Adebile 450mg Tablet
By Adebile
Rx
10 Tablet in a Strip

Composition
Ursodeoxycholic Acid(450mg)

Manufacturer - Adelmo Healthcare
B-302, Aasopalav Apartments, Near D.R.M Office,Danteshwar Road,Vadodara,Gujarat-390004

Expires on or after
August, 2026
About Adebile 450mg Tablet
Adebile 450mg Tablet is a medication used to dissolve certain gallstones and prevent their formation. It is also utilized in the treatment of primary biliary cirrhosis, a type of liver disease. The main component of Adebile 450mg Tablet is ursodeoxycholic acid, a naturally occurring bile acid that helps reduce cholesterol production in the blood, aiding in the dissolution of gallstones primarily made of cholesterol.
When taking Adebile 450mg Tablet, it is important to swallow the tablet whole after a meal, accompanied by a glass of milk or water. The dosage will be determined based on the condition being treated and your body weight. Consistent usage is essential to achieve maximum benefits, so continue taking it for the duration prescribed by your healthcare provider, which may last several months or longer. Even if your symptoms improve, it is crucial to adhere to the prescribed regimen.
Potential side effects of Adebile 450mg Tablet may include abdominal pain, diarrhea, hair loss, itching, nausea, and rash, although not everyone will experience these effects. If these side effects are bothersome or persistent, it is advisable to inform your doctor promptly. Prior to initiating treatment with Adebile 450mg Tablet, disclose any history of gallbladder or bile duct inflammation, recurrent cramp-like upper abdominal pain, coughing up blood, or rapid weight gain to your healthcare provider. Interactions with other medications can occur, so ensure that your doctor is aware of all the medicines you are taking.
Regular monitoring during treatment with Adebile 450mg Tablet may involve ultrasound scans or frequent blood tests to assess liver function. Specific precautions include discontinuing hormonal birth control pills for women, as they can contribute to gallstone production. Individuals with variceal bleeding, ascites, liver encephalopathy, or pre-existing liver conditions should consult with their doctor before using Adebile 450mg Tablet. Additionally, it is advisable to avoid alcohol consumption while taking this medication to mitigate the risk of increased drowsiness and potential liver damage.
In summary, Adebile 450mg Tablet is a biliary agent with beneficial effects on gallstones and liver function, but it is essential to follow the prescribed regimen, report any side effects to your doctor, and provide comprehensive medical information prior to commencing treatment.
Benefits
Adebile 450mg Tablet offers various benefits in treating two specific conditions. Firstly, for individuals with Primary Biliary Cirrhosis, a liver disease that worsens over time, this medicine can help prevent or delay liver damage when taken early on. By using Adebile 450mg Tablet, either alone or in combination with other medications, individuals can improve their liver health and potentially avoid liver failure. To maximize the effectiveness of the treatment, it is recommended to maintain a healthy lifestyle by quitting smoking, maintaining a healthy weight, and limiting alcohol consumption. Continuation of this treatment is usually required for the long term.
Secondly, Adebile 450mg Tablet is also beneficial for individuals with gallbladder stones. By containing ursodeoxycholic acid, a naturally-occurring bile acid, this medication works to reduce the amount of cholesterol produced by the liver and aids in breaking down cholesterol stones in the gallbladder. Regular intake of Adebile 450mg Tablet, as prescribed by a doctor, can help dissolve these stones over time. In addition to medication, lifestyle modifications and other medications may be recommended by the healthcare provider to lower cholesterol levels and lower the risk of developing gallstones.
Overall, Adebile 450mg Tablet plays a crucial role in treating primary biliary cirrhosis and gallbladder stones by improving liver function, reducing cholesterol production, and promoting the breakdown of gallstones. It offers a significant advantage in managing these conditions and can lead to improved liver health and overall well-being when used consistently and as guided by a healthcare professional.
How to use the Adebile 450mg Tablet
To use Adebile 450mg Tablet effectively, it is important to follow your doctor's instructions carefully. Swallow the tablet as a whole with a glass of water, and make sure not to chew, crush, or break it. It is recommended to take Adebile 450mg Tablet with food. For the dispersible tablet form, dissolve it in water as directed on the label and consume it promptly after mixing. It is crucial to adhere to the prescribed dose and duration of treatment set by your doctor. Whether you are taking the tablet, capsule, or dispersible tablet, do not alter the form of the medication. Your doctor will determine the appropriate dose for you based on factors such as your age, weight, and the seriousness of your condition. It is essential to take Adebile 450mg Tablet for the entire prescribed period to achieve optimal results. If you experience that the effect of the medication is too strong or too weak, do not hesitate to consult your doctor for guidance. Always remember, the key is to follow your doctor's instructions for the best outcome.
Uses of Adebile 450mg Tablet
Adebile 450mg Tablet is used for treating primary biliary cirrhosis, a liver disease. It is also used for gallstones that may not be visible on X-ray in patients with a functioning gall bladder. Furthermore, this medication is effective in treating gallstones, primary biliary cholangitis, and biliary and liver diseases caused by cystic fibrosis, specifically in children aged 6 to 18 years.
What conditions Adebile 450mg Tablet treats?
Adebile 450mg Tablet is used to treat primary biliary cholangitis, an autoimmune disease that damages the bile ducts in the liver. This leads to a build-up of bile in the liver, causing liver damage. Additionally, the tablet is used in managing gallstones, which can cause abdominal pain and other digestive issues due to excess cholesterol in the bile. It can also be beneficial in cystic fibrosis, a hereditary condition impacting the digestive system and lungs by producing thick fluids that obstruct the pancreas and lungs.
Should you consult a doctor?
Seek a doctor if you experience any of the following conditions while taking Adebile 450mg Tablet: improper functioning of the gall bladder, have visible calcified gallstones on an x-ray, acute inflammation of the biliary tract or gall bladder, blockage of the cystic duct or common bile duct, or frequent cramp-like pains in the upper abdomen. Children with biliary atresia and poor bile flow should not use this medication without a doctor’s approval. It is crucial to consult your child’s doctor for the correct dosage and duration based on their weight, age, and medical condition. If any adverse effects or concerns arise, seek medical assistance promptly.
Side effects of Adebile 450mg Tablet
When taking Adebile 450mg Tablet, some individuals may experience side effects. While most of these side effects are usually temporary and will go away as your body gets used to the medication, it's important to consult your doctor if they persist or if you have concerns. Common side effects may include abdominal pain, diarrhea, hair loss, itching, nausea, and rash. In some cases, you may also experience abdominal discomfort, fever, cough, dizziness, indigestion, black or tarry stools, frequent and painful urination, weakness, soft or loose stools, and persistent diarrhea. If you encounter persistent diarrhea, it is advised to stop taking the medication immediately and seek medical attention from your doctor.
Safety advice

