Capnea Solution

By Capnea

1ml Oral Solution in a Bottle

Composition icon

Composition

Caffeine(20mg)

Manufacturer - Cipla Ltd icon

Manufacturer - Cipla Ltd

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Expires on or after icon

Expires on or after

May, 2026

About Capnea Solution

Capnea Solution is a prescription medication used to treat apnea in premature newborns, a condition where breathing repeatedly stops and starts. It helps in normalizing breathing patterns and reducing interrupted breathing episodes in newborns. This medication is administered under the supervision of healthcare professionals and can be given orally or through a gastric feeding tube. If a mother is breastfeeding while her infant is on this medication, it is advised to avoid consuming coffee or other high-caffeine products as caffeine can pass into breast milk.

The active ingredient in Capnea Solution, Caffeine Citrate, belongs to a group of medicines called methylxanthines and acts as a CNS stimulant. It works by blocking adenosine receptors, inhibiting phosphodiesterase, and mobilizing intracellular calcium. These actions collectively stimulate the respiratory center, making it more sensitive to carbon dioxide levels. This effectively regulates respiratory rate, improves blood flow in the lungs, reduces carbon dioxide sensitivity, and enhances breathing function in premature infants.

Capnea Solution should be used as prescribed by a doctor, who will determine the appropriate dosage based on the infant's medical condition. While generally well-tolerated, some potential side effects of this medication include restlessness, insomnia, headaches, dizziness, and increased heart rate. If these side effects persist or worsen, it is important to consult with a healthcare provider for advice on managing or reducing them.

It is important to inform the doctor about the infant's complete medical history before starting Capnea Solution. This medication should be used with caution in infants with impaired liver or kidney function. Prior to determining the dosage, baseline serum caffeine levels may be assessed, especially in infants born to mothers who consume caffeine. Additionally, Capnea Solution is also used to treat and prevent bronchopulmonary dysplasia in premature infants. Consulting a healthcare professional is crucial if the infant has any underlying health conditions like liver, kidney, or heart problems, seizure disorders, slow weight gain, or frequent regurgitation.

For mothers nursing infants receiving Capnea Solution treatment, avoiding high-caffeine products is essential to prevent overdosage risks. The most common side effect of this medication is a fast or irregular heartbeat, and any concerning symptoms should be discussed promptly with a healthcare provider.


Benefits

Capnea Solution, containing Caffeine Citrate, offers various benefits due to its unique composition. Caffeine Citrate, classified as a central nervous system stimulant, functions in multiple ways. Firstly, it acts as an adenosine receptor antagonist, disrupting the neurotransmitter that promotes sleep and relaxation. Secondly, it works as a phosphodiesterase inhibitor, aiding in improving respiratory function by relaxing smooth muscle and dilating bronchioles. Lastly, it serves as an active intracellular calcium mobilizer, contributing to the stimulation of the respiratory center. Together, these actions effectively regulate the mean respiratory rate and tidal volume, enhancing pulmonary blood flow, reducing sensitivity to carbon dioxide, and improving diaphragmatic function and breathing pattern. Overall, Capnea Solution 1ml proves to be beneficial in sensitizing the respiratory center to hypercapnia, thereby improving respiratory function and overall pulmonary health for patients in need.


How to use the Capnea Solution

To use Capnea Solution, follow your doctor's instructions carefully. Before using, always check the label for directions. Use a measuring cup to ensure the correct dose. Shake the bottle well before use. You can take Capnea Solution with or without food, but it's best to take it at the same time each day.

For children, Capnea Solution 1ml should be used as prescribed by the doctor. A healthcare professional, such as a doctor or nurse, will administer Capnea Solution orally to your child via a gastric feeding tube. The proper dose and duration of therapy will be determined by the doctor based on your child's gestational age, weight, and overall health condition. It is important to follow these instructions carefully to ensure the safe and effective use of Capnea Solution for your child's treatment.


