Bryxta 300 Injection

By Bryxta

Rx

12ml Injection in a Vial

Composition icon

Composition

Bevacizumab(300mg)

Manufacturer - Zydus Cadila icon

Manufacturer - Zydus Cadila

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after icon

Expires on or after

May, 2026

About Bryxta 300 Injection

Bryxta 300 Injection is a potent anticancer medication widely used to combat various types of cancers affecting the colon, rectum, lung, kidney, brain, ovarian, and cervical regions. By inhibiting the growth of new blood vessels that nourish tumors, it effectively halts tumor progression. When integrated with other cancer drugs, Bryxta 300 Injection emerges as a primary treatment choice. It is administered via infusion, either through a vein using a small needle or through an implanted port under the skin. The dosage and duration of Bryxta 300 Injection are carefully determined by your healthcare provider, who will monitor for infusion reactions like elevated blood pressure and breathing difficulties. Treatment continues as long as the disease remains under control and side effects remain manageable, with adjustments made as necessary.

Potential side effects of Bryxta 300 Injection include rectal bleeding, taste alterations, and headaches. Patients are advised to inform their doctor before undergoing any surgical procedures, as the medication can interfere with wound healing and increase the risk of bleeding. Immediate medical attention is necessary if unusual bleeding occurs. Regular monitoring of blood pressure and urine protein levels may be recommended while on this treatment. Special caution is advised for pregnant or breastfeeding individuals, with effective contraception use suggested during treatment and for six months following the final dose. Bryxta 300 Injection is not to be self-administered and should only be administered by a healthcare professional.

The key component in Bryxta 300 Injection 12 ml is Bevacizumab, a monoclonal antibody that targets vascular endothelial growth factor (VEGF) located on blood and lymph vessel linings. By inhibiting VEGF, the drug restricts the growth of blood vessels within tumors, thereby limiting oxygen and nutrient supply, causing tumor regression. Side effects such as loss of appetite, constipation, fever, nosebleeds, speech changes, and taste alterations may occur, but most of these effects resolve on their own. Patients are advised to avoid driving due to potential drowsiness and fainting. Breastfeeding is contraindicated while on Bryxta 300 Injection and for six months post-treatment. Regular communication with healthcare providers regarding medical conditions and concurrent medications is essential to mitigate potential adverse reactions.


Benefits

Bryxta 300 Injection is a valuable medication with various benefits in treating different types of cancer. In cases of colon and rectum cancer, also known as colorectal cancer, Bryxta 300 Injection effectively treats the disease by targeting cancer cells and reducing the risk of further growths. It works by preventing the multiplication of cancer cells, thus hindering the advancement of the disease. This injection is crucial in managing symptoms like blood in the stool, changes in bowel movements, weight loss, and fatigue associated with colorectal cancer. It is important to consult with your doctor about the potential risks and benefits of using this medication due to its potency and toxicity.

Additionally, Bryxta 300 Injection is beneficial in treating non-small cell lung cancer, which affects both smokers and non-smokers. When used alone or in combination with other medicines, this injection effectively targets cancer cells to stop their growth. To maximize the benefits of treatment, it is advised to abstain from alcohol and smoking, while staying adequately hydrated by drinking plenty of water. Similarly, in the case of kidney cancer, Bryxta 300 Injection plays a crucial role in addressing symptoms such as blood in the urine, back pain, weight loss, and fatigue. By halting cancer growth and preventing cell multiplication, this medication helps restrict the spread of cancer to other areas.

Furthermore, Bryxta 300 Injection is also beneficial in the treatment of brain tumors, ovarian cancer, and cervical cancer. In brain tumor cases, this medication effectively kills cancer cells and hinders their multiplication. For ovarian cancer, where early detection is often challenging, Bryxta 300 Injection can be instrumental in halting cancer progression and preventing cell growth. In cervical cancer, this anti-cancer medicine targets cancerous cells in the cervix, providing relief from symptoms such as abnormal bleeding and lower back pain.

Overall, Bryxta 300 Injection containing Bevacizumab, a monoclonal antibody, is a potent tool in the fight against various cancers. By inhibiting the protein vascular endothelial growth factor (VEGF), this medication limits the oxygen and nutrient supply to tumor cells, leading to their shrinkage or cessation of growth. It is essential to have detailed discussions with your healthcare provider to understand the risks and benefits associated with Bryxta 300 Injection, given its effectiveness and potential side effects.


How to use the Bryxta 300 Injection

When using Bryxta 300 Injection, it is important to remember that only a healthcare professional should administer this medication. The injection comes in a 12 ml vial, and it should not be self-administered. Your doctor or nurse will be responsible for giving you the injection, so it is important to follow their instructions carefully. Do not attempt to use this medicine on your own. Always rely on the guidance and expertise of a trained healthcare provider when using Bryxta 300 Injection to ensure its safety and effectiveness for your treatment.


Uses of Bryxta 300 Injection

'Bryxta 300 Injection' is a medication used in the treatment of various types of cancers such as cancer of the colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian cancer, and cervical cancer. It is particularly effective in managing metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, and cancer of the colon and rectum. This injection plays a crucial role in targeting these specific types of cancer, providing patients with a promising treatment option to help fight against these aggressive diseases.


What conditions Bryxta 300 Injection treats?

Cancer is a serious condition where cells in a particular area of the body grow and multiply uncontrollably. These cancerous cells can invade nearby healthy tissues and organs, leading to damage. Cancer can start in one part of the body and spread to other areas. The main cause of cancer is mutations in genes that control cell growth, causing the cells to divide rapidly and form tumors. Treatment options for cancer include surgery, chemotherapy, radiotherapy, stem cell transplantation, immunotherapy, and targeted drug therapy.


Should you consult a doctor?