liver
Caution should be exercised when taking Adebile 450mg Tablet in cases of liver disease. Limited information is available regarding the use of this medication in patients with liver issues, therefore it is important to consult your doctor before starting the treatment. Your healthcare provider will be able to assess your specific situation and provide the most appropriate guidance.

kidney
Limited data is present on the use of Adebile 450mg Tablet in kidney disease patients. Please consult your doctor for guidance.

alcohol
When using Adebile 450mg Tablet, be cautious as it can lead to increased drowsiness when consumed with alcohol.

driving
When taking Adebile 450mg Tablet, it is usually safe to drive as it does not typically affect your driving abilities.

pregnancy
Adebile 450mg Tablet is generally safe during pregnancy. Animal studies show minimal negative effects on the baby, but human studies are limited.

breastfeeding
Adebile 450mg Tablet is likely safe for breastfeeding mothers based on limited human data that shows no significant risk to the baby.
Age above 75(Geriatrics)
Adebile 450mg Tablet can be used in elderly patients. However, consult with your doctor before taking Adebile 450mg Tablet.
Consumption warning before consuming Adebile 450mg Tablet
Before consuming Adebile 450mg Tablet, take caution if you have allergies to any of its components, gallbladder or bile duct inflammation, blockages, biliary colic, or calcified gallstones. Notify your doctor if you experience variceal bleeding, ascites, liver encephalopathy, or liver disease. Consult your doctor before combining Adebile 450mg Tablet with certain medications as it may impact their absorption or effectiveness. Avoid Adebile 450mg Tablet during pregnancy or breastfeeding unless advised. Children over 6 years can take Adebile 450mg Tablet under medical supervision. Refrain from alcohol consumption with this medication to prevent drowsiness and liver issues. Keep your healthcare provider informed about your health status and ongoing treatments to prevent adverse reactions.
Disease interactions
When taking Adebile 450mg Tablet, it is crucial to inform your doctor if you have biliary obstruction, liver impairment, variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), or liver encephalopathy. These conditions can interact with the medication and may require adjustments in dosage or additional monitoring to ensure the effectiveness and safety of the treatment. It is important for your healthcare provider to have a comprehensive understanding of your medical history and current health status to mitigate any potential adverse effects or contraindications that could arise from the interaction between the disease conditions and Adebile 450mg Tablet.
What if you forgot to take Adebile 450mg Tablet?
If you forget to take a dose of Adebile 450mg Tablet, do not worry. Simply skip the missed dose and go back to your regular dosing schedule. It is important not to take a double dose to make up for the missed one. Taking extra medication can increase the risk of side effects without providing any additional benefits. Just continue with your next scheduled dose as usual. This will help ensure that you maintain a consistent level of the medication in your body for optimal effectiveness.
What happens if you take overdose of Adebile 450mg Tablet?
If someone takes more Adebile 450mg Tablet than prescribed, this is known as an overdose. In case of an overdose, it's important to seek medical help promptly by contacting your doctor or going to the nearest hospital. The main symptom of an overdose of Adebile 450mg Tablet is experiencing diarrhoea. If you or anyone you know experiences diarrhoea after taking too much of this medication, it is crucial to seek immediate medical attention to address the situation effectively.
Related lab tests
When taking Adebile 450mg Tablet, it is important to monitor your liver health through various lab tests to ensure the medication is working effectively and not causing any harm to your liver. The following related lab tests are recommended:
1. Liver Function Tests: These tests include measuring various enzymes and proteins in your blood that can indicate how well your liver is functioning.
2. Complete Blood Count: This test measures the amount of different types of blood cells in your body, which can give insight into your overall health and detect any abnormalities that may be affecting your liver.
3. Gall Bladder Scan: This imaging test specifically focuses on the gallbladder, which is closely related to liver health. It can help detect any issues with the gallbladder that may impact liver function.
Regularly monitoring these lab tests while taking Adebile 450mg Tablet can help healthcare providers track your liver health and make any necessary adjustments to your treatment plan.
Additional Information
| Habit Forming | No |
| Chemical Class | Bile Acids and Salts |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Hepatoprotectives |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024


