Bioval 500 CR Tablet
By Bioval
Rx
10 Tablet CR in a Strip

Composition
Sodium Valproate(375mg) + Valproic Acid(87mg)

Manufacturer - Biochem Pharmaceutical Industries
BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.

Expires on or after
August, 2026
About Bioval 500 CR Tablet
Bioval 500 CR Tablet is a combination of two medicines used to treat epilepsy, a neurological disorder that causes recurrent seizures or fits. It works by controlling abnormal brain activity, relaxing nerves, and preventing seizures. It is important to take Bioval 500 CR Tablet with food as prescribed by your doctor, and the dosage may be gradually increased until your condition stabilizes. It may take several weeks for this medicine to show its full effect, so it's crucial to take it regularly without stopping abruptly.
There are common side effects associated with Bioval 500 CR Tablet, such as nausea, vomiting, loss of appetite, headache, sleepiness, tremors, hair loss, and liver injury. While most side effects tend to diminish over time, it's important to inform your doctor if they persist or bother you. Prior to taking this medicine, discuss with your doctor if you have kidney or liver issues, meningitis, depression, or if you are on other medications that may interact with Bioval 500 CR Tablet.
It is advised to refrain from consuming alcohol while on Bioval 500 CR Tablet as it may exacerbate certain side effects. Additionally, the drug may lead to weight gain, so maintaining a healthy diet and regular exercise routine is recommended. You should also be vigilant for any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medication.
Bioval 500 CR Tablet contains Sodium Valproate, categorized as a Mood stabilizer. It is primarily used to manage mania associated with bipolar disorder when lithium is not suitable. Moreover, Bioval 500 CR Tablet is also prescribed for treating complex partial seizures, simple and complex absence seizures, and preventing migraine headaches. It is essential to inform your doctor about any pre-existing medical conditions or genetic diseases before starting this medication.
Patients taking Bioval 500 CR Tablet should be monitored for signs of suicidal ideation and behavior, and immediate medical advice should be sought if any concerning signs manifest. Pregnant or breastfeeding women, as well as children under 2 years of age, are not recommended to use Bioval 500 CR Tablet due to the increased risk of liver toxicity. If you experience any worsening symptoms while on this medication, consult your healthcare provider promptly.
Benefits
Bioval 500 CR Tablet offers several benefits for individuals dealing with epilepsy. The tablet works by slowing down the electrical signals in the brain that cause seizures. By doing so, it can effectively reduce various symptoms associated with epilepsy, including confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medication can provide a sense of relief and empowerment as it enables individuals to engage in activities they may have previously avoided due to fear, such as swimming and driving. It is important to note that while Bioval 500 CR Tablet may take a few weeks to show its full effectiveness, as the dose needs to be increased gradually, it is crucial to continue taking the medication as prescribed by the doctor, even if the individual starts to feel better. Abruptly stopping the medication can potentially lead to increased seizure activity. Consistent and proper use of this medication is key in managing epilepsy effectively and minimizing the risk of seizures.
How to use the Bioval 500 CR Tablet
To use Bioval 500 CR Tablet, follow the instructions provided by your doctor meticulously. Take the tablet as a whole with a glass of water. It is important not to crush, chew, or break the tablet. Remember to consume Bioval 500 CR Tablet alongside food. Your physician will determine the appropriate dosage and duration based on factors such as your age, weight, and the type of illness you are dealing with. It is crucial to continue taking Bioval 500 CR Tablet as directed by your doctor; do not discontinue unless specifically advised to do so by your doctor.
Uses of Bioval 500 CR Tablet
Bioval 500 CR Tablet is commonly used to manage epilepsy, especially in treating complex partial seizures in adults and children aged 10 and above. It is also effective in addressing simple and complex absence seizures, either alone or in combination with other seizure types. Additionally, this medication is useful in the management or control of mania associated with bipolar disorder. Another important use of Bioval 500 CR Tablet is to help prevent migraine headaches.
What conditions Bioval 500 CR Tablet treats?
Bioval 500 CR Tablet is used to treat epilepsy, a neurological disorder characterized by recurring seizures. It works by controlling abnormal brain activity, calming nerves, and preventing seizures. The medication may take time to show effects and should be taken regularly as prescribed by your doctor. Common side effects include nausea, vomiting, headaches, and liver injury. Inform your doctor if you have kidney or liver issues, depression, or take other medications. You should avoid alcohol while on this medication and let your doctor know about any mood changes or suicidal thoughts.
Should you consult a doctor?
It is important to seek a doctor's advice before taking Bioval 500 CR Tablet if you are switching from another medicine containing valproate, have a history of fits or brain-related conditions, pancreas issues, high blood sugar, or are being tested for diabetes. Additionally, if you are carnitine palmitoyl transferase type II deficient, have systemic lupus erythematosus, depression, mood disorders, suicidal thoughts or behavior, or any other medical conditions, consult a healthcare professional before using this medication.
Do not use Bioval 500 CR Tablet if you have porphyria, urea cycle disorder, or a genetic problem related to a mitochondrial disorder, such as Alpers-Huttenlocher syndrome. Seeking medical advice is crucial to ensure the safe and appropriate use of this medication based on your individual health profile and medical history.
Side effects of Bioval 500 CR Tablet
Bioval 500 CR Tablet may cause several side effects that may not necessarily need medical attention as your body adjusts to the medication. Common side effects include nausea, vomiting, weight gain, loss of appetite, gum swelling, headache, sleepiness, tremors, hair loss, liver injury, increased liver enzymes, bleeding gums, epigastralgia, diarrhea, memory impairment, decreased sodium level in blood, anemia, and pain during periods.
Additionally, more serious side effects may require immediate medical attention. These can include toxic epidermal necrolysis or Stevens-Johnson Syndrome characterized by blistering, peeling, or bleeding of the lips, eyes, mouth, nose, genitals, hands, or feet, with or without rash, fever, chills, or muscle aches. Other severe reactions may include erythema multiforme, angioedema, or anaphylactic reactions, and Drug Rash with Eosinophilia and Systemic Symptoms (DRESS).
Liver problems can manifest as sudden illness with symptoms such as nausea, vomiting, extreme tiredness, weakness, stomach pain, yellow skin or eyes, loss of appetite, swollen legs and feet, recurring fits, dark urine, and swollen face. Pancreatic problems may display as severe stomach pain, nausea, or vomiting that persists. Decreased platelet count, severe decrease of white blood cells, low red blood cell count, pancytopenia, jerky muscle movements, among others, may also occur.
Some rare side effects to watch out for are systemic lupus erythematosus (SLE), kidney problems like renal failure, and Syndrome of Inappropriate Antidiuretic Hormone (SIADH) secretion causing confusion. Suicidal thoughts or actions, very low body temperature, and drowsiness especially in the elderly are also possible side effects of Bioval 500 CR Tablet. If you experience any of these severe reactions, it is important to stop taking the medication immediately and contact your doctor for further evaluation and guidance.
Safety advice

