Bretolap Tablet

By Bretolap

Rx

30 Tablet in a Bottle

Composition icon

Composition

Lapatinib(250mg)

Manufacturer - Alkem Laboratories Ltd icon

Manufacturer - Alkem Laboratories Ltd

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after icon

Expires on or after

June, 2026

About Bretolap Tablet

Bretolap Tablet is a medication used in the treatment of breast cancer. It functions by halting or slowing down the growth of cancer cells in the body. This tablet can be taken either on an empty stomach or at least an hour prior to eating or two hours after a meal. The dosage and duration of treatment vary depending on the severity of the condition and individual response to the medicine. It is crucial to follow the prescribed dosage to prevent any adverse effects. While the benefits may take some time to be noticeable, it is important not to discontinue the medication without your doctor's advice.

Common side effects of Bretolap Tablet include nausea, headache, back pain, and difficulty in breathing. In some cases, it may lead to severe diarrhea, for which it is advisable to drink plenty of fluids or consult your doctor. Regular monitoring of blood pressure may be required while using this medicine. It is essential to notify your doctor if you experience severe symptoms such as headache, confusion, vision issues, nausea, or vomiting. Moreover, liver function tests may be conducted before, during, and after the treatment with Bretolap Tablet.

Before starting Bretolap Tablet, inform your doctor about any existing liver or kidney problems. It is important to disclose all medications you are currently taking, as various drugs can interact with Bretolap Tablet. This medicine is not recommended during pregnancy or breastfeeding, necessitating the use of effective contraception by both partners to prevent pregnancy.

Bretolap 250 mg Tablet 30's is an anti-cancer medication specifically used in the treatment of breast cancer. It is often administered in combination with other drugs to target specific types of breast cancer. The active ingredient in Bretolap 250 mg Tablet 30's is Lapatinib, a kinase inhibitor that works by inhibiting the production of the HER2 protein, thereby impeding the growth of cancer cells and promoting apoptosis.

Side effects of Bretolap 250 mg Tablet 30's may include diarrhea, fatigue, nausea, rash, indigestion, loss of appetite, headache, vomiting, weakness, and others. Most of these side effects are mild and tend to resolve over time. However, if they persist, it is recommended to consult with your healthcare provider. It is crucial to take Bretolap 250 mg Tablet 30's as directed by your doctor and avoid missing doses. Prior to starting treatment, discuss your medical history, including any cardiovascular conditions or liver/kidney diseases, with your healthcare provider. This medicine is known to pose risks to the embryo and fetus, so it is important to inform your doctor if you are pregnant or breastfeeding before initiating treatment.


Benefits

Bretolap Tablet offers significant benefits in the treatment of breast cancer. It is effective in treating breast cancer either alone or in combination with other treatments like chemotherapy. The medication helps alleviate common symptoms of breast cancer such as breast lumps, abnormal discharge from nipples, or changes in breast texture. Bretolap Tablet functions by halting the growth of cancerous cells and works to prevent their multiplication.


Specifically, the tablet includes Lapatinib as its active ingredient, which, when combined with capecitabine, is utilized for patients with HER2-positive advanced or metastatic breast cancer who have undergone prior treatments. Lapatinib functions by targeting the excess production of the human epidermal growth factor receptor 2 (HER2) protein in mammalian cells, which plays a crucial role in inhibiting the growth of cancer cells and ultimately triggering apoptosis, or the natural death of these cells.


It is advisable to consult your healthcare provider if you experience any side effects while taking Bretolap Tablet.


How to use the Bretolap Tablet

To use Bretolap Tablet correctly, follow your doctor's instructions on the dosage and duration. Take the tablet whole and do not chew, crush, or break it. It is important to take Bretolap Tablet on an empty stomach. Swallow the tablet with a full glass of water, either one hour before or at least one hour after a meal as prescribed by your doctor. This medication should be taken as directed to ensure its effectiveness. Remember to always consult your doctor for proper guidance on the usage of Bretolap Tablet.


Uses of Bretolap Tablet

Bretolap Tablet is used for the treatment of breast cancer. It is an effective medication recommended by healthcare professionals for managing breast cancer. The medication helps in combating the growth and spread of cancer cells in the breast. It is important to follow the prescribed dosage and frequency as directed by your doctor to achieve the best results in treating breast cancer.


What conditions Bretolap Tablet treats?

Breast cancer is a type of cancer that happens when cells in the breast start to grow abnormally. This can occur in different parts of the breast, like the glands that produce milk, the ducts that carry milk to the nipple, or the fatty and connective tissues in the breast. Common symptoms include a lump in the breast, breast pain, redness, swelling, unusual nipple discharge, lumps under the arm, and changes in breast shape or appearance. It is important to be aware of these signs and seek medical attention if any symptoms are noticed.


Should you consult a doctor?

