Avastimab 400mg Injection

By Avastimab

Rx

16ml Injection in a Vial

Composition icon

Composition

Bevacizumab(400mg)

Manufacturer - RPG Life Sciences Ltd icon

Manufacturer - RPG Life Sciences Ltd

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Expires on or after icon

Expires on or after

September, 2025

About Avastimab 400mg Injection

Avastimab 400mg Injection is a potent anticancer medication widely used in the treatment of various types of cancers, specifically colon and rectal cancer, non-small cell lung cancer, kidney cancer, brain tumor, ovarian cancer, and cervical cancer. This medication works by inhibiting the growth of new blood vessels that supply tumors, thereby halting their growth. It is considered an effective first-line treatment option when administered in combination with other cancer medications.

When receiving Avastimab 400mg Injection, it is typically given as an infusion either through a small needle in a vein or through a port placed under the skin. The dosage and duration of treatment will be determined by the healthcare provider, who will also monitor for any signs of infusion reaction, such as elevated blood pressure or breathing difficulties. Treatment with Avastimab 400mg Injection is usually continued as long as the disease is under control and side effects remain manageable, with the doctor deciding if and when it should be discontinued.

Regular monitoring, including checking blood pressure and urine protein levels, may be advised while on this medication. It is essential to be aware of potential side effects, which can include rectal bleeding, taste changes, and headaches. Furthermore, caution should be exercised before undergoing any surgical procedures while on this medication, as it may impede wound healing and increase the risk of bleeding.

If you experience any unusual bleeding or bleeding tendencies, it is crucial to seek immediate medical advice. Additionally, it is important to inform your healthcare provider if you are pregnant, planning pregnancy, or breastfeeding, as Avastimab 400mg Injection may have implications in such situations. Due to potential interactions with other medications, it is vital to disclose all medicines you are currently taking to your healthcare team.


Benefits

Avastimab 400mg Injection offers a range of benefits in treating various types of cancers. In cases of colon and rectal cancer, it not only treats existing cancer but also reduces the risk of developing further cancerous growths. By killing or inhibiting the growth of cancer cells, Avastimab 400mg Injection effectively prevents the multiplication of these harmful cells in the colon or rectum. In non-small cell lung cancer, this medication is effective either alone or in combination with other treatments. It is crucial to discuss the potential risks and benefits with your doctor before starting treatment. Moreover, in kidney cancer, Avastimab 400mg Injection addresses symptoms such as blood in urine, weight loss, and fatigue while halting the advancement of cancer to other parts of the body. Similarly, for patients with brain tumors, ovarian cancer, and cervical cancer, this medication works by stopping the growth and multiplication of cancer cells, offering an effective treatment option. However, it is important to note that Avastimab 400mg Injection is a potent and toxic medicine, requiring careful adherence to doctor's instructions and a discussion of risks and benefits prior to use.


How to use the Avastimab 400mg Injection

To use Avastimab 400mg Injection, you should let your doctor or nurse administer the medicine to you. It comes in a 16 ml vial and must be given by a healthcare professional. It is important not to try to administer this injection on your own. This medication is meant to be administered by a trained professional to ensure proper dosage and safe administration. Be sure to follow your healthcare provider's instructions carefully and do not attempt to self-administer this injection. Your well-being is our top priority, and following these guidelines will help ensure the safe and effective use of Avastimab 400mg Injection.


Uses of Avastimab 400mg Injection

Avastimab 400mg Injection is used in the treatment of various types of cancers such as colon cancer, rectal cancer, non-small cell lung cancer, kidney cancer, brain tumor, ovarian cancer, and cervical cancer. It is particularly helpful in managing metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, as well as colorectal cancer. Avastimab 400mg Injection plays a crucial role in targeting these specific types of cancer and is considered as part of the treatment plan for patients diagnosed with these conditions.


What conditions Avastimab 400mg Injection treats?

Cancer is a disease where cells in a certain body area grow and replicate without control. These cancerous cells can invade and harm nearby healthy tissues and organs. Cancer usually starts in one spot and can spread to other parts of the body. Mutations in genes that control cell growth are what cause cancer to develop. These mutations make cells divide and multiply uncontrollably, leading to the formation of tumors. Treatment options for cancer often include surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy, and targeted drug therapy.


Should you consult a doctor?

If you experience rectal bleeding, changes in taste, headaches, nosebleeds, back pain, dry skin, high blood pressure, protein in urine, or nasal inflammation while taking Avastimab 400mg Injection, it is essential to consult your doctor. These symptoms may indicate potential side effects that require medical attention. Additionally, if you notice any unusual bleeding or have concerns about your condition, it is important to seek immediate medical advice. Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as Avastimab 400mg Injection may have implications for these scenarios. Moreover, if you are scheduled for surgery, it is crucial to disclose your medication to avoid complications with wound healing. Be vigilant about any changes in your health status and always communicate openly with your doctor about any concerns or new development while on Avastimab 400mg Injection.


