Bosentan 125 Tablet

By Bosentan

Rx

10 Tablet in a Strip

Composition icon

Composition

Bosentan(125mg)

Manufacturer - Care Formulation Labs Pvt Ltd icon

Manufacturer - Care Formulation Labs Pvt Ltd

D-1659, DSIIDC, Narela Industrial Area, Delhi, 110040

Expires on or after icon

Expires on or after

August, 2025

About Bosentan 125 Tablet

Bosentan 125 Tablet is a prescribed medication primarily used to address pulmonary arterial hypertension, a condition characterized by high pressure in the blood vessels that transport blood from the heart to the lungs. This medicine is designed to not only help manage this condition but also to enhance overall quality of life, increase exercise capacity, and potentially slow down the progression of the disease.

When taking Bosentan 125 Tablet, it is advisable to follow the prescribed dosage, whether with or without food. Consistent and regular intake is crucial to derive the maximum benefits from this medication. The specific dosage and frequency of administration will be determined by your healthcare provider based on your individual requirements to alleviate symptoms effectively. It is important to continue taking the medicine as directed by your doctor.

Like any medication, Bosentan 125 Tablet may lead to certain side effects, the most common being headache, leg and ankle swelling, and diarrhea. If these side effects become bothersome or severe, it is essential to inform your healthcare provider. Additionally, some more serious adverse effects, such as anemia (low red blood cell count) and abnormal liver function, require immediate medical attention. Symptoms of abnormal liver function may include nausea, vomiting, dark urine, fever, and yellowing of the skin or eyes. Regular blood tests may be recommended by your doctor to monitor for these potential side effects.

Prior to starting Bosentan 125 Tablet, it is crucial to inform your healthcare provider if you have any existing liver conditions. Pregnant or breastfeeding individuals should also notify their doctor before taking this medication. Women of childbearing age are advised to use reliable contraceptive methods to prevent pregnancy while using this medication, and this practice should be continued for at least one month after treatment cessation. It is also essential to disclose all other medications you are currently taking, as some of them may interact with Bosentan 125 Tablet, potentially reducing its efficacy or altering its mechanism of action.


Benefits

Bosentan 125 Tablet is a medication that offers several benefits for individuals with pulmonary arterial hypertension (PAH). This condition can lead to various symptoms such as shortness of breath, tiredness, dizziness, chest pain, and swelling in the ankles and legs. The thickening of the arteries supplying the lungs can make it difficult for blood to flow through, resulting in high blood pressure in the lung arteries.

By taking Bosentan 125 Tablet, the blood vessels relax, which helps to lower the blood pressure in the arteries of the lungs. This effect allows individuals to engage in their daily activities more comfortably, experience less fatigue and dizziness, and improve their overall quality of life. Moreover, Bosentan 125 Tablet works by blocking the action of endothelin, a substance that narrows blood vessels and increases pressure in the vessels of the lungs. By blocking endothelin, this medication helps relax the blood vessels and increase blood supply to the lungs.

Overall, the benefits of Bosentan 125 Tablet include improving exercising ability, delaying disease progression, and enhancing quality of life for individuals with pulmonary arterial hypertension. By effectively managing the condition and addressing its symptoms, this medication plays a crucial role in helping patients lead a more comfortable and active life.


How to use the Bosentan 125 Tablet

To use Bosentan 125 Tablet correctly, follow your doctor's instructions on the dosage and duration of treatment. Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet. You can take Bosentan 125 Tablet with or without food, but try to take it at the same time each day for better consistency. If you are prescribed Bosentan 125 Tablet tablets for oral suspension, carefully read the label for directions. Disperse the tablet in the specified amount of water as indicated and swallow the mixture. Remember not to crush, chew, or swallow the tablet whole. Your physician will determine the appropriate dose and duration based on factors like your age, weight, and medical condition. Be sure to follow their guidance for the best results.


Uses of Bosentan 125 Tablet

Bosentan 125 Tablet is used to treat pulmonary arterial hypertension (PAH). PAH is a condition where the blood vessels in the lungs become narrow, making it harder for the heart to pump blood through them. This medication helps to widen the blood vessels, allowing the blood to flow more easily. Bosentan 125 Tablet is also used to treat digital ulcers in individuals affected by scleroderma. Scleroderma is a condition that causes the skin and tissues to harden and tighten, leading to the development of digital ulcers. By improving blood flow, Bosentan 125 Tablet can help heal these ulcers and provide relief to those affected by scleroderma.


What conditions Bosentan 125 Tablet treats?

Bosentan 125 Tablet is used to treat Pulmonary Arterial Hypertension (PAH). PAH is a condition where there is high pressure in the blood vessels that carry blood from the heart to the lungs. This high pressure can be caused by the narrowing or blockage of these blood vessels. Bosentan 125 Tablet helps in managing the symptoms and complications associated with PAH.


Should you consult a doctor?

Before taking Bosentan 125 Tablet, consult a doctor if you are considering fathering a child, as it may reduce sperm count. For pediatric use, this medication is suitable for children and adolescents over one year old to treat pulmonary hypertension only. It is not suggested for treating systemic sclerosis or ongoing digital ulcer disease in children. Prior to giving this medicine to a child, seek advice from a healthcare professional.


