Atrest 25 Tablet

By Atrest

Rx

10 Tablet in a Strip

Composition icon

Composition

Tetrabenazine(25mg)

Manufacturer - Centaur Pharmaceuticals Pvt Ltd icon

Manufacturer - Centaur Pharmaceuticals Pvt Ltd

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.

Expires on or after icon

Expires on or after

February, 2026

About Atrest 25 Tablet

Atrest 25 Tablet is a medication used to treat chorea, a movement disorder commonly associated with Huntington's disease. Chorea is characterized by involuntary, jerky movements that can significantly impact a person's quality of life. By balancing dopamine levels, Atrest 25 Tablet helps reduce these abnormal movements, allowing individuals to move and function better.

It is recommended to take Atrest 25 Tablet with or without food, preferably at the same time each day to maintain a consistent level of the medicine in the body. Following the dosage and duration prescribed by your doctor is crucial for optimal treatment outcomes. If a dose is missed, it should be taken as soon as remembered. However, abrupt discontinuation of the medication can worsen symptoms, so it is important to consult with a healthcare provider before making any changes. Immediate discontinuation is necessary if symptoms of neuroleptic malignant syndrome such as fever, muscle rigidity, altered consciousness, or seizures occur.

Common side effects of Atrest 25 Tablet may include nausea, insomnia, anxiety, fatigue, restlessness, depression, dizziness, and sleepiness. It is advised not to drive or engage in activities requiring mental focus until the effects of the medication are known. Any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts should be promptly reported to a healthcare professional.

Atrest 25 Tablet belongs to a class of medications called vesicular monoamine transporter 2 (VMAT2) inhibitors, specifically targeting the treatment of Huntington's disease. Huntington's disease is a genetic condition that leads to the degeneration of nerve cells in the brain. Atrest 25 Tablet contains tetrabenazine, which works by depleting certain chemical messengers in the brain involved in controlling body movements.

To effectively manage the condition, it is essential to adhere to the prescribed usage of Atrest 25 Tablet as directed by a healthcare provider. While experiencing common side effects like nausea, insomnia, anxiety, fatigue, sleepiness, restlessness, and depression, most of these symptoms tend to diminish over time without requiring medical intervention. However, frequent or severe side effects should be discussed with a doctor.

Before using ATREST 25MG TABLET, individuals with allergies to tetrabenazine or certain medical conditions such as Parkinson-like symptoms, depression, active suicidal thoughts, pheochromocytoma, kidney disorders, heart problems, liver problems, or intolerance to certain sugars should consult their doctor. Caution is advised when using the medication during pregnancy or for those planning pregnancy, as well as in elderly patients. ATREST 25MG TABLET is not recommended for children and adolescents below 18 years of age.

The most commonly reported side effects of ATREST 25MG TABLET include confusion, anxiety, insomnia, low blood pressure, gastrointestinal disturbances like nausea, vomiting, diarrhea, and constipation. If any of these symptoms worsen, it is important to seek medical advice promptly.


Benefits

Atrest 25 Tablet offers significant benefits in the treatment of chorea, a movement disorder commonly associated with Huntington's disease. Chorea is identified by uncontrollable jerky movements, which can greatly impact one's quality of life. Atrest 25 Tablet is specially formulated to address these symptoms and effectively manage the involuntary movements that characterize chorea. By taking Atrest 25 Tablet, individuals can experience an improvement in their daily functioning abilities, allowing them to carry out tasks with more ease and control.


The mechanism of action of Atrest 25 Tablet involves targeting the overactive secretion of neurotransmitters like serotonin, norepinephrine, and dopamine in the brain. When these chemicals are excessively produced, they can lead to nerve degeneration, resulting in the loss of control over thoughts, emotions, and movements. Atrest 25 Tablet works by regulating the levels of these natural substances in the brain, which play a crucial role in transmitting signals between nerves. By reducing the overactivity of these neurotransmitters, the medication helps to decrease the excessive brain signals that trigger involuntary muscle movements.


In summary, Atrest 25 Tablet offers valuable benefits in managing chorea symptoms associated with Huntington's disease by controlling jerky movements and enhancing the quality of life for individuals affected by this movement disorder. Its ability to modulate neurotransmitter levels in the brain results in a reduction of involuntary muscle movements, thus providing relief and improving overall daily functioning.


How to use the Atrest 25 Tablet

To use Atrest 25 Tablet, follow your doctor's instructions carefully. Take the medicine in the dose and duration prescribed by your physician. Swallow the tablet whole with water; do not crush, chew, or break it. Atrest 25 Tablet can be taken with or without food, but it is recommended to take it at the same time every day. Your doctor will determine the appropriate dosage and duration based on factors like your age, weight, and medical condition. Make sure to follow your doctor's guidance to get the best results from Atrest 25 Tablet.


Uses of Atrest 25 Tablet

Atrest 25 Tablet is commonly used for treating chorea, a movement disorder often associated with Huntington's disease. It effectively helps manage the hyperkinetic motor disorders that are characteristic of Huntington's chorea, which is an inherited neurodegenerative condition. By reducing the jerky, irregular, and uncontrollable movements experienced by individuals affected by Huntington's disease, Atrest 25 Tablet plays a vital role in improving the quality of life for those living with this challenging condition.


What conditions Atrest 25 Tablet treats?

Atrest 25 Tablet is used to treat Huntington's disease, a condition where the brain produces excessive natural substances leading to uncontrolled body movements. The tablet works by reducing these excess chemicals that affect muscle and nerve function. Symptoms include sudden, shaky movements, dizziness, decreased appetite, and difficulty speaking or swallowing. This genetic disease is inherited from ancestors or family members but not everyone develops it.