If you experience severe side effects such as breathing problems, severe diarrhea, or liver damage while taking Bretolap Tablet, it is important to seek medical attention promptly. Additionally, if you notice symptoms like a severe headache, confusion, or problems with your eyesight, it is essential to consult your doctor immediately. Regular monitoring of blood pressure and liver function may be necessary, so inform your doctor of any changes or concerns. If common side effects like nausea or headache persist or worsen, or if you have any other worries about your symptoms, do not hesitate to reach out to your healthcare provider for guidance. Remember to disclose any existing liver or kidney issues and all medications you are taking to ensure safe usage of Bretolap Tablet.


Side effects of Bretolap Tablet

When taking Bretolap Tablet, you may experience some side effects. These effects are usually mild and may go away as your body gets used to the medication. However, if they persist or if you are concerned, it is important to consult your doctor. Common side effects of Bretolap Tablet include abdominal pain, back pain, breathing problems, constipation, cough, diarrhea, fatigue, headache, hot flashes, increased bilirubin in the blood, insomnia (difficulty in sleeping), joint pain, liver damage, loss of appetite, mucosal inflammation, nausea, pain in extremities, rash, stomatitis (inflammation of the mouth), vomiting, weakness, and weight gain. Additionally, some users may also experience nausea, vomiting, diarrhea, myalgia, dry skin, hair loss, tiredness, weakness, headache, and fatigue. It is essential to monitor these side effects and seek medical advice if needed.


Safety advice

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liver

Caution should be taken when using Bretolap Tablet in individuals with liver disease. It may be necessary to adjust the dosage of the tablet in such cases. It is advised to consult with your doctor before using Bretolap Tablet, especially for patients with severe liver disease as there is limited information available on its use in this particular condition.

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kidney

Caution should be taken when using Bretolap Tablet in patients with severe kidney disease as dose adjustment may be necessary. Consult your doctor as limited information is available for this group. No dose adjustment is needed for patients with mild to moderate kidney disease.

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alcohol

Consult your doctor when consuming alcohol with Bretolap Tablet.

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driving

When taking Bretolap Tablet, be cautious while driving, as it may cause side effects that can impact your driving ability.

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pregnancy

Bretolap Tablet is not safe for use during pregnancy due to potential risk to the developing baby. Consult your doctor before use, as they may only prescribe it in life-threatening situations if benefits outweigh risks.

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breastfeeding

Caution should be taken during breastfeeding, as Bretolap Tablet is considered unsafe due to potential toxicity to the baby. It is better to consult your doctor before using Bretolap Tablet.


Consumption warning before consuming Bretolap Tablet

Before taking Bretolap Tablet, make sure you are not allergic to it or any of its components. Notify your doctor about any heart conditions or liver/kidney issues, as this medicine can have negative effects. During the treatment, watch for left ventricular ejection fraction, prolonged QT interval, and other possible reactions like liver problems, lung issues, severe diarrhea, and hypersensitivity responses. If any changes or reactions occur, stop the treatment immediately. Bretolap Tablet can harm unborn babies, so inform your doctor if you are pregnant or planning to conceive. Nursing mothers should not breastfeed while taking this medicine. This medication is not suitable for children unless prescribed by a pediatrician due to uncertain safety and efficacy in this age group. Avoid alcohol and smoking to prevent severe side effects.


Disease interactions

When taking Bretolap Tablet, make sure to inform your doctor if you have any cardiac issues, lung disease, or liver/kidney problems. It is important to disclose these conditions to ensure safe use of the medication and to avoid any potential interactions that could affect its effectiveness or your health. By being transparent about your medical history, your doctor can provide appropriate guidance on how to manage any disease-drug interactions that may arise while taking Bretolap Tablet.


What if you forgot to take Bretolap Tablet?

If you forget to take a dose of Bretolap Tablet, it is important to consult your doctor promptly. It is recommended not to double the dose to make up for the missed one. Your doctor will provide guidance on the best course of action to take if you have missed a dose of Bretolap Tablet. Regular and timely intake of this medication is crucial for its effectiveness, so it is essential to address any missed doses promptly.


Related lab tests

For patients taking Bretolap Tablet, there are certain related lab tests that may be recommended to monitor their health. These tests are specifically related to Breast Cancer and include CA 15.3, ER (Estrogen Receptor), and PR (Progesterone Receptor) tests. The CA 15.3 test measures the levels of a protein that may be elevated in some cases of Breast Cancer. The ER and PR tests determine if the breast cancer cells have receptors for estrogen and progesterone, which can help guide treatment decisions. Monitoring these lab tests can be important in managing Breast Cancer and assessing the effectiveness of treatment.


Additional Information

Habit FormingNo
Chemical ClassQuinazolinamines Derivative
Therapeutic ClassANTI NEOPLASTICS
Action ClassTyrosine kinase inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024