Nizonide-O Tablet

By Nizonide-O

Rx

10 Tablet in a Strip

Composition icon

Composition

Nitazoxanide(500mg) + Ofloxacin(200mg)

Manufacturer - Lupin Ltd icon

Manufacturer - Lupin Ltd

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Expires on or after icon

Expires on or after

April, 2026

About Nizonide-O Tablet

Nizonide-O Tablet is a combination medication used for the treatment of diarrhea and dysentery. It works by preventing the growth of harmful microorganisms in the body, thus helping to effectively treat infections. This prescription medicine should be taken as directed by your doctor. It can be taken with or without food, but it is important to take it at the same time each day for optimal results. Avoid exceeding the recommended dosage, as an overdose can have adverse effects on your health. If you miss a dose, take it as soon as you remember.

It is essential to complete the full course of treatment with Nizonide-O Tablet, even if you start feeling better, to ensure a complete recovery. While taking this medicine, you may experience side effects such as nausea, vomiting, stomach pain, loss of appetite, and headache. To manage these side effects, maintain a healthy diet and stay hydrated. If any side effects worsen, contact your doctor promptly. In case of allergic reactions like rashes, itching, swelling, or difficulty breathing, seek immediate medical help.

Before initiating treatment with Nizonide-O Tablet, inform your doctor about any liver or kidney issues you may have, as well as any other medications you are currently taking. Pregnant or breastfeeding women should consult their healthcare provider before using this medication. Consumption of alcohol while on Nizonide-O Tablet should be avoided, as it can lead to increased dizziness. While this medicine typically does not affect your ability to drive, refrain from driving if you feel drowsy or lightheaded. If you have known allergies to the components of this medicine, do not use it and seek medical advice.

NIZONIDE 500MG TABLET, containing Nitazoxanide, is categorized as an Antiprotozoal medication and is specifically used to treat diarrhea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhea occurs when there is an imbalance in fluid secretion in the stool. It is important to note that NIZONIDE 500MG TABLET is not effective for treating diarrhea caused by C. parvum in HIV-infected or immunodeficient patients. Individuals with kidney, liver, or biliary issues should inform their doctor before starting this medication.

This medicine should be used cautiously by pregnant and breastfeeding women, as there is limited safety data available. It is not recommended for children under 11 years of age, and elderly patients above 65 years should use it with caution. Common side effects of NIZONIDE 500MG TABLET include abdominal pain, diarrhea, headache, and nausea. If any of these symptoms worsen, contact your healthcare provider for guidance.


Benefits

Nizonide-O Tablet, containing the antibiotic Ofloxacin, offers several benefits in treating bacterial infections. This medication is effective against a wide range of bacteria, including most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria that don't require oxygen to survive. By being bactericidal, Ofloxacin works to eliminate the infection-causing bacteria by disrupting the formation of their cell wall crucial for their survival. Additionally, it hinders the repair process of bacterial cells, ultimately leading to the destruction of the bacteria.


One significant advantage of Nizonide-O Tablet is its ability to penetrate deeply into various tissues and body fluids. This characteristic makes it a suitable choice for treating infections that extend into deep tissues and bones. Its ability to reach these areas ensures thorough treatment, targeting the infection at its source and aiding in a more effective and comprehensive recovery process.


Overall, the benefits of Nizonide-O Tablet lie in its broad spectrum of bacterial coverage, bactericidal action, and excellent tissue penetration properties, all of which contribute to its effectiveness in treating a variety of bacterial infections, particularly those affecting deep tissues and bones.


How to use the Nizonide-O Tablet

To use Nizonide-O Tablet, follow your doctor's instructions carefully. Swallow the tablet whole with a glass of water. It can be taken with or without food, but try to take it at the same time every day. Avoid chewing, crushing, or breaking the tablet. If you are prescribed the syrup form, shake the bottle well before use and measure the dose using the provided measuring cup, dosing syringe, or dropper. Take Nizonide-O Tablet exactly as directed by your physician. Do not alter the dosage or stop taking the medication unless advised by your doctor, who will determine the right dose and duration based on your age, weight, and medical condition. If you have any questions or concerns about how to use Nizonide-O Tablet, consult your healthcare provider.


Uses of Nizonide-O Tablet

Nizonide-O Tablet is used for the treatment and prevention of bacterial infections in adults. This medication works effectively by stopping the growth of bacteria, thereby treating the infection. It is important to take the prescribed dose as directed by the healthcare provider to ensure the best results. This tablet is commonly used to combat various bacterial infections, helping individuals recover and prevent the spread of harmful bacteria in the body. By adhering to the recommended dosage and treatment regimen, the Nizonide-O Tablet can be beneficial in managing bacterial infections successfully.


What conditions Nizonide-O Tablet treats?

A bacterial infection occurs when harmful bacteria invade the body, multiplying and causing illness. Symptoms include fevers, chills, and fatigue, affecting various body parts rapidly. Bacteria come in different shapes, such as spherical, rod, and spiral forms. Infections range from minor issues like sore throats to serious conditions like meningitis. Common bacteria causing infections are Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but those with weak immune systems or on immunosuppressive medication are at higher risk.


Should you consult a doctor?

It is crucial to seek medical attention if you experience any of the following conditions before taking Nizonide-O Tablet:

- History of fits or at risk of seizures

- Previous swelling of tendons affecting the wrist or Achilles tendon

- Glucose-6-dehydrogenase deficiency or family history of the condition


Additionally, inform your doctor if you have:

- Connective tissue issues like Marfan syndrome

- Turner syndrome or a genetic disorder

- Sjogren’s syndrome, an autoimmune disease

- Myasthenia gravis causing muscle weakness

- Diabetes

- Imbalance in salt levels

- Any previous or existing mental health problems


Seeking medical advice in these situations is essential for safe and effective use of Nizonide-O Tablet.