Side effects of Avastimab 400mg Injection

When using Avastimab 400mg Injection, certain side effects may occur as your body gets used to the medication. Common side effects include rectal bleeding, taste changes, headaches, nosebleeds, back pain, dry skin, high blood pressure, presence of protein in urine, and nasal inflammation. Additionally, some users may experience constipation, loss of appetite, fever, nosebleeds, changes in speech, changes in taste perception, hoarseness in voice, and unexplained weight loss. Remember that most side effects are temporary and will fade over time, but if they persist or cause concern, do not hesitate to consult your healthcare provider.


Safety advice

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liver

Avastimab 400mg Injection appears to be safe for use in individuals with liver disease, as per the limited data available. It is suggested that adjusting the dosage of Avastimab 400mg Injection may not be necessary for patients with liver issues. It is advisable to consult your doctor before using this medication to ensure it is suitable for your specific condition.

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kidney

Avastimab 400mg Injection is likely safe for use in patients with kidney disease. Available data suggests no need for dose adjustment. Consult your doctor for guidance.

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alcohol

It is not certain if it is safe to drink alcohol while taking Avastimab 400mg Injection. Please consult your doctor.

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driving

Be cautious when driving after using Avastimab 400mg Injection due to reported side effects like sleepiness and fainting, which can affect your driving ability.

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pregnancy

Avastimab 400mg Injection may not be safe to use during pregnancy. Limited human studies and animal studies have shown negative effects on the developing baby. Your doctor will consider the benefits and risks before prescribing it to you. Please consult your doctor before using Avastimab 400mg Injection.

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breastfeeding

Avastimab 400mg Injection is likely unsafe during breastfeeding. Limited data indicates it may pass into breastmilk and harm the baby.


Consumption warning before consuming Avastimab 400mg Injection

Before consuming Bevarest-400 Injection 16 ml, it is crucial to seek medical supervision for your safety. Your doctor will closely monitor your condition during the treatment. Inform your doctor about any past allergic reactions to Avastimab 400mg Injection or other medications. If you are pregnant, it is advised to avoid taking Avastimab 400mg Injection and use effective contraception during the treatment and for 6 months after the last dose. Be aware that this injection may cause drowsiness and fainting, so refrain from driving while undergoing treatment. Notify your doctor if you have a history of high blood pressure, heart attack, stroke, bleeding disorders, or recent surgeries. Avoid breastfeeding during the treatment period and for 6 months after the final dose. Additionally, do not receive any vaccinations without your doctor's approval as Avastimab 400mg Injection may elevate the risk of bleeding. If you experience unusual bleeding or bruising, consult your doctor immediately.


Disease interactions

When using Avastimab 400mg Injection, it is crucial to inform your healthcare provider about any previous or current infections, bleeding disorders, fistula formation, GI perforation, hypertension, PRES (Posterior Reversible Encephalopathy Syndrome), proteinuria, and thromboembolic disorders. These conditions can potentially interact with the medication, affecting its effectiveness or causing adverse reactions. By disclosing this information to your doctor, they can make informed decisions about the appropriateness of Avastimab 400mg Injection for your specific health circumstances. It is important to prioritize your safety and well-being by ensuring open communication with your healthcare provider regarding any pre-existing medical conditions.


What if you forgot to take Avastimab 400mg Injection?

If you forget to take a dose of Avastimab 400mg Injection, it is important to speak with your doctor without delay. Consulting your doctor is essential to ensure you receive proper guidance on how to proceed after missing a dose of this medication. It is crucial not to take any extra doses to make up for the missed one without first consulting with your healthcare provider. Your doctor will be able to provide you with the necessary advice tailored to your specific situation.


Related lab tests

When considering 'Avastimab 400mg Injection', there are several related lab tests that may be important to consider. These include Carcino Embryonic Antigen, which is a blood test that can help in monitoring certain types of cancer. Another essential test is the Complete Blood Count (CBC), which provides information on different components of the blood like red blood cells and white blood cells. Human Papilloma Virus (HPV) testing can help in detecting the presence of this virus which is linked to certain types of cancers. Additionally, the Papanicolaou (PAP) Cytology test, commonly known as a Pap smear, is crucial for screening cervical cancer in women. These lab tests play a significant role in assessing health status and detecting potential issues that may require further evaluation or treatment.


Additional Information

Habit FormingNo
Chemical ClassMonoclonal Antibody
Therapeutic Class-
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024