Alsatinib Tablet
By Alsatinib
Rx
30 Tablet in a Bottle

Composition
Dasatinib(100mg)

Manufacturer - Alkem Laboratories Ltd
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after
September, 2025
About Alsatinib Tablet
Alsatinib Tablet, also known as Alsatinib Tablet 30's, is an anti-cancer medication used in the treatment of leukemia, a type of blood cancer. Leukemia is characterized by the excessive production of immature white blood cells by the bone marrow, leading to a decrease in the body's ability to fight infections. Alsatinib Tablet 30's is specifically indicated for chronic myelogenous leukemia (CML) patients who are resistant or intolerant to previous therapy, including those in chronic, accelerated, or blast phases. Additionally, it is used in newly diagnosed chronic Ph+ CML and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).
The active ingredient in Alsatinib Tablet 30's is Dasatinib, which belongs to the class of kinase inhibitors. Dasatinib works by inhibiting the action of abnormal proteins that promote the growth and multiplication of cancerous cells. By blocking these proteins, Dasatinib helps to slow down the abnormal growth of cancer cells, reducing their spread to other parts of the body.
It is important to take Alsatinib Tablet 30's exactly as prescribed by your doctor. The dosage will be determined based on the severity of your condition and may be adjusted over time. It is recommended to take the medication at the same time each day to maximize its benefits. While it may take several weeks or months to see the effects of Alsatinib Tablet 30's, it is crucial not to stop taking it without consulting your doctor.
Common side effects of Alsatinib Tablet 30's may include nausea, vomiting, abdominal pain, skin rash, fatigue, headache, and musculoskeletal pain. In some cases, it may also cause reduced platelet count, diarrhea, dizziness, gastrointestinal bleeding, muscle inflammation, myalgia, and difficulty breathing. Most side effects are temporary and do not require medical attention, but if they persist or worsen, it is advisable to seek medical advice.
It is important to note that Alsatinib Tablet 30's may interact with other medications and can also affect or be affected by them. Therefore, it is essential to inform your healthcare team about all the medicines you are taking. Alsatinib Tablet 30's is not recommended during pregnancy or while breastfeeding due to potential risks of embryo-fetal toxicity. Caution should be exercised if you have a history of liver or kidney disease, gastrointestinal disorders, cardiac problems, or myelosuppression before starting treatment with Alsatinib Tablet 30's. Additionally, if you experience dizziness or blurred vision while taking this medication, it is advisable to avoid driving. Regular monitoring of blood pressure and blood cell counts may be required during treatment.
Benefits
Alsatinib Tablet is a powerful medication used in the treatment of blood cancer, particularly Chronic Myeloid Leukemia (CML). This type of cancer affects the blood-forming tissues and weakens the body's ability to fight infections. Alsatinib Tablet contains Dasatinib, a kinase inhibitor that targets and inhibits the action of abnormal proteins, such as BCR-ABL tyrosine kinase, responsible for the rapid multiplication of cancer cells. By doing so, Alsatinib Tablet effectively kills or halts the growth of cancer cells in the body, preventing their further spread to other organs.
One of the key benefits of Alsatinib Tablet is its ability to stop the abnormal growth of cancer cells, thereby limiting the progression of the disease. By taking this medication as prescribed by a healthcare provider, patients can experience a reduction in cancer cell activity and a decrease in the risk of complications associated with CML. It is important to note that Alsatinib Tablet is a potent and potentially toxic medicine, so it is crucial to have a detailed discussion with a doctor about the risks and benefits before starting treatment.
Moreover, Alsatinib Tablet not only combats cancer cells but also helps in preventing their further multiplication. This dual action of killing existing cancer cells while inhibiting the growth of new ones showcases the effectiveness of Alsatinib Tablet in managing CML. Additionally, patients undergoing treatment with Alsatinib Tablet are advised to avoid alcohol consumption and maintain proper hydration by drinking plenty of water. These lifestyle modifications can further enhance the efficacy of the medication and support patients in their fight against blood cancer.
In conclusion, Alsatinib Tablet offers significant benefits in the treatment of Chronic Myeloid Leukemia by targeting cancer cells at their source and impeding their proliferation. By following a healthcare provider's guidance and adhering to the recommended precautions, patients can experience improved outcomes and a better quality of life while managing this challenging condition.
How to use the Alsatinib Tablet
To use Alsatinib Tablet, follow your doctor's guidance on dosage and duration. Swallow the tablet whole with a glass of water, without chewing, crushing, or breaking it. You can take Alsatinib Tablet with or without food, but try to take it at the same time every day for better results. Remember to not exceed the prescribed dose given by your doctor. It is important to take the medication as directed to ensure its effectiveness and to avoid any potential side effects. If you have any questions or concerns about how to use Alsatinib Tablet, consult your healthcare provider for clarification.
Uses of Alsatinib Tablet
Alsatinib Tablet is primarily used to treat specific types of blood cancer, including Chronic Myeloid Leukaemia (CML) and Acute Lymphoblastic Leukaemia (ALL) that are positive for the Philadelphia chromosome. This medication targets these types of cancers and helps in managing the disease. It is important to follow the prescribed dosage and frequency as advised by the healthcare provider to effectively benefit from the treatment.
What conditions Alsatinib Tablet treats?
Alsatinib Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (CML) and Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (ALL). These are types of blood cancers that affect the body's ability to fight infections. In CML, the Philadelphia chromosome causes abnormal production of white blood cells in the bone marrow, leading to symptoms like fatigue and weight loss. Similarly, in ALL, the BCR-ABL protein triggers the production of abnormal white blood cells, resulting in symptoms such as fever and bruising.
Should you consult a doctor?
If you experience persistent side effects like abdominal pain, anemia, breathing problems, fatigue, fever, headache, infection, low blood platelets, musculoskeletal pain, nausea, rash, or vomiting while taking Alsatinib Tablet, it is essential to seek medical attention promptly. Additionally, consult your doctor if you encounter increased heartbeat, low or high blood pressure, or if you feel dizzy or experience blurred vision during treatment. Regular blood tests are necessary to monitor your blood cell count, as this medicine can affect the blood cells. Contact your healthcare provider immediately if you have concerns about the side effects or if they do not improve over time. Moreover, inform your doctor about all medications you are taking to avoid any potential interactions. It is crucial to avoid driving if you experience dizziness or blurred vision while using this medication. Alsatinib Tablet is not recommended for use during pregnancy or breastfeeding.
Side effects of Alsatinib Tablet
When taking Alsatinib Tablet, some individuals may experience certain side effects. These effects are usually temporary and tend to fade as your body gets used to the medication. However, if any of the following side effects persist or cause concern, it is advisable to consult your doctor for guidance. Possible side effects of Alsatinib Tablet may include abdominal pain, anemia (low red blood cell count), breathing difficulties, fatigue, fever, headache, infections, low blood platelet levels, musculoskeletal pain (affecting bones, muscles, or joints), nausea, rash, vomiting, diarrhea, decreased platelet count, edema, back pain, dizziness, skin rash, difficulty breathing, gastrointestinal bleeding, and myalgia. If you experience any of these side effects, particularly if they become bothersome or persistent, seek medical advice promptly.
Safety advice

