Istamet XR Tablet
By Istamet
Rx
10 Tablet ER in a Strip

Composition
Sitagliptin(100mg) + Metformin(1000mg)

Manufacturer - Sun Pharmaceutical Industries Ltd
Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after
May, 2026
About Istamet XR Tablet
Istamet XR Tablet is a combination medication containing Sitagliptin and Metformin, both essential for controlling high blood sugar levels in individuals with type 2 diabetes mellitus. The purpose of this medication is to prevent severe complications associated with diabetes, such as kidney damage, blindness, heart attacks, or strokes. It is usually prescribed alongside other diabetes treatments and is most effective when taken in conjunction with a healthy diet and regular physical activity.
This tablet should be consumed regularly, at the same time each day, to achieve optimal benefits. It is recommended to take Istamet XR Tablet with meals to lower the risk of an upset stomach. The dosage prescribed will vary based on individual conditions, blood sugar levels, and concurrent medications. Patients are advised not to discontinue usage unless instructed by their healthcare provider. Following the prescribed diet and exercise regimen is crucial as lifestyle habits significantly impact diabetes management.
Common side effects of Istamet XR Tablet include diarrhea, nausea, vomiting, upset stomach, headache, sore throat, and the possibility of low blood sugar levels (hypoglycemia), especially when used alongside other diabetes medications. Patients should be aware of hypoglycemia symptoms, such as dizziness, sweating, palpitations, and hunger, and be prepared to manage them promptly. Individuals with kidney, liver, or heart conditions, pancreatic issues, or alcohol consumption habits need to inform their doctor before starting this medication. Pregnant or breastfeeding women should consult their healthcare provider as well.
Istamet XR Tablet is a valuable therapeutic option for managing blood glucose levels in patients with type 2 diabetes mellitus. It comprises Sitagliptin and Metformin, which belong to different classes of anti-diabetic medications. Sitagliptin works by increasing substances that lower blood sugar levels, while Metformin reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin.
To prevent an upset stomach, Istamet XR Tablet should be taken with food at the same time each day for consistency. Dosage adjustments may be necessary based on the individual's response to treatment. Hypoglycemia is a common side effect, so it is crucial to maintain a regular meal schedule and have quick sugar sources on hand to manage low blood sugar events. Abrupt discontinuation of Istamet XR Tablet can lead to elevated blood sugar levels and complications such as retinopathy, nephropathy, and neuropathy, emphasizing the importance of medical supervision throughout treatment.
Benefits
Istamet XR Tablet offers various benefits in the treatment of Type 2 diabetes mellitus. This medication is a combination of two powerful medicines that work together to effectively lower blood glucose levels. Managing diabetes and keeping blood glucose levels under control are crucial in preventing serious complications associated with the condition. By consistently taking Istamet XR Tablet as prescribed, you can reduce the risk of complications such as kidney damage, eye damage, nerve problems, and even loss of limbs.
Furthermore, maintaining proper control of blood glucose levels with this medication can also help lower the risk of heart disease and stroke. By following a recommended diet and exercise regimen, in addition to regular use of this medicine, individuals can significantly improve their overall quality of life. It is important to adhere to the prescribed treatment plan and continue using Istamet XR Tablet as directed to safeguard your future health and well-being. Embracing a holistic approach to diabetes management with this medication can support you in living a normal, healthy life.
How to use the Istamet XR Tablet
To use Istamet XR Tablet, follow your doctor's instructions on the dose and duration. Swallow the tablet whole with a glass of water, preferably after eating a meal. Do not chew, crush, or break the tablet. Your doctor will determine the appropriate dosage and course of treatment based on factors like your age, weight, and medical condition. It is important to take this medicine exactly as prescribed by your doctor and not to stop unless advised to do so. If you have any questions or concerns about how to use Istamet XR Tablet, consult your healthcare provider for clarification.
Uses of Istamet XR Tablet
Istamet XR Tablet is commonly used for the treatment of Type 2 diabetes mellitus. It is specifically designed to help manage this condition effectively. By taking this tablet as prescribed, individuals with Type 2 diabetes mellitus can better control their blood sugar levels and improve their overall health. This medication plays a vital role in the treatment plan for those living with Type 2 diabetes mellitus, assisting them in maintaining a healthy and balanced lifestyle.
What conditions Istamet XR Tablet treats?
Istamet XR Tablet is used to treat Type 2 diabetes mellitus. It consists of two medications that work together to lower blood sugar levels, which is important for managing diabetes. By controlling blood sugar levels, the risk of serious complications such as kidney damage, eye damage, nerve problems, and heart disease is decreased. Taking this medication regularly, along with a healthy diet and exercise, supports a normal and healthy life. It is crucial to continue using this medicine as prescribed to protect your future health.
Should you consult a doctor?
It is important to seek medical attention if you experience certain conditions while taking Istamet XR Tablet. Consult a doctor if you have severe, uncontrollable diabetes, nausea, vomiting, diarrhea, rapid weight loss, lactic acidosis, ketoacidosis, dehydration, severe systemic infection, shock, circulation issues, breathing problems, are an alcoholic, or have upcoming X-rays. Before starting this medication, disclose to your doctor if you have a history of pancreatitis, alcohol dependence, high blood lipids, type I diabetes, scheduled for major surgery, fasting, malnourished, extreme muscle exercises, or vitamin B12 deficiency. Promptly seek medical advice to prevent any potential complications.
Side effects of Istamet XR Tablet
When taking Istamet XR Tablet, some common side effects you may experience include decreased appetite, vomiting, upper respiratory tract infection, hypoglycemia (low blood glucose level), abdominal bloating, nausea, and diarrhea. These side effects typically fade as your body gets used to the medication. However, if these symptoms persist or if you are concerned, it is essential to consult your doctor.
Other common side effects you may encounter are drowsiness, dizziness, dry mouth, headache, and skin itching. If you notice any severe reactions, it is important to stop taking the tablet and seek immediate medical attention. Serious allergic reactions like hives, swelling of the face, lips, tongue, or throat causing breathing difficulties, or severe blistering of the skin could occur. In rare cases, signs of pancreatitis such as severe stomach pain or signs of lactic acidosis like cold extremities, irregular heartbeat, unusual muscle pain, and difficulty breathing may develop. Additionally, swelling of the hands and legs, upper respiratory infections, joint pain, and a metallic taste in the mouth are potential side effects that require prompt medical intervention. If you experience any of these severe symptoms, it is crucial to consult your doctor without delay.
Safety advice

liver
Istamet XR Tablet may not be safe for individuals with liver disease and it is advised to avoid using it in such cases. It is crucial to consult with your doctor before considering this medication to ensure it is suitable for your liver health.

kidney
Istamet XR Tablet should be used with caution if you have kidney disease. Your doctor may need to adjust the dose. Avoid using if you have severe kidney disease. Regular kidney function tests are recommended during treatment.

alcohol