If you experience any of the following symptoms while using Bryxta 300 Injection: rectal bleeding, taste change, headache, nosebleeds, back pain, dry skin, high blood pressure, protein in urine, or inflammation of the nose, it is important to seek medical attention promptly. Additionally, inform your doctor if you notice any unusual bleeding, as Bryxta 300 Injection can increase the risk of bleeding. Consult your healthcare provider before any surgical procedure due to the medication's effect on wound healing. It is crucial to notify your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Bryxta 300 Injection may have implications. Since this medicine can interact with other medications, inform your healthcare team about all the medicines you are taking. Remember, most side effects lessen as your body adapts, but consult your doctor if concerns persist.


Side effects of Bryxta 300 Injection

When using Bryxta 300 Injection, you may experience some side effects, although most of them are not serious and tend to fade as your body gets used to the medication. Common side effects include rectal bleeding, taste change, headaches, and nosebleeds. Other possible side effects are back pain, dry skin, high blood pressure, and the presence of protein in the urine. In some cases, you may also notice inflammation of the nose, constipation, loss of appetite, or fever. Additionally, nosebleeds, changes in speech or taste, voice changes or hoarseness, and unintended weight loss are potential side effects to be aware of when using Bryxta 300 Injection. If any of these side effects persist or cause concern, it is advisable to consult your doctor for further guidance.


Safety advice

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liver

When it comes to liver issues, Bryxta 300 Injection appears to be safe for use in patients with liver disease based on the available data. It is indicated that adjusting the dose of Bryxta 300 Injection may not be necessary for these individuals. It is advisable to seek guidance from your doctor in this regard.

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kidney

Bryxta 300 Injection is considered safe for patients with kidney disease. Available data indicates dose adjustment may not be necessary. Consult your doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Bryxta 300 Injection.

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driving

Bryxta 300 Injection may cause sleepiness and fainting, affecting driving ability. Exercise caution as impairments have been reported.

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pregnancy

Bryxta 300 Injection may not be safe during pregnancy. Limited human studies suggest potential harm to the developing baby based on animal studies. Your doctor will assess risks and benefits before prescribing. Consult your doctor before use.

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breastfeeding

Bryxta 300 Injection is not recommended during breastfeeding as it may pass into breastmilk, potentially harming the baby. It is best to consult a doctor prior to using this medication while breastfeeding.


Consumption warning before consuming Bryxta 300 Injection

Before consuming Bryxta 300 Injection 12 ml, it is important to note the following precautions for your safety and well-being. Always take this medication under the supervision of a medical professional who will regularly monitor your condition. Inform your doctor if you have a history of allergic reactions to Bryxta 300 Injection 12 ml or other medications. It is advised to avoid taking this injection if you are pregnant, and to use effective contraception during treatment and for 6 months after the last dose. Bryxta 300 Injection 12 ml may cause drowsiness and fainting, so refrain from driving while on this treatment. Inform your doctor about any prior medical conditions, surgeries within the past 28 days, or upcoming surgeries. Avoid breastfeeding during the treatment and for 6 months post-treatment. Additionally, do not receive any immunizations or vaccinations without approval from your doctor. Be vigilant for any signs of bleeding or bruising as Bryxta 300 Injection 12 ml may increase the risk of bleeding.


Disease interactions

When discussing potential disease drug interactions with Bryxta 300 Injection, it is crucial to inform your healthcare provider if you have a history of infections, bleeding disorders, fistula formation, GI perforation, hypertension, PRES (Posterior Reversible Encephalopathy Syndrome), proteinuria, or thromboembolic disorders. These conditions may interact with the medication and affect its effectiveness or increase the risk of adverse reactions. It is important to always disclose all relevant medical information to your doctor before starting treatment with Bryxta 300 Injection to ensure safe and optimal use of the medication.


What if you forgot to take Bryxta 300 Injection?

If you happen to miss a dose of Bryxta 300 Injection, it is crucial to consult your doctor promptly. It is important to adhere to the prescribed schedule to ensure the effectiveness of the treatment. Your doctor will be able to provide guidance on how to proceed and whether any adjustments need to be made. Seeking medical advice in such situations is vital to maintain the optimal management of your condition.


Related lab tests

When considering the related lab tests for Bryxta 300 Injection, it is important to recognize the significance of monitoring certain factors to ensure the safety and efficacy of the treatment. The following lab tests are commonly recommended in relation to Bryxta 300 Injection:

1. Carcino Embryonic Antigen (CEA) Test: This test is used to measure the levels of CEA in the blood, which can be elevated in certain types of cancer. Monitoring CEA levels can be helpful in assessing response to treatment and disease progression.

2. Complete Blood Count (CBC): A CBC test provides important information about the various types of cells in the blood, such as red blood cells, white blood cells, and platelets. Regular CBC tests can help detect any abnormalities or side effects of Bryxta 300 Injection on the blood cells.

3. Human Papilloma Virus (HPV) Test: This test is used to detect the presence of HPV, a common sexually transmitted infection that can lead to various health issues, including cervical cancer. For individuals receiving Bryxta 300 Injection, HPV testing may be recommended as part of routine screening.

4. Papanicolaou (PAP) Cytology Test: Also known as a Pap smear, this test is used to screen for cervical cancer and other abnormalities in the cervix. Regular PAP cytology tests are essential for monitoring the cervical health of individuals undergoing treatment with Bryxta 300 Injection.

By conducting these related lab tests in conjunction with Bryxta 300 Injection therapy, healthcare providers can obtain valuable information about the patient's overall health status, response to treatment, and potential risks associated with the medication. Regular monitoring through these lab tests can help ensure optimal care and management of the individual's condition.


Additional Information

Habit FormingNo
Chemical ClassMonoclonal Antibody
Therapeutic Class-
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025