liver
Alsatinib Tablet is considered safe for use in patients with liver disease. It is reassuring that no dose adjustment of Alsatinib Tablet is necessary in such cases. This indicates that the medication is well-tolerated by individuals with liver issues, providing a sense of security regarding its effects on the liver. It is important to follow the prescribed dosage and regimen as directed by your healthcare provider to ensure the safe and effective use of Alsatinib Tablet in individuals with liver disease.

kidney
Alsatinib Tablet is considered safe for use in patients with kidney disease. Current data shows that dosage adjustment may not be necessary. It is advisable to seek advice from your doctor.

alcohol
Consult your doctor when consuming alcohol with Alsatinib Tablet.

driving
Take caution when driving while using Alsatinib Tablet. Side effects like dizziness and blurred vision may impair your ability to drive safely.

pregnancy
Alsatinib Tablet is not safe to use during pregnancy due to potential risk to the developing baby. It may only be prescribed in life-threatening situations if benefits outweigh risks. Consult your doctor before using.

breastfeeding
Alsatinib Tablet is considered unsafe to use while breastfeeding due to potential toxicity risk to the baby.
Consumption warning before consuming Alsatinib Tablet
Before consuming Daslemia 100mg Tablet 30's, it's crucial to note certain warnings. Firstly, if you have any allergies to this medication or its components, avoid using it. Inform your doctor about your medical history, especially if you have liver/kidney issues, diabetes, heart problems, high blood pressure, or gastrointestinal disorders. Using Daslemia 100mg Tablet 30's in such conditions may result in severe side effects. This medicine can lead to myelosuppression, fluid retention, gastrointestinal bleeding, QT prolongation, and heart conditions like congestive heart failure and myocardial infarction. It is also known to cause harm to the unborn baby, so let your doctor know if you are pregnant or planning to conceive. Breastfeeding should be stopped during the treatment. Only administer Daslemia 100mg Tablet 30's to children over one year old under medical supervision. Refrain from alcohol and smoking to avoid adverse effects.
Disease interactions
Before taking Daslemia 100mg Tablet 30's, it is important to inform your doctor if you have kidney or liver disease, gastrointestinal disorders, diabetes, or cardiac disorders. These medical conditions may interact with the medication and warrant special attention. By discussing your health history with your healthcare provider, they can determine the compatibility of Daslemia 100mg Tablet with your specific health situation. This proactive approach helps ensure the safe and effective use of the medication tailored to your individual needs.
What if you forgot to take Alsatinib Tablet?
If you happen to miss a dose of Alsatinib Tablet, it is best to simply skip the missed dose and resume your regular dosing schedule. Avoid trying to make up for the missed dose by taking a double dose, as this can lead to potential side effects or complications. It is important to stick to the recommended dosing instructions to ensure the effectiveness and safety of the medication.
Related lab tests
For patients taking Alsatinib Tablet, it is important to monitor their response to the treatment and ensure safety. The following lab tests are commonly recommended for individuals on Alsatinib Tablet:
1. Bcr-Abl Gene Translocation (Qualitative): This test helps in detecting the presence of genetic mutations that can cause certain types of cancer, particularly leukemia. It provides qualitative information on the specific gene translocations involved.
2. Bcr-Abl Gene Translocation (Quantitative): Similar to the qualitative test, this test measures the quantity of the Bcr-Abl gene translocation. It helps in assessing the response to treatment and disease progression.
3. Complete Blood Count (CBC): This test provides valuable information about the different types of blood cells, such as red blood cells, white blood cells, and platelets. It helps in monitoring for any potential side effects of Alsatinib Tablet on blood cell counts.
4. Peripheral Smear Examination: This test involves examining a sample of blood under a microscope to evaluate the size, shape, and number of blood cells. It can help in diagnosing conditions such as anemia, infections, and blood disorders.
Regular monitoring through these lab tests can aid healthcare providers in adjusting the treatment plan as needed and ensuring the well-being of patients using Alsatinib Tablet.
Additional Information
Habit Forming | No |
Chemical Class | Pyrimidine and Thiazole Derivetive |
Therapeutic Class | - |
Action Class | Tyrosine kinase inhibitors |
FAQs
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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024