Side effects of Bosentan 125 Tablet

Bosentan 125 Tablet may cause some side effects, although most of them are not worrisome and typically go away as your body gets used to the medication. However, if any side effects persist or you are concerned about them, it is essential to consult your doctor promptly. Common side effects that can occur with Bosentan 125 Tablet include headache, ankle swelling, edema (swelling), diarrhea, anemia (low red blood cell count), and respiratory tract infections. Other side effects that may occur but are less common include oedema (swelling of legs and ankles), flushed appearance or redness of the skin, signs of hypersensitivity reactions like skin inflammation, itching, and rashes, gastroesophageal reflux disease (acid reflux), syncope (fainting), palpitations (fast or irregular heartbeats), low blood pressure, nasal congestion, and signs of anaphylactic reaction such as skin rash, nausea, difficulty in breathing, and shock. In rare cases, Bosentan 125 Tablet may lead to serious side effects like abnormal liver function, vomiting, dark urine, cirrhosis or scarring of the liver, and liver failure. If you experience any signs of impaired liver function such as nausea, fever, stomach pain, jaundice (yellowing of skin or eyes), dark urine, itching, fatigue, or flu-like symptoms including joint and muscle pain with fever, stop taking the medication immediately and seek medical attention.


Safety advice

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liver

When taking Bosentan 125 Tablet, it is important to be cautious if you have liver disease. Your doctor may need to adjust the dose to ensure it is safe for you. It is not advisable to use Bosentan 125 Tablet if you have moderate or severe liver disease. Remember to consult your doctor before starting or continuing this medication, especially if you have any liver issues.

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kidney

Bosentan 125 Tablet is safe for patients with kidney disease, and no dosage adjustment is necessary.

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alcohol

When taking Bosentan 125 Tablet, be aware that it can lead to increased drowsiness in combination with alcohol.

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driving

When taking Bosentan 125 Tablet, be cautious while driving as it may lower your blood pressure, causing dizziness that can impact your driving ability.

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pregnancy

Bosentan 125 Tablet is not safe to use during pregnancy. Pregnant women should consult their doctor due to potential harm shown in studies on both pregnant women and animals.

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breastfeeding

Caution is advised while breastfeeding as Bosentan 125 Tablet may be unsafe, with potential to pass into breastmilk and harm the baby.


Age above 75(Geriatrics)

BOSENTAS 125MG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking the medicine.

Consumption warning before consuming Bosentan 125 Tablet

Before consuming Bosentan 125 Tablet 10's, it is crucial to be aware of certain warnings. Firstly, if you have an allergy to Bosentan 125 Tablet 10's or any of its components, do not take this medication. Inform your doctor if you have liver problems before starting Bosentan 125 Tablet 10's, as it can impact liver function. Pregnant or breastfeeding women should avoid Bosentan 125 Tablet 10's, classified as a pregnancy category X drug that may cause birth defects. If you plan to conceive after discontinuing the medication, wait at least a month to ensure complete elimination from the body. It is advised that women taking Bosentan 125 Tablet 10's use a reliable contraceptive method and continue contraception for a month post-treatment. Regular monitoring of liver function and hemoglobin levels is essential, as low hemoglobin could indicate anemia.


What if you forgot to take Bosentan 125 Tablet?

If you forget to take a dose of Bosentan 125 Tablet, try to take it as soon as you remember. But, if it's nearly time for your next dose, then just skip the missed one and resume your normal dosing schedule. Avoid taking a double dose to make up for the missed one. It's important to stay consistent with your dosing routine for the medication to work effectively.


What happens if you take overdose of Bosentan 125 Tablet?

If an individual accidentally consumes an excessive amount of Bosentas 125mg Tablet, it is essential to seek prompt medical attention. In case of an overdose, contact your doctor immediately or go to the nearest hospital for proper management of the symptoms. It is crucial to act swiftly to address the potential effects of taking too much of this medication.


Related lab tests

Related Lab Tests for monitoring patients on Bosentan 125 Tablet include an Echocardiogram and Right heart catheterization. An Echocardiogram is a non-invasive test that uses sound waves to create images of the heart. It helps in evaluating the structure and function of the heart, including the heart valves and chambers. This test can give insights into the impact of Bosentan 125 Tablet on the heart's health and function.

On the other hand, Right heart catheterization is an invasive procedure that involves inserting a catheter into the heart to measure pressures within the heart and lungs. This test provides information on the blood flow and oxygen levels in the heart and lungs. It is used to assess the impact of pulmonary hypertension, which Bosentan 125 Tablet is commonly prescribed for.

Both these lab tests are essential for monitoring patients on Bosentan 125 Tablet to ensure the drug's effectiveness and to detect any potential adverse effects on the heart and pulmonary system. Regular monitoring through these tests can help healthcare providers make informed decisions about the patient's treatment plan and overall health management.


Additional Information

Habit FormingNo
Chemical ClassSulfonamide and Pyrimidine Derivative
Therapeutic Class-
Action ClassEndothelin receptor blocker

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

1590

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024