Azactiv 100mg Injection

By Azactiv

Rx

1 Injection in a Vial

Composition icon

Composition

Azacitidine(100mg)

Manufacturer - Glenmark Pharmaceuticals Ltd icon

Manufacturer - Glenmark Pharmaceuticals Ltd

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Expires on or after icon

Expires on or after

August, 2025

About Azactiv 100mg Injection

Azactiv 100mg Injection is a medication used in the treatment of certain types of blood cancer, specifically Myelodysplastic Syndrome (MDS) in adult patients. It may also be prescribed for other conditions based on the doctor's recommendation. The injection is administered under the supervision of a medical professional, who will determine the appropriate dosage and frequency of administration tailored to the patient's specific condition. It is crucial to follow the doctor's instructions carefully to avoid any potential serious side effects.

The effects of Azactiv 100mg Injection may not be immediate, and it could take several weeks or months before the benefits become noticeable. Patients are advised not to discontinue the medication without consulting their doctor, even if the desired effects are not immediately apparent. Common side effects of this medication include reactions at the injection site such as pain, swelling, and redness, as well as symptoms like vomiting, weakness, and nausea. If these side effects are severe or persistent, it is important to inform the doctor for suitable management options.

Patients undergoing treatment with Azactiv 100mg Injection should be aware of the necessity for regular blood tests to monitor their blood cell count, as well as assess the functioning of the heart, liver, and kidneys. It is crucial to keep the doctor informed about any other medications being used, as Azactiv 100mg Injection may interact with other drugs, affecting their efficacy or causing adverse reactions. Prior to starting the medication, patients should disclose any existing liver or kidney issues, as well as inform the doctor if they are taking medicines for infections.

It is important to note that Azactiv 100mg Injection is not recommended for use during pregnancy or while breastfeeding due to potential risks to the unborn child or nursing infant. Patients should discuss any concerns or questions about the medication with their healthcare provider before initiating treatment.


Benefits

Azactiv 100mg Injection is a powerful medication used in the treatment of blood cancer, also known as leukemia. This type of cancer affects the blood-forming tissues and weakens the body's immune system. Azactiv 100mg Injection works by targeting and eliminating cancer cells, as well as preventing their further growth and multiplication. It is essential to have a thorough discussion with your healthcare provider about the potential risks and benefits of Azactiv 100mg Injection before starting the treatment.


Moreover, Azactiv 100mg Injection is also utilized in the management of myelodysplastic syndrome, a group of conditions where the bone marrow generates abnormal blood cells that are deficient in both structure and function. By effectively killing or impeding the growth of cancer cells and inhibiting their multiplication, Azactiv 100mg Injection plays a crucial role in combating this condition. As with any potent medication, it is important to be aware of the potential risks and benefits associated with Azactiv 100mg Injection, and this should be discussed with your doctor prior to starting the treatment.


It is noteworthy that while undergoing treatment with Azactiv 100mg Injection, it is advisable to avoid alcohol consumption and ensure adequate hydration by drinking plenty of water. These measures can help optimize the effectiveness of the treatment and minimize potential side effects. Overall, Azactiv 100mg Injection offers significant benefits in the treatment of blood cancer and myelodysplastic syndrome by targeting and halting the growth of cancer cells, and consulting with your healthcare provider is crucial in maximizing the benefits of this potent medication.


How to use the Azactiv 100mg Injection

When you receive Azactiv 100mg Injection, a doctor or nurse will administer it to you. Do not try to give yourself this medicine; it must be given by a healthcare professional. The injection will be given underneath the skin, in areas such as your thighs, arms, or abdomen. Your doctor will determine the right amount of the medication and how long you should receive it based on factors such as your age, weight, and the specific condition being treated. Trust your healthcare provider to handle the administration of Azactiv 100mg Injection to ensure it is done safely and effectively for your well-being.


Uses of Azactiv 100mg Injection

Azactiv 100mg Injection is commonly used in the treatment of various sub-types of myelodysplastic syndromes (MDS), a group of cancers linked to the blood and bone marrow. It is also effective in treating Chronic myelomonocytic leukaemia (CMML), which is a type of blood cancer affecting monocytes, and acute myeloid leukaemia (AML), a blood cancer of white blood cells. This injection plays a crucial role in managing these conditions and providing relief to patients.


What conditions Azactiv 100mg Injection treats?

Azactiv 100mg Injection is used to treat blood cancer, also known as leukemia. It is particularly used for Myelodysplastic Syndrome (MDS) in adults. This medicine works by killing cancer cells and preventing their growth. It is vital to follow your doctor's instructions for dosage and timing to avoid serious side effects. Common side effects include injection site reactions, vomiting, weakness, and nausea. Regular blood tests are necessary during treatment to monitor your blood cells, heart, liver, and kidney function. Azactiv 100mg Injection is not recommended during pregnancy or breastfeeding.


Should you consult a doctor?

Before receiving Azactiv 100mg Injection, it is important to inform your doctor if you have low red blood cell (RBC), white blood cell (WBC), or platelet count in your blood. If you experience any symptoms such as unexplained fatigue, easy bruising, frequent infections, or unusual bleeding, it is crucial to seek medical attention promptly. These could be indicative of complications related to your blood cell counts and may require immediate intervention from a healthcare provider. Prioritize regular monitoring of your blood counts and report any concerning symptoms to your doctor for further evaluation.


