Comvac 4 HB Injection
By Comvac 4 HB
Rx
1ml Injection in a Vial

Composition
Diphtheria Toxoid(20LF) + Tetanus Toxoid(5LF) + Pertussis Toxoid(15OU) + Hepatitis B Vaccine (rDNA)(10mcg) + Aluminium Hydroxide(0.3mg)

Manufacturer - Bharat Biotech
Genome Valley Shameerpet, Hyderabad – 500 078 Telagana INDIA

Expires on or after
October, 2025
About Comvac 4 HB Injection
Comvac 4 HB Injection is a combination medication designed to provide protection against diphtheria, tetanus, pertussis, and chronic hepatitis B virus (HBV) infection. By triggering a mild infection, this injection aids in the development of immunity within the body. Through this process, the immune system is stimulated to generate antibodies, essential for safeguarding against potential infections.
Administered exclusively by a medical professional, Comvac 4 HB Injection is typically delivered into the muscle of the anterolateral region of the thigh in infants and young children. It is crucial to note that if you have a known allergy to this injection, it is not advisable to take it. Adherence to the prescribed dosage regimen and strict compliance with your healthcare provider's instructions are imperative to maximize the benefits derived from this medication.
While utilizing Comvac 4 HB Injection, individuals may encounter common side effects such as redness, tenderness, irritability, vomiting, loss of appetite, and fever at the injection site. Should these effects persist or if you experience any other symptoms that you believe may be related to the medication, it is essential to promptly inform your healthcare provider to seek further guidance.
Benefits
Comvac 4 HB Injection offers several key benefits in preventing different serious infections. Firstly, it protects against chronic hepatitis B virus (HBV) infection, which is a liver infection that can lead to severe illness if left untreated. By administering the vaccine to infants and children aged 6 weeks through 6 years, Comvac 4 HB Injection helps shield them from the risks associated with hepatitis B transmission through bodily fluids. Additionally, this injection aids in preventing tetanus, a dangerous bacterial infection that affects the nervous system and causes muscle stiffness. By stimulating the immune system to produce antibodies against tetanus, Comvac 4 HB Injection serves as a crucial defense mechanism. Furthermore, the vaccine provides protection against pertussis, commonly known as whooping cough, which poses a significant health risk to infants and young children. By offering defense against this airway infection, the injection helps in avoiding uncontrollable coughing episodes that can impact breathing. Lastly, Comvac 4 HB Injection guards against diphtheria, a bacterial infection that can lead to throat swelling and breathing difficulties. By ensuring vaccination starting from early infancy up to 6 years, the injection offers a protective shield against the damaging effects of diphtheria on various organs. Overall, Comvac 4 HB Injection plays a vital role in safeguarding individuals from these serious infections and is an important preventive measure recommended in consultation with healthcare providers to ensure optimal vaccination schedules are followed for enduring protection.
How to use the Comvac 4 HB Injection
When it comes to using Comvac 4 HB Injection, it is important to remember that only a qualified healthcare professional, such as your doctor or nurse, should administer this medicine. It is crucial not to try to self-administer this injection. Your healthcare provider will determine the appropriate dosage and administer the injection in a safe and effective manner. Trust in the expertise of your healthcare team to provide you with the necessary care and guidance when using Comvac 4 HB Injection. Remember, always seek professional medical assistance for the administration of this medicine to ensure your safety and well-being.
Uses of Comvac 4 HB Injection
Comvac 4 HB Injection is used for preventing chronic hepatitis B virus (HBV) infection, tetanus, pertussis, and diphtheria. This vaccine is especially important for individuals at risk of these infections. By receiving the Comvac 4 HB Injection, individuals can protect themselves from these diseases.
What conditions Comvac 4 HB Injection treats?
Comvac 4 HB Injection is a combination vaccine used to prevent diphtheria, tetanus, pertussis, and chronic hepatitis B virus (HBV) infection. These diseases can cause serious health issues, from throat pain and breathing difficulties to lifelong liver problems. By initiating a mild infection, this vaccine helps the immune system develop antibodies to protect against future infections. It's crucial for infants and young children to receive this vaccine to prevent these diseases. Consult your healthcare provider for the proper vaccination schedule and any concerns about potential side effects.
Should you consult a doctor?
If you experience side effects such as redness at the injection site, tenderness, irritability, vomiting, loss of appetite, fever, injection site reactions (pain, swelling, redness), headache, body ache, muscle weakness, tiredness, joint pain, or a feeling of discomfort after receiving Comvac 4 HB Injection, and these symptoms persist for an extended period, it is advisable to seek medical attention. While most side effects are temporary and will resolve as your body adjusts to the medication, it is essential to consult your doctor if you are concerned or if the symptoms continue. It is important not to ignore any unusual or prolonged side effects and to follow up with your healthcare provider promptly.
Side effects of Comvac 4 HB Injection
When using Comvac 4 HB Injection, some people may experience side effects, although most of these do not need medical attention and tend to improve as your body gets used to the medication. However, it's important to consult your doctor if these side effects persist or if you are concerned about them. Common side effects of Comvac 4 HB Injection include injection site reactions such as pain, swelling, and redness. You may also experience symptoms such as headache, body ache, muscle weakness, tiredness, joint pain, and a general feeling of discomfort. If you have any concerns about these side effects, be sure to speak with your healthcare provider for guidance.
Safety advice

