberculosis (TB). It is specifically designed to address the symptoms and underlying causes associated with TB. This medication is an essential component in the management and eradication of tuberculosis, a serious infectious disease that primarily affects the lungs. By targeting the TB bacteria and supporting the body's immune response, Coxibin Plus 450mg/300mg Capsule plays a crucial role in combating the progression of the disease. It is recommended to adhere to the prescribed dosage and duration to effectively treat tuberculosis with this medication.
What conditions Coxibin Plus 450mg/300mg Capsule treats?
Coxibin Plus 450mg/300mg Capsule is utilized in the treatment of tuberculosis, an infectious disease primarily affecting the lungs but can also impact other body parts. It is effective in killing and halting the growth of bacteria causing the infection, aiding in its treatment. Ensure to follow the prescribed dose and duration strictly by your doctor. Improvement in symptoms may occur before complete recovery, so it's crucial not to discontinue treatment abruptly to prevent the infection from returning or worsening. Adhering to your doctor's guidance is essential for optimal results.
Should you consult a doctor?
Seek medical attention if you experience any persistent or concerning side effects while taking Coxibin Plus 450mg/300mg Capsule, such as dark-colored urine, rash, vomiting, jaundice, fever, increased liver enzymes, nausea, or peripheral neuropathy (tingling and numbness of feet and hands). It's essential to consult your doctor if you notice any worsening of your condition or if your symptoms do not improve. Additionally, seek immediate medical help if you have signs of an allergic reaction, such as rashes, itching, swelling, or difficulty breathing. Patients with liver or kidney issues should use this medication cautiously and under proper medical guidance. Pregnant or breastfeeding women should also consult their healthcare provider before using this medicine. In case of any discomfort or unusual reactions, it is advisable to contact your doctor promptly.
Side effects of Coxibin Plus 450mg/300mg Capsule
When taking Coxibin Plus 450mg/300mg Capsule, you may experience some side effects. Most of these side effects are mild and will go away as your body gets used to the medication. It's essential to note that not everyone will experience these side effects. However, if any of the following side effects persist or cause concern, it is crucial to consult your doctor. Some potential side effects include dark colored urine, rash, vomiting, jaundice, fever, increased liver enzymes, nausea, and peripheral neuropathy, which may cause tingling and numbness in your feet and hands. If you have any worries about these side effects, it's best to seek advice from your healthcare provider.
Safety advice

liver
When taking Coxibin Plus 450mg/300mg Capsule, it is important to be cautious if you have liver disease. Patients with liver issues may require a dosage adjustment of Coxibin Plus 450mg/300mg Capsule, so consulting your doctor is necessary. It is not advisable to use Coxibin Plus 450mg/300mg Capsule in individuals with severe liver disease. It is essential to prioritize your liver health and seek medical advice before using this medication if you have liver problems.

kidney
Coxibin Plus 450mg/300mg Capsule requires caution in patients with kidney disease and may need dose adjustment. It is advisable to consult your doctor for proper guidance.

alcohol
Caution Drinking alcohol with Coxibin Plus 450mg/300mg Capsule may lead to reactions like flushing, faster heart rate, nausea, thirst, chest pain, and low blood pressure (Disulfiram reaction).

driving
Coxibin Plus 450mg/300mg Capsule may lead to side effects impacting driving ability including fits, mental health issues, and optic neuritis causing vision loss. It is advisable to exercise caution while driving.

pregnancy
Coxibin Plus 450mg/300mg Capsule may not be safe during pregnancy. Animal studies suggest potential harm to the developing baby. Consult your doctor before using.

breastfeeding
Coxibin Plus 450mg/300mg Capsule is considered safe to use while breastfeeding. Studies show that the drug does not transfer to breastmilk in a harmful amount, posing no risk to the baby.
Consumption warning before consuming Coxibin Plus 450mg/300mg Capsule
Before consuming Coxibin Plus 450mg/300mg Capsule, it is crucial to be aware of certain important factors. This medication is specifically used for treating tuberculosis by inhibiting the growth of harmful microorganisms. It is essential to strictly follow the doctor's prescribed dosage instructions, taking the capsule on an empty stomach at the same time every day for optimal effectiveness. Consuming more than the recommended dose can be harmful to your health. In case of a missed dose, take it as soon as you remember.
Completing the full course of treatment is important even if symptoms improve, as discontinuation abruptly may reduce the medicine's potency. Be patient, as it may take some time for the medicine to show its effects. Monitor for common side effects like nausea, vomiting, and fever. Stay hydrated and seek medical advice if side effects worsen. Serious side effects are uncommon, but seek immediate help if you experience any allergic reactions.
Inform your healthcare provider about all medications you are taking, especially for liver or kidney problems. Pregnant or nursing women should consult a doctor before use. Avoid alcohol, which can intensify drowsiness. While driving ability is usually unaffected, refrain from driving if the medicine causes sleepiness or dizziness. Rest adequately and maintain a nutritious diet for a quicker recovery, and be prepared for diagnostic tests during the course of treatment.
What if you forgot to take Coxibin Plus 450mg/300mg Capsule?
If you forget to take a dose of Coxibin Plus 450mg/300mg Capsule, try to take it as soon as you remember. But if it's close to the time for your next scheduled dose, it's better to skip the missed dose and continue with your usual dosing. Avoid taking a double dose to make up for the missed one. It's important to stick to the recommended dosing schedule for your treatment plan to be effective.
Related lab tests
For patients taking Coxibin Plus 450mg/300mg Capsule, there are several related lab tests that may be necessary to monitor their health and treatment progress. These tests include:
1. Complete Blood Count (CBC): This test helps to assess the overall health of the patient by looking at different components of the blood, such as red blood cells, white blood cells, and platelets.
2. Erythrocyte Sedimentation Rate (ESR): ESR is a blood test that measures inflammation in the body. It can help in detecting conditions such as infections, autoimmune diseases, and certain types of cancer.
3. Mycobacterium Tuberculosis DNA PCR - Qualitative: This test is used to detect the presence of the tuberculosis-causing bacteria in the body. It is especially important for patients taking Coxibin Plus 450mg/300mg Capsule as tuberculosis is a common infection that may require different treatment approaches.
4. Peripheral Smear Examination: This test involves examining a sample of blood under a microscope to look for abnormalities in the size, shape, and number of blood cells. It can help in diagnosing various blood disorders and conditions.
These lab tests are essential for monitoring the patient's health status, detecting any potential complications or side effects from the medication, and ensuring the effectiveness of the treatment. Regularly conducting these tests as advised by the healthcare provider can help in providing comprehensive care to patients taking Coxibin Plus 450mg/300mg Capsule.
Additional Information
| Habit Forming | No |
| Chemical Class | - |
| Therapeutic Class | - |
| Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹54
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024