Should you consult a doctor?

If you experience symptoms like those of Parkinson's disease after taking Atrest 25 Tablet, such as tremors or muscle stiffness, it's important to seek medical help. Additionally, if you have been diagnosed with depression that is either untreated or difficult to manage, or if you are having active thoughts of harming yourself, you should consult a doctor promptly. It is also crucial to see a healthcare provider if you have pheochromocytoma, a tumor of the adrenal gland, or if you have prolactin-dependent tumors like pituitary or breast cancer. Before starting Atrest 25 Tablet, inform your doctor if you have a slow or intermediate metabolism of the enzyme CYP2D6, which affects how medications are processed, or if you have an intolerance to sugars like lactose. These conditions may require special attention or adjustments to your treatment plan.


Side effects of Atrest 25 Tablet

When taking Atrest 25 Tablet, some individuals may experience side effects as their body gets used to the medication. These side effects are usually mild and will go away on their own without medical intervention. Some common side effects include nausea, difficulty sleeping (insomnia), anxiety, fatigue, sleepiness, restlessness (akathisia), and depression. In some cases, you may also notice mental changes like confusion or hallucinations, muscle stiffness, fever, drowsiness (especially with higher doses), Parkinson-like symptoms such as uncontrollable movements, increased anxiety, difficulty swallowing (dysphagia), gastrointestinal issues like nausea, vomiting, diarrhea, or constipation, excessive sweating, low blood pressure, and signs of Neuroleptic malignant syndrome (a severe reaction) like mental changes, muscle stiffness, and changes in body temperature. If you experience feelings of sadness or depression, have suicidal thoughts, or have any intentions of hurting yourself, it is crucial to stop taking Atrest 25 Tablet immediately and seek medical help. It's important to consult your doctor if any side effects persist or if you have concerns about them.


Safety advice

scroll

liver

Atrest 25 Tablet should be avoided by individuals with liver disease as it is considered unsafe for use in such patients. It is important to consult with your doctor regarding the safety of using Atrest 25 Tablet if you have liver issues. Taking precautionary measures in this regard is crucial for your health and well-being.

scroll

kidney

Limited data exists concerning Atrest 25 Tablet use in kidney disease patients. It is advisable to consult your doctor regarding safety. Use caution in these cases.

scroll

alcohol

When consuming Atrest 25 Tablet, be aware that it can lead to increased drowsiness when combined with alcohol.

scroll

driving

When taking Atrest 25 Tablet, be cautious as it may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if experiencing these effects to ensure safety on the road.

scroll

pregnancy

Atrest 25 Tablet may not be safe to use during pregnancy. Limited human studies and animal studies suggest potential harm to the baby. Consult your doctor for guidance on the risks and benefits before considering its use.

scroll

breastfeeding

Caution advised when breastfeeding while using Atrest 25 Tablet, as limited data indicates potential harm to the baby through breastmilk transmission.


Age above 75(Geriatrics)

Atrest 25 Tablet should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking Atrest 25 Tablet.


Age below 6 months(Pediatrics)

Atrest 25 Tablet is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking Atrest 25 Tablet.


Consumption warning before consuming Atrest 25 Tablet

Before taking Atrest 25 Tablet, be aware of potential side effects like unusual changes in mood or behavior, restlessness, and feelings of nervousness or irritability. If you experience dizziness, remember to move slowly from sitting to standing positions. Regularly visit your doctor to monitor your progress and report any new symptoms or side effects promptly. Atrest 25 Tablet can cause severe depression and increase the risk of suicidal thoughts; avoid taking it with medications like risperidone or MAO inhibitors. Refrain from using Atrest 25 Tablet if you are severely depressed and currently undergoing treatment with antidepressants. Take precautions and prioritize your well-being before consuming Atrest 25 Tablet.


Disease interactions

Atrest 25 Tablet can have interactions with certain health conditions. Individuals with arrhythmias, which is an irregular heartbeat, should avoid using this medication. Similarly, those suffering from depression, liver disease, kidney disease, and Huntington's disease - an inherited condition that leads to the breakdown of nerve cells in the brain - should also refrain from taking Atrest 25 Tablet . It is essential for patients with these conditions to consult their healthcare provider before considering the use of this medication to prevent any potential adverse effects.


What if you forgot to take Atrest 25 Tablet?

If you forget to take a dose of Atrest 25 Tablet, take it as soon as you remember. But if it's nearly time for your next scheduled dose, just skip the missed one and continue with your regular dosing routine. It's important not to take a double dose to make up for the missed one. This ensures the proper spacing of doses and reduces the risk of any potential side effects.


What happens if you take overdose of Atrest 25 Tablet?

In the case of an overdose of Atrest 25 Tablet, it is crucial to seek immediate medical assistance by consulting a doctor or heading to the nearest hospital. An overdose can result in various symptoms, including uncontrollable muscle spasms affecting different parts of the body, uncontrolled rolling of the eyes, excessive blinking, nausea, vomiting, diarrhea, sweating, dizziness, sensation of coldness, confusion, hallucinations, drowsiness, redness or inflammation, and tremors. If you suspect an overdose or experience any of these symptoms, do not hesitate to seek help to ensure prompt and proper treatment.


Additional Information

Habit FormingNo
Chemical ClassTetrahydroisoquinoline Derivative
Therapeutic ClassNEURO CNS
Action ClassMonoamine depletor- Tetrabenazine

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

381.46

Inclusive of all taxes

Content verified by

chevron-right

Dr. Preeti Kumar

MBBS, DGO - Obstetrics and Gynaecology, DNB - Obstetrics and Gynaecology

Last update on 01-Oct-2024