liver
Limited information is currently available regarding the use of Comvac 4 HB Injection in individuals with liver disease. It is important to consult with your doctor before beginning any treatment with this injection to ensure safety and efficacy. Your doctor will be able to provide you with personalized guidance and advice based on your specific liver condition.

kidney
Limited data exists on using Comvac 4 HB Injection with kidney disease. Consult your doctor.

alcohol
It is not clear if it is safe to drink alcohol while using Comvac 4 HB Injection. Consult your doctor.

driving
It is not clear if Comvac 4 HB Injection affects driving abilities. Refrain from driving if you have symptoms that impair focus and reaction time.

pregnancy
Safety advice regarding the use of Comvac 4 HB Injection during pregnancy is not available. Please consult your doctor.

breastfeeding
It is better to consult your doctor before using Comvac 4 HB Injection during breastfeeding.
Consumption warning before consuming Comvac 4 HB Injection
Prior to consuming Comvac 4 HB Injection, it is important to note that this medication is a combination vaccine primarily used to safeguard against diphtheria, tetanus, pertussis, and chronic hepatitis B virus infection. By introducing a mild infection, it aids in developing immunity and prompting the production of antibodies by the immune system for future protection. The injection should only be administered by a trained healthcare provider, typically in the thigh muscle of infants and young children. Individuals with known allergies to the components of the vaccine should refrain from taking it. Adhering to the prescribed dosage schedule is crucial for optimal effectiveness. Common side effects may include redness, tenderness at the injection site, irritability, vomiting, loss of appetite, and fever. Should any of these side effects persist or if you experience new symptoms that you suspect may be related to the vaccine, it is imperative to promptly inform your healthcare provider.
Related lab tests
Related Lab Tests for Comvac 4 HB Injection include:
1. Complete Blood Count (CBC): This test is used to measure various components of the blood such as red blood cells, white blood cells, and platelets. It can help in assessing overall health and detecting any potential issues related to blood disorders or infections.
2. Hepatitis B (Core) IgM Antibody Test: This test is used to detect the presence of IgM antibodies specific to the core antigen of the Hepatitis B virus. It is helpful in diagnosing acute Hepatitis B infection.
3. Hepatitis B s (Surface) Antigen Test: This test is used to detect the presence of the Hepatitis B surface antigen in the blood. A positive result indicates an active Hepatitis B infection, while a negative result may suggest either immunity or absence of the virus.
4. Hepatitis C Virus Total Antibody Test: This test is used to detect the presence of antibodies against the Hepatitis C virus in the blood. It can help in diagnosing both acute and chronic Hepatitis C infections.
These lab tests are important in assessing the immune response to Hepatitis B and C viruses, as well as monitoring for potential infections or complications that may arise after receiving the Comvac 4 HB Injection.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | - |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹125
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 11-Feb-2025