Side effects of Nizonide-O Tablet

Nizonide-O Tablet may cause various side effects. Common side effects include nausea, vomiting, stomach pain, and headache. These side effects usually go away as the body gets used to the medication, but if they persist or cause concern, it's important to consult a doctor.


Other possible side effects of Nizonide-O Tablet include tendon rupture, joint pain, sleep problems, dizziness, itching, external genital itching in women, vaginal inflammation, taste changes, irritated or burning eyes, spinning sensations, agitation, cough, sore nose or throat, fungal infection, skin rash, loss of appetite, fast heartbeat, drowsiness, confusion, anxiety, nightmares, altered liver enzymes, sweating, changes in kidney function tests, low blood pressure, hives, and rash with pimples.


In rare cases, serious side effects may occur, requiring immediate medical attention. These include treatment resistance, allergic reactions (such as severe rash, difficulty breathing, swelling), watery diarrhoea with blood, swollen tendons, nerve damage, vision changes, anaemia, blood cell abnormalities, skin conditions like erythema multiforme and toxic epidermal necrolysis, kidney problems, hearing loss, liver issues, heart rhythm abnormalities, depression, Stevens-Johnson syndrome, lung swelling, muscle breakdown, pancreas inflammation, low blood sugar leading to loss of consciousness, eye inflammation, and others.


If you experience any of these severe side effects while taking Nizonide-O Tablet, stop the medication immediately and seek medical help. It's crucial to be aware of these potential side effects and act promptly if they occur.


Safety advice

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liver

Nizonide-O Tablet should be used with caution in patients with liver disease. If you have a history of liver diseases or conditions, it is important to take Nizonide-O Tablet carefully. Make sure to consult your doctor before using this medication. Your doctor may need to adjust the dose of Nizonide-O Tablet if you experience symptoms like nausea, vomiting, loss of appetite, dark-colored urine, or yellowing of the skin or eyes. Always follow your doctor's advice and instructions when taking this medication to ensure your safety, especially if you have liver issues.

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kidney

Nizonide-O Tablet needs caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor.

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alcohol

It is not safe to consume alcohol with Nizonide-O Tablet as it can harm your liver. It is advised to avoid alcohol while taking this medication.

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driving

"Nizonide-O Tablet may decrease alertness, affect vision, and cause drowsiness and dizziness. Refrain from driving if experiencing these symptoms. Nizonide-O Tablet can also impact alertness and coordination, so avoid driving or operating machinery needing focus."

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pregnancy

Nizonide-O Tablet is not recommended during pregnancy due to potential harm to the developing baby. Limited human studies and animal research suggest risks. Consult your doctor for a thorough evaluation of benefits versus risks.

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breastfeeding

Nizonide-O Tablet is not recommended during breastfeeding as it may pass into breastmilk and harm the baby. It's advised against taking it while nursing due to potential risks.


Age above 75(Geriatrics)

Nizonide-O Tablet should be used with caution by elderly patients. Consult your doctor before taking it.


Age below 6 months(Pediatrics)

Nizonide-O Tablet is not recommended for use by children and adolescents (under 18 years of age). Consult your doctor before taking it.


Consumption warning before consuming Nizonide-O Tablet

Before consuming Nizonide-O Tablet, refrain from its use if you have known allergies or have experienced severe reactions to ofloxacin or other similar antibiotics. This medication may heighten the risk of developing tendinitis or experiencing a tendon rupture. It is crucial to disclose any history of kidney, heart, or lung transplant, kidney complications, joint disorders such as rheumatoid arthritis, seizures, or participation in strenuous physical activities to your healthcare provider. Individuals with myasthenia gravis should be cautious as Nizonide-O Tablet can exacerbate muscle weakness, potentially leading to breathing difficulties or fatal outcomes. Avoid consuming dairy products along with this medication and minimize sun exposure to prevent increased sensitivity to sunlight. Patients with epilepsy or QT prolongation should inform their doctors before initiating treatment with Nizonide-O Tablet.


What if you forgot to take Nizonide-O Tablet?

If you forget to take a dose of Nizonide-O Tablet, try to take it as soon as you remember. But if it is close to the time for your next scheduled dose, just skip the missed one and continue with your usual dosing schedule. It's important not to take a double dose to make up for the missed one. This helps to maintain the correct level of the medicine in your system without increasing the risk of side effects. Remember to always follow your prescribed dosing instructions to ensure the medication works effectively.


What happens if you take overdose of Nizonide-O Tablet?

In the event of accidental ingestion of an excessive amount of Nizonide-O Tablet, it is crucial to seek medical help promptly by consulting your doctor or going to the nearest hospital. An overdose of this medication may result in various symptoms such as confusion, dizziness, loss of consciousness, seizures, and nausea. It is important to act quickly and seek professional medical assistance if an overdose is suspected to prevent any potential complications.


Related lab tests

In relation to Nizonide-O Tablet, some relevant lab tests include stool examination, bacterial culture, microscopic examination, and Complete Blood Count (CBC). Stool examination helps in detecting any abnormalities in the digestive system, while bacterial culture can identify the presence of harmful bacteria that may be causing infections. Microscopic examination involves analyzing samples under a microscope to detect any microscopic organisms or abnormalities. A Complete Blood Count (CBC) provides important information about the types and numbers of cells in the blood, which can indicate various health conditions. So, these lab tests play a crucial role in assessing and monitoring the effectiveness of Nizonide-O Tablet for the intended condition.


Additional Information

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 18-Nov-2024