Side effects of Azactiv 100mg Injection

Azactiv 100mg Injection may cause various side effects, though most do not require medical attention and tend to resolve as your body gets used to the medication. Injection site reactions like pain, swelling, and redness are common. Other common side effects include vomiting, weakness, nausea, decreased potassium levels in the blood, bruises, fever, chills, diarrhea, and constipation. Some individuals may experience more serious side effects, such as painful skin ulceration, low red blood cell count leading to anemia, increased risk of infections like pneumonia, fever, and chills, and a higher tendency to bleed due to low blood platelet counts. Additional side effects may include gastrointestinal issues like stomach pain, loss of appetite, and constipation, as well as fatigue, weakness, joint pain, muscle pain, and skin rashes with redness and itching. You may also experience headaches, dizziness, insomnia, nosebleeds, gum bleeding, weight loss, urinary tract infections, mouth ulcers, high or low blood pressure, anxiety, hair loss, and dehydration. Contact your doctor immediately if you notice any signs of liver or kidney problems, increased infections, lung infections, abnormal bleeding, allergic reactions, or signs of blood infections. Your doctor can provide guidance and support to manage any side effects effectively.


Safety advice

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liver

When using Azactiv 100mg Injection, it is important to be cautious if you have liver disease. In such cases, a dose adjustment of the injection may be necessary. It is strongly advised to consult your doctor before using Azactiv 100mg Injection if you have any liver-related issues. Please note that the use of Azactiv 100mg Injection is not recommended for patients with advanced liver cancer.

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kidney

Azactiv 100mg Injection requires caution in patients with kidney disease. Adjustments in dosage may be necessary. Consult your doctor for guidance.

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alcohol

It is not confirmed if alcohol can be safely consumed with Azactiv 100mg Injection. It is advisable to seek advice from your doctor before combining alcohol with this medication.

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driving

When using Azactiv 100mg Injection, be cautious while driving as it may cause tiredness and affect your ability to drive. Be aware of potential side effects that could impair your focus and reaction time while driving.

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pregnancy

Azactiv 100mg Injection is not safe during pregnancy due to potential risk to the baby. Nonetheless, in rare life-threatening cases, a doctor may prescribe it if benefits outweigh risks. Consult your doctor before use.

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breastfeeding

Azactiv 100mg Injection is not recommended for use while breastfeeding as it may be harmful to the baby, potentially causing toxicity.


Age above 75(Geriatrics)

Azactiv 100mg Injection is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor for advice.


Age below 6 months(Pediatrics)

Azactiv 100mg Injection should be used with caution in patients with a previous history of heart attack or any other heart conditions. Therefore, inform your doctor before receiving it.


Consumption warning before consuming Azactiv 100mg Injection

Before using Azactiv 100mg Injection, it is important to understand that this medication is primarily used to treat certain types of blood cancer, specifically Myelodysplastic Syndrome (MDS) in adult patients. The injection should only be administered under the supervision of a healthcare professional, who will determine the appropriate dosage and frequency based on your condition. It is crucial to follow your doctor’s instructions precisely to avoid serious side effects that can result from incorrect use or overdosing.


Common side effects of Azactiv 100mg Injection may include reactions at the injection site, vomiting, weakness, and nausea. If these side effects become bothersome or severe, it is essential to notify your doctor. Additionally, before undergoing any vaccinations while on this treatment, consult your doctor. Regular blood tests will be necessary to monitor your blood cells, heart, liver, and kidneys during the course of treatment.


Prior to starting Azactiv 100mg Injection, inform your doctor about any existing liver or kidney issues, as well as any medications you are currently taking. This medication should be avoided during pregnancy or while breastfeeding. It is crucial to be fully transparent with your healthcare provider about your medical history and current medications to ensure the safe and effective use of Azactiv 100mg Injection.


What happens if you take overdose of Azactiv 100mg Injection?

If too much Azactiv 100mg Injection, specifically the 100mg dose, is accidentally taken, it is crucial to seek immediate medical attention. Consulting a doctor or going to the nearest hospital without delay is vital in case of an overdose of Azactiv 100mg Injection.


Related lab tests

In the context of Azactiv 100mg Injection, several related lab tests can help assess the effectiveness and potential side effects of the treatment. One important test is the Bone Marrow Smear Microscopy Examination. This test involves examining the bone marrow sample under a microscope to evaluate the cells for abnormalities or changes caused by the treatment. Another crucial test is the Complete Blood Count, which provides information on the levels of different blood components such as red blood cells, white blood cells, and platelets. Changes in these levels can indicate the impact of Azactiv 100mg Injection on the body. Additionally, the Peripheral Smear Examination is another valuable test that involves looking at a sample of blood under a microscope to assess the shape and size of blood cells. This test can help detect any irregularities in blood cell morphology that may be associated with the medication. Regular monitoring of these lab tests can provide valuable insights into the patient's response to Azactiv 100mg Injection treatment.


Additional Information

Habit FormingNo
Chemical ClassPyrimidine Nucleoside Analogue
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolites

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024