liver
Caution should be taken when using Bioval 500 CR Tablet in patients with liver disease. It may be necessary to adjust the dose of the tablet. It is important to consult your doctor before using Bioval 500 CR Tablet. The tablet is not recommended for patients with severe or active liver disease.

kidney
Bioval 500 CR Tablet is considered safe for use in patients with kidney disease. Limited data indicates that dose adjustment may not be necessary. It's recommended to consult a doctor if you have an underlying kidney condition.

alcohol
It is not safe to drink alcohol while taking Bioval 500 CR Tablet.

driving
When using Bioval 500 CR Tablet, be cautious of decreased alertness, impaired vision, drowsiness, or dizziness. Refrain from driving if experiencing these effects.

pregnancy
Bioval 500 CR Tablet is unsafe during pregnancy with evidence of risk to the baby. Rarely prescribed in life-threatening cases if benefits outweigh risks. Consult your doctor for guidance.

breastfeeding
Bioval 500 CR Tablet is considered safe to use while breastfeeding. Research indicates the medication does not transfer into breastmilk in concerning quantities, posing no risk to the infant.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Bioval 500 CR Tablet
Before consuming Bioval 500 CR Tablet, it is important to consider several factors. This medication is used to treat epilepsy, a condition characterized by recurrent seizures or fits. It works by controlling abnormal brain activity and relaxing nerves to prevent seizures. Always take Bioval 500 CR Tablet with food as directed by your doctor. The dosage will be determined by your doctor and may be gradually increased until your condition stabilizes. It may take some weeks for the medicine to show its full effect, so it is crucial to take it regularly as prescribed.
Possible side effects of Bioval 500 CR Tablet include nausea, vomiting, loss of appetite, and headache. These side effects are usually temporary but if they persist, inform your doctor. Prior to taking this medication, inform your doctor of any kidney or liver issues, meningitis, depression, or suicidal thoughts. It is essential to disclose all other medications you are taking to prevent interactions. Pregnant or breastfeeding individuals should consult their doctor before taking this medication, as adjustments may be necessary. Avoid alcohol while on this medication, as it may worsen side effects. Regular blood tests may be required to monitor your response. If you experience unusual changes in mood or behavior, contact your doctor immediately.
What if you forgot to take Bioval 500 CR Tablet?
If you forget to take a dose of Bioval 500 CR Tablet, try to take it as soon as you remember. But if it's almost time for your next scheduled dose, it's best to skip the missed dose and stick to your regular dosing schedule. Avoid taking a double dose to make up for the missed one, as this can be harmful. Remember, consistency in taking your medication as prescribed is key to ensuring its effectiveness.
What happens if you take overdose of Bioval 500 CR Tablet?
In case of accidentally taking an excessive amount of Bioval 500 CR Tablet, it is crucial to seek immediate medical assistance. Symptoms of an overdose may include nausea, vomiting, headache, blurred eyesight, dizziness, poor reflexes, confusion, memory loss, tiredness, weak or 'floppy' muscles, fits, loss of consciousness, behavioral changes, fast breathing, shortness of breath, or chest pain. It is advisable to consult a doctor without delay or proceed to the nearest hospital if an overdose is suspected.
Related lab tests
For patients taking Bioval 500 CR Tablet, there are a few related lab tests that may be necessary to monitor their health and ensure the medication is working effectively. These lab tests include an Electroencephalogram (EEG) and MRI. An EEG is a test that measures the electrical activity in the brain, which can help detect any abnormalities or changes in brain function. This test may be recommended for patients taking Bioval 500 CR Tablet to assess the impact of the medication on brain activity. Additionally, an MRI, which stands for Magnetic Resonance Imaging, is a test that uses powerful magnets and radio waves to create detailed images of the brain and other parts of the body. This test can provide valuable information about brain structure and any potential changes that may be relevant for patients on Bioval 500 CR Tablet. Both of these lab tests can play a critical role in monitoring the health and treatment progress of individuals using Bioval 500 CR Tablet.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | NEURO CNS |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Monie Riju Simon
MBBS - General Medicine
Last update on 11-Feb-2025