Advagraf 5mg Capsule PR
By Advagraf
Rx
10 Capsule PR in a Strip

Composition
Tacrolimus(5mg)

Manufacturer - Astellas Pharma Inc
Astellas Pharma India Pvt Ltd, 301, 3rd Floor, C and B Square, 127 Andheri Kurla Road, Chakala, Andheri East, Mumbai 400 069.

Expires on or after
August, 2025
About Advagraf 5mg Capsule PR
Advagraf 5mg Capsule PR is a medication used, in combination with other drugs, to help prevent the body from rejecting a newly transplanted organ such as the liver, kidney, or heart. It achieves this by reducing the body's immune response, thereby preventing it from attacking the organ. Belonging to a class of drugs called immunosuppressants, Advagraf 5mg Capsule PR plays a crucial role in organ transplant patients' post-surgery care.
The dosage of Advagraf 5mg Capsule PR and the frequency of intake are determined by factors such as the type of transplant, body weight, and other medications being taken. It is important to strictly adhere to the instructions provided by your doctor. It is recommended to take this medication on an empty stomach, at least 1 hour before or 2 hours after a meal. Consistent and regular intake is essential for optimal results, even if the individual feels well, as discontinuing the medication can elevate the risk of organ rejection.
While Advagraf 5mg Capsule PR is effective in preventing organ rejection, it may also lead to various side effects. These can include the onset or exacerbation of conditions like diabetes and kidney problems, which require immediate medical attention. Other common side effects may involve tremors, infections, high blood pressure, and insomnia. It is important to communicate any persistent or worsening side effects to your doctor. Notably, this medication weakens the immune system, making individuals more vulnerable to infections than usual.
Prior to taking Advagraf 5mg Capsule PR, it is crucial to inform your doctor about any existing kidney, liver, or heart issues, diabetes, high blood pressure, or other medications being consumed, particularly those related to infections, pain, or arthritis. Sun and ultraviolet (UV) light exposure should be limited while on this medication, as immunosuppressants heighten the risk of skin cancer development.
For individuals of both genders using this medication, effective birth control methods should be employed to avoid pregnancy. Generally, the use of Advagraf 5mg Capsule PR during pregnancy or while breastfeeding is not recommended unless absolutely necessary. Regular medical tests are required before and during treatment to monitor progress, and blood pressure levels need to be frequently checked to ensure optimal health.
Benefits
Advagraf 5mg Capsule PR is a medication that falls under the category of immunosuppressants, designed to prevent organ rejection in transplant patients. When a new organ is transplanted into your body, there is a risk of your immune system mistakenly attacking it. Advagraf works by weakening your immune response, which normally fights off infections, thereby reducing the likelihood of your body rejecting the transplanted organ. By taking Advagraf in combination with other medications as prescribed by your doctor, you significantly increase the chances of a successful transplant operation. It is crucial to follow your doctor's instructions and continue taking Advagraf as directed to ensure the best possible outcome. Do not discontinue the medication without consulting your doctor first.
How to use the Advagraf 5mg Capsule PR
To use Advagraf 5mg Capsule PR, it is important to follow the instructions provided by your doctor or those on the label. This medication should be taken on an empty stomach. It is important to take the capsule as directed, without food, to ensure its effectiveness. Be sure to carefully read and follow the dosage instructions to get the most benefit from this medication. If you have any questions or concerns about how to use Advagraf 5mg Capsule PR, do not hesitate to consult your doctor for further guidance.
Uses of Advagraf 5mg Capsule PR
Advagraf 5mg Capsule PR is primarily used for the prevention of organ rejection in transplant patients. This medication is specifically designed to help transplant patients maintain the function of their transplanted organ by suppressing the body's immune response that may reject the organ. By taking Advagraf 5mg Capsule PR as directed by a healthcare provider, transplant recipients can reduce the risk of their body attacking and potentially damaging the transplanted organ. It is important for patients to follow their prescribed dosage and schedule to ensure the effectiveness of this medication in preventing rejection.
What conditions Advagraf 5mg Capsule PR treats?
Advagraf 5mg Capsule PR is used to prevent organ rejection in transplant patients, such as those who have received a liver, kidney, or heart transplant. This medication works by weakening the body's immune system, which otherwise may attack the new organ. It is essential to take Advagraf as prescribed by your doctor, on an empty stomach, to maximize its benefits and reduce the risk of rejection. Potential side effects include diabetes, kidney problems, tremors, infections, high blood pressure, and insomnia. It is important to notify your doctor if you experience persistent or worsening side effects.
Should you consult a doctor?
Seek medical attention promptly if you experience symptoms such as increased glucose levels in the blood, kidney damage, insomnia, tremors, high blood pressure, or infections while taking Advagraf 5mg Capsule PR. These side effects require urgent medical care and should not be neglected. Inform your healthcare provider about any concerning symptoms that do not improve or worsen. Additionally, if you have kidney, liver, or heart issues, diabetes, or high blood pressure, or if you are taking other medications, consult your doctor before using Advagraf 5mg Capsule PR. It is vital to undergo regular medical tests and blood pressure monitoring throughout the treatment to ensure your well-being. Remember, it is crucial to take this medication as prescribed, even if you feel well, to prevent the risk of rejecting your transplanted organ.
Side effects of Advagraf 5mg Capsule PR
When taking Advagraf 5mg Capsule PR, some common side effects may occur, though most of them usually do not need medical treatment and will go away as your body gets used to the medication. However, if these side effects persist or cause concern, it is essential to consult your doctor promptly. Possible side effects of Advagraf 5mg Capsule PR include increased glucose levels in the blood, which may require monitoring for patients with diabetes or at risk of developing diabetes. Kidney damage is another potential side effect that can occur, emphasizing the importance of regular kidney function tests while on this medication. Insomnia, or difficulty in sleeping, may also be experienced by some individuals taking Advagraf 5mg Capsule PR, affecting their sleep patterns. Tremors, a shaky or trembling sensation in the body, can occur as a side effect, along with high blood pressure, which may need to be monitored regularly. Additionally, an increased risk of infection is a potential side effect of this medication, highlighting the importance of being vigilant for any signs of infection while taking Advagraf 5mg Capsule PR.
Safety advice

