Biduret Tablet

By Biduret

Rx

10 Tablet in a Strip

Composition icon

Composition

Amiloride(5mg) + Hydrochlorothiazide(50mg)

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd icon

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd

Dr. Annie Besant Road, Mumbai - 400 030

Expires on or after icon

Expires on or after

May, 2026

About Biduret Tablet

Biduret Tablet is a medication that combines two medicines to help address hypertension, commonly known as high blood pressure. This condition occurs when the force of blood against the walls of blood vessels is too high, potentially leading to serious health issues such as heart attack, stroke, heart failure, and kidney problems. Biduret Tablet is also used to treat oedema, which is characterized by fluid retention and swelling in the ankles, feet, and legs.

The key components of Biduret Tablet are Amiloride and Hydrochlorothiazide. These act as diuretics, commonly referred to as water pills, by aiding in the removal of excess fluids and electrolytes from the body through urine. Amiloride works by blocking sodium-potassium exchange in the distal tubule of the kidney, assisting in the elimination of extra fluids that, if left untreated, can strain the heart, blood vessels, lungs, kidneys, or liver. On the other hand, Hydrochlorothiazide increases urine production, effectively reducing fluid overload and treating swelling associated with heart, liver, kidney, or lung conditions.

To ensure the effectiveness of Biduret Tablet, it is recommended to take the medication as prescribed by your healthcare provider. Taking the tablet at the same time each day can aid in achieving optimal results. Common side effects of Biduret Tablet may include nausea, vomiting, diarrhea, headache, weakness, electrolyte imbalance, and increased uric acid levels in the blood. Most of these side effects are temporary and self-resolving, but it is advisable to consult your doctor if they persist.

Prior to initiating Biduret Tablet, inform your doctor about any allergies to the medication or its components. It is crucial not to discontinue the medication without medical guidance. Biduret Tablet is not suitable for individuals with conditions such as diabetes, high blood potassium levels, kidney or liver disorders, and should not be taken by pregnant or breastfeeding individuals. It is also not recommended for use in children under 18 years of age. Additionally, driving after taking Biduret Tablet is discouraged due to potential drowsiness and dizziness that may occur as side effects.


Benefits

Biduret Tablet provides several benefits for individuals dealing with hypertension, heart failure, and fluid retention issues. This medication helps by relaxing the blood vessels, allowing for smoother blood flow throughout the body. By eliminating excess water and increasing urine output, Biduret Tablet aids in maintaining a balance of electrolytes, particularly potassium, which is crucial for overall health. These actions collectively contribute to lowering blood pressure levels and reducing the likelihood of future cardiovascular and kidney problems, such as strokes, heart attacks, and kidney issues.

The combination of amiloride and hydrochlorothiazide in Biduret Tablet serves specific purposes in treating different conditions. Amiloride, classified as a 'potassium-sparing diuretic,' is effective in addressing hypokalemia, a condition characterized by low potassium levels in individuals with high blood pressure or heart failure. On the other hand, hydrochlorothiazide works by blocking sodium reabsorption in the kidneys, leading to increased excretion of sodium, potassium, water, and hydrogen ions. This dual-action mechanism of Biduret Tablet makes it beneficial for managing high blood pressure, fluid retention in heart failure patients, liver cirrhosis, kidney disorders, and oedema induced by steroid or estrogen therapy.

Biduret Tablet operates on various kidney functions, facilitating the removal of excess fluids and electrolytes while ensuring a proper potassium balance in the body. By promoting the excretion of surplus fluids in the form of urine, Biduret Tablet plays a critical role in regulating blood pressure and alleviating symptoms associated with fluid retention conditions. It is important to take this medication regularly as prescribed to experience its full effectiveness, even if there is no immediate noticeable improvement, as Biduret Tablet works to maintain your well-being over the long term.


How to use the Biduret Tablet

To properly use Biduret Tablet, it is important to follow the advice of your doctor regarding the correct dose and duration of treatment. Take Biduret Tablet with food to ensure optimal absorption by the body. Swallow the tablet whole with a glass of water, without chewing, crushing, or breaking it. Your doctor will determine the duration of treatment based on your specific medical condition. It is essential to adhere to the prescribed guidelines to experience the full benefits of Biduret Tablet and to prevent any potential side effects. If you have any questions or concerns about using Biduret Tablet, be sure to consult your doctor for further clarification.


Uses of Biduret Tablet

Biduret Tablet is primarily used to treat hypertension, which is also known as high blood pressure. This medication is also beneficial in managing heart failure and Oedema, which is the medical term for fluid retention. By effectively controlling blood pressure levels, Biduret Tablet helps in reducing the risk of heart disease and other associated complications. Additionally, it plays a key role in improving heart function and reducing swelling due to fluid buildup in the body.


What conditions Biduret Tablet treats?

Hypertension, a chronic condition characterized by high blood pressure, can lead to severe heart diseases like stroke and heart attack if left uncontrolled. This happens when the heart pumps more blood, causing arteries to narrow and blood pressure to rise. Uncontrolled high blood pressure can also result in brain damage (stroke) and kidney failure. Symptoms of hypertension include headache, nosebleed, vomiting, and chest pain. Ideal blood pressure ranges from 90/60mmHg to 120/80mmHg, and hypertension is diagnosed with systolic pressure over 140mmHg and diastolic pressure above 90mmHg.


