Amfos 500mg Injection

By Amfos

Rx

1 Injection in a Vial

Composition icon

Composition

Amifostine(500mg)

Manufacturer - Vhb Life Sciences Inc icon

Manufacturer - Vhb Life Sciences Inc

50-AB, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India

Expires on or after icon

Expires on or after

August, 2025

About Amfos 500mg Injection

Amfos 500mg Injection, a medication used to manage dryness in the mouth following radiotherapy for head and neck cancer, also serves to lessen the harmful impact of cisplatin chemotherapy on the kidneys during cancer treatment. Administered as an IV infusion under the supervision of a doctor, the dosage and frequency are determined by your doctor based on your specific treatment needs. It is crucial to adhere strictly to your doctor’s instructions to prevent any severe side effects that may occur from improper usage or overdose.

The benefits of Amfos 500mg Injection may take time to manifest, sometimes requiring several weeks or months. It is important not to discontinue the medication without your doctor's advice. Some common side effects, such as nausea, vomiting, decreased blood pressure, sleepiness, dizziness, and flushing, may be experienced. If these effects persist or become bothersome, consulting your doctor is recommended. Maintaining hydration before taking the medication is advised.

Prior to starting Amfos 500mg Injection, inform your doctor about any heart conditions like irregular heartbeat or heart failure, as well as any other medications you are currently using, including those to manage infections. Regular monitoring of your blood pressure will occur both before and during the infusion process. Due to the potential interactions with other medications, it is essential to keep your healthcare team informed about all drugs you are taking.


Benefits

Amfos 500mg Injection offers multiple benefits to patients undergoing treatment for certain medical conditions. One key benefit is its effectiveness in reducing dryness in the mouth following radiotherapy for head and neck cancer. This common side effect can be quite uncomfortable, but Amfos 500mg Injection helps alleviate the discomfort, improving the patient's quality of life during recovery. Additionally, this medication plays a crucial role in protecting the kidneys from potential damage caused by cisplatin, a chemotherapy drug commonly used in the treatment of ovarian cancer. By safeguarding the kidneys, Amfos 500mg Injection ensures that patients can continue their cancer treatment without risking additional complications. It is essential to note that Amfos 500mg Injection should only be administered by healthcare professionals to ensure proper dosage and monitoring. Overall, the benefits of Amfos 500mg Injection extend beyond symptom relief, offering vital support to patients navigating through challenging cancer treatments.


How to use the Amfos 500mg Injection

When it comes to using Amfos 500mg Injection, it is important to follow your doctor's or nurse's instructions carefully. This medicine should only be administered by a healthcare professional, so it is essential not to attempt to self-administer it. Your doctor or nurse will determine the correct dosage and frequency of the injections based on your specific medical condition. They will inject the medicine into a muscle or vein, and it is crucial to receive the injection exactly as directed. If you have any questions or concerns about how to use Amfos 500mg Injection, do not hesitate to discuss them with your healthcare provider. Remember, this medication should only be administered by a trained professional for your safety and well-being.


Uses of Amfos 500mg Injection

Amfos 500mg Injection is primarily used in the treatment of dryness in the mouth that occurs as a result of undergoing radiotherapy for head and neck cancer. This injection helps to alleviate the discomfort and dry feeling in the mouth that may result from the side effects of radiotherapy. By targeting this specific issue, Amfos 500mg Injection aims to provide relief and improve the overall quality of life for individuals facing this challenge. It is important to follow the prescribed dosage and administration guidance provided by healthcare professionals to ensure the best possible outcome in managing dryness in the mouth post-radiotherapy.


What conditions Amfos 500mg Injection treats?

Amfos 500mg Injection is used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer. It protects the kidneys from harmful effects of chemotherapy medicine cisplatin in patients receiving this treatment for ovarian cancer. It is administered by a healthcare professional and should not be self-administered.


Should you consult a doctor?

If you experience persistent nausea, vomiting, decreased blood pressure, hiccups, sleepiness, dizziness, flushing, fever, or chills while using Amfos 500mg Injection, it is important to seek medical advice. These symptoms may indicate potential serious side effects that require attention from your healthcare provider. It is also crucial to consult with your doctor if the side effects do not go away or if they bother you. Additionally, if you have any underlying heart conditions such as irregular heartbeat or heart failure, or if you are taking medications for infections, inform your doctor before starting Amfos 500mg Injection. Regular monitoring of your blood pressure before and during the infusion is recommended to ensure your safety during treatment. If you have any concerns about the effects of this medicine, do not hesitate to discuss them with your healthcare team. Your doctor will determine the appropriate course of action based on your individual circumstances.


Side effects of Amfos 500mg Injection

When using Amfos 500mg Injection, you may experience certain side effects. Most of these side effects are temporary and fade away as your body gets used to the medication. Some common side effects include nausea, vomiting, decreased blood pressure, hiccups, sleepiness, dizziness, flushing (a warm feeling in the face, ears, neck, and trunk), fever, and chills. It is important to consult your doctor if these side effects persist or if you have any concerns about them.


Safety advice

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liver

Limited information is available on the use of Amfos 500mg Injection in patients with liver disease. It is important to consult your doctor before using this medication to ensure it is safe for you.

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kidney

Amfos 500mg Injection may be safe for use in patients with kidney disease. Available data indicates that dose adjustment for kidney issues may not be necessary. It is advisable to consult your doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Amfos 500mg Injection.

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driving

Caution should be exercised when driving if you are unsure of how Amfos 500mg Injection affects you. Avoid driving if you have symptoms that impact focus and reaction time.

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pregnancy

Amfos 500mg Injection may not be safe to use during pregnancy. Limited human studies suggest potential harm to the developing baby based on animal studies. Your doctor will consider the benefits and risks before prescribing. Please consult your doctor.

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breastfeeding

Amfos 500mg Injection is likely safe while breastfeeding. Human data shows no significant risk to the baby.


Consumption warning before consuming Amfos 500mg Injection

Before consuming Amfos 500mg Injection, it is important to be aware of certain considerations. This medication is primarily used to prevent dryness in the mouth post-radiotherapy for head and neck cancer and to reduce the harmful effects of chemotherapy on the kidneys during cisplatin treatment. It is administered through an injection into a vein under medical supervision. The dosage and frequency will be determined by your doctor based on your specific condition, and it is crucial to strictly adhere to their instructions to avoid severe side effects.


Common side effects of Amfos 500mg Injection include nausea, vomiting, decreased blood pressure, dizziness, and flushing. If these symptoms persist or become bothersome, consult your doctor promptly. It is recommended to maintain proper hydration before taking this medication. Additionally, individuals with heart conditions or those on medications for infections should inform their doctor before starting Amfos 500mg Injection. Regular blood pressure monitoring is necessary during the infusion process.


It is essential to discuss all current medications with your healthcare provider, as interactions can occur. The benefits of Amfos 500mg Injection may take time to manifest, so continue treatment as directed unless otherwise advised by your doctor.


Additional Information

Habit FormingNo
Chemical ClassPhosphorylated aminosulfhydryl compound
Therapeutic Class-
Action ClassCytoprotective agents- Kidney & Salivary gland

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024