liver
Advagraf 5mg Capsule PR should be used carefully in individuals with liver disease. Adjusting the dose of Advagraf 5mg Capsule PR may be necessary in these cases. It is important to seek advice from your doctor before using this medication if you have any liver issues.

kidney
Use Advagraf 5mg Capsule PR carefully if you have kidney problems. Your doctor may adjust the dose. Make sure to consult your doctor.

alcohol
It is not safe to drink alcohol while taking Advagraf 5mg Capsule PR.

driving
Advagraf 5mg Capsule PR may reduce alertness, impact vision, or cause drowsiness and dizziness. Avoid driving if experiencing these effects.

pregnancy
Advagraf 5mg Capsule PR may not be safe during pregnancy, based on animal studies showing potential harm to the baby. Your doctor will assess the risks and benefits before prescribing. Please consult your doctor.

breastfeeding
Caution is advised when breastfeeding while using Advagraf 5mg Capsule PR as it may not be safe for the baby. Limited data indicates that the drug could pass into breastmilk and potentially harm the infant.
Consumption warning before consuming Advagraf 5mg Capsule PR
Before consuming Advagraf 5mg Capsule PR, it is crucial to be aware of certain important information for your safety. This medication is typically used in combination with other drugs to prevent your body from rejecting a newly transplanted organ, such as a liver, kidney, or heart. Advagraf 5mg Capsule PR functions by weakening your immune system to prevent it from attacking the new organ. It falls under a category of medications called immunosuppressants.
The dosage and frequency of taking Advagraf 5mg Capsule PR will vary based on the type of transplant, your body weight, and other medications you are using. It is vital to strictly adhere to your doctor's instructions. It is recommended to take this medication on an empty stomach, either at least 1 hour before or 2 hours after a meal. Continuous and consistent usage is important, even if you are feeling well, as discontinuation could elevate the risk of rejecting the transplanted organ.
Notably, this medication may have several potential side effects including the possibility of developing or exacerbating diabetes and kidney issues. Pay close attention if you experience tremors, infections, high blood pressure, or insomnia. If side effects persist or worsen, seek medical advice promptly. Advagraf 5mg Capsule PR can lower your immune system, making you more vulnerable to infections than usual.
Prior to taking this medicine, inform your doctor about any existing kidney, liver, heart, diabetes, or high blood pressure conditions. Disclose all other medications you are taking, particularly those for infections, pain, or arthritis, as they could interact with this medication. While using this medicine, limit your exposure to sunlight and UV light to lower the risk of skin cancer due to increased susceptibility with immunosuppressants. Both men and women on this medication should use effective contraception to avoid pregnancy unless absolutely necessary. Regular medical tests and close monitoring of blood pressure are essential during treatment.
What if you forgot to take Advagraf 5mg Capsule PR?
If you forget to take your dose of Advagraf 5mg Capsule PR, try to take it as soon as you remember. But if it's close to the time for your next scheduled dose, then it's best to skip the missed dose and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. Remember that consistency in taking your medication as prescribed is key to its effectiveness.
Additional Information
Habit Forming | No |
Chemical Class | Macrolide Lactams |
Therapeutic Class | - |
Action Class | Immunosuppressant- Calcineurin inhibitors |
FAQs
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₹5000
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Content verified by

Dr. Monie Riju Simon
MBBS - General Medicine
Last update on 11-Feb-2025