Should you consult a doctor?

If you experience persistent side effects such as nausea, vomiting, diarrhea, or dehydration while taking Biduret Tablet, it is important to consult your doctor. These side effects can be common and usually subside as your body gets used to the medicine, but if they persist or if you are concerned about them, seeking medical advice is recommended. Additionally, if you encounter symptoms like headache, dizziness, rash, or decreased appetite that are bothersome or persistent, it is advisable to consult your healthcare provider. Furthermore, if you have any concerns about the impact of the medication on your kidney function, or if you have a history of liver or kidney disease, it is crucial to communicate this with your doctor before using Biduret Tablet. Always keep your healthcare team informed about any other medications you are taking, as they may interact with or be affected by Biduret Tablet. It is essential to follow your doctor's advice on the dosage and duration of treatment with this medication.


Side effects of Biduret Tablet

When taking Biduret Tablet, some common side effects may occur, but most of these should not need medical attention and usually go away as your body gets used to the medicine. However, it is important to consult your doctor if the side effects persist or if you are concerned about them. Possible side effects of Biduret Tablet include headaches, dizziness, rashes, decreased appetite, nausea, vomiting, diarrhea, glucose intolerance, weakness, muscle cramps, and electrolyte imbalances. Additionally, Biduret Tablet may lead to an increased level of uric acid in the blood. If you experience any of these side effects, speak to your healthcare provider for proper guidance.


Safety advice

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liver

When considering using Biduret Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require dose adjustments for Biduret Tablet. It is advisable to consult your doctor regarding the use of this medication in such cases.

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kidney

Biduret Tablet should be used carefully in patients with kidney disease. Consult your doctor for potential dose adjustments. Avoid using Biduret Tablet in cases of severe kidney disease.

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alcohol

Consuming alcohol with Biduret Tablet is not safe.

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driving

Biduret Tablet can reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these side effects.

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pregnancy

Biduret Tablet is typically safe to use during pregnancy. Animal studies suggest minimal adverse effects on the baby, but human studies are limited. It's advisable to consult a healthcare provider for personalized guidance.

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breastfeeding

Biduret Tablet is considered safe for breastfeeding. Current data indicates no significant risk to the baby.


Consumption warning before consuming Biduret Tablet

Before consuming Biduret Tablet 10's, it is crucial to note a few important warnings. Avoid using this medication if you have allergies to Biduret Tablet 10's or any of its ingredients. Inform your doctor about any prescription or non-prescription medications you are currently taking. Make sure to disclose any existing untreated salt/mineral imbalances, kidney disease, liver disease, or diabetes to your doctor before starting Biduret Tablet 10's. Notify your doctor if you have Addison's disease, gout, vision problems, or eye pain. Refrain from taking Biduret Tablet 10's if you have specific conditions such as high cholesterol, abnormal heartbeat, or heart failure. In case of diarrhoea or severe vomiting, seek medical advice promptly. Prior to using Biduret Tablet 10's, tell your doctor if you have had skin cancer. It is crucial to inform your doctor if you are pregnant or breastfeeding, as Biduret Tablet 10's is not suitable for use in these situations. Additionally, this medication is not recommended for individuals under 18 years of age. Be cautious while driving after taking Biduret Tablet 10's, as it may lead to drowsiness and dizziness.


Disease interactions

When taking Biduret Tablet 10's, it is crucial to inform your doctor if you have any existing conditions such as salt/mineral imbalance (specifically high potassium or low sodium levels), kidney disease, liver disease, or gout. These conditions may interact with the medication and could potentially lead to adverse effects or complications. By disclosing this information to your doctor, they can assess whether Biduret Tablet is safe for you to use and may need to adjust the dosage or consider alternative treatment options to ensure your safety and well-being.


What if you forgot to take Biduret Tablet?

If you forget to take a dose of Biduret Tablet, try to take it as soon as you remember. But if it is almost time for your next scheduled dose, it is better to skip the missed dose and resume your normal dosing schedule. Never take an extra dose to make up for the missed one, as this could lead to potential health risks. It is important to follow your prescribed dosing regimen closely for the best results from your medication.


Related lab tests

When taking Biduret Tablet, it is important to monitor your kidney function regularly through various lab tests. Some related lab tests that your doctor may recommend include:

1. Serum Creatinine Test: This test measures the level of creatinine in your blood, which helps assess how well your kidneys are functioning. An increase in creatinine levels may indicate kidney damage.

2. Blood Urea Nitrogen (BUN) Test: The BUN test measures the amount of nitrogen in your blood that comes from urea, a waste product of protein metabolism. Elevated BUN levels can be a sign of kidney problems.

3. Urinalysis: This test involves analyzing a sample of your urine for abnormalities such as blood, protein, or infection. It can provide valuable information about your kidney health.

4. Glomerular Filtration Rate (GFR) Test: The GFR test estimates how much blood passes through the glomeruli in your kidneys each minute. It is a more accurate measure of kidney function than creatinine levels alone.

5. Electrolyte Panel: This test measures the levels of electrolytes such as sodium, potassium, and chloride in your blood, which can be affected by kidney function.

It is important to follow your healthcare provider's recommendations for these lab tests to ensure your kidneys are functioning properly while taking Biduret Tablet.


Additional Information

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025