Uses of Capnea Solution

Capnea Solution is primarily used for premature newborns or neonates experiencing primary apnea. This medication effectively treats episodes of interrupted breathing in premature babies, helping to address the underlying cause of this condition. Additionally, Capnea Solution is also utilized to treat and prevent bronchopulmonary dysplasia in premature infants, a condition that causes damage to the airways. By administering Capnea Solution, healthcare providers can manage primary apnea and reduce the risk of bronchopulmonary dysplasia in vulnerable premature babies.


What conditions Capnea Solution treats?

Apnea is a condition characterized by a pause in breathing which can lead to changes in heart rate and oxygen levels. This is often seen in premature infants due to the immaturity of their central nervous system. Other factors like metabolic issues can also contribute to the occurrence of apnea.


Should you consult a doctor?

If your baby experiences fits, frequent regurgitation, increased urination, slow weight gain, increased caffeine intake by the mother before birth, or use of antiepileptic medicines during pregnancy, consult a doctor before administering Capnea Solution. These conditions can impact the baby's health and may require medical attention. It's important to communicate any relevant information about your baby's health history to the doctor to ensure safe and effective treatment.


Side effects of Capnea Solution

When taking Capnea Solution, you may experience some side effects. These side effects are usually mild and may go away as your body gets used to the medicine. Some common side effects include restlessness, headache, dizziness, increased heart rate, and difficulty sleeping. In some cases, you may also notice tachycardia (fast heartbeat), hyperglycemia (increased sugar in the blood), or arrhythmia (irregular heartbeat). If you or your child experience severe side effects such as bloody stools, fits, blood infections, or allergic reactions like skin rash, itching, swelling of the face, lips, or tongue, or difficulty breathing, it is important to contact your doctor immediately. It is crucial to consult your healthcare provider if you have any concerns about these side effects or if they persist.


Safety advice

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liver

Caution should be exercised when using Capnea Solution in patients with liver disease. It is important to consult with your doctor before using this solution if you have any liver-related issues. Limited information is available regarding the safety of Capnea Solution in individuals with liver disease, so seeking medical advice is crucial to ensure safe usage.

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kidney

Consult with your doctor for proper guidance before using Capnea Solution.

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alcohol

It is not safe to drink alcohol while taking Capnea Solution. Mixing alcohol with this medication can be harmful. Please avoid alcohol consumption while using Capnea Solution. Consult your doctor when consuming alcohol with Capnea Solution.

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driving

When using Capnea Solution, it can lower alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these symptoms for safety.

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pregnancy

Capnea Solution may not be safe for use during pregnancy. Limited human studies and animal studies suggest potential harm to the developing baby. Consult your doctor for a careful evaluation of benefits and risks before considering its use.

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breastfeeding

During breastfeeding, it is advisable to use Capnea Solution cautiously. It is recommended to pause breastfeeding until the mother's treatment is finished and the drug is cleared from her system.


Age below 6 months(Pediatrics)

Capnea Solution can be used in premature infants born between 28-33 gestation weeks (7-8 months of pregnancy) under careful medical supervision.

Consumption warning before consuming Capnea Solution

Before giving Capnea Solution to your infant, inform your doctor about their medical history. If your infant is being treated with this medication and you are breastfeeding, avoid consuming coffee or any other caffeine-containing products because caffeine can pass into breast milk. Capnea Solution 1ml is meant to be used only in a neonatal intensive care unit where there are proper patient surveillance and monitoring facilities. Treatment should start under the guidance of a neonatologist who has experience in neonatal intensive care. Use this medication carefully in infants with liver or kidney issues.


What happens if you take overdose of Capnea Solution?

Overdose with Capnea Solution is unlikely as it is given by healthcare professionals in a hospital setting. However, it is important to watch for signs like fits or other side effects in children and promptly consult a doctor if any concerns arise. This helps ensure that proper steps can be taken to address any potential issues and maintain the safety and well-being of the patient.


Additional Information

Habit FormingNo
Chemical ClassXanthine Derivative
Therapeutic Class-
Action ClassAdenosine receptor (A1 & A2) antagonist

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

275.15

Inclusive of all taxes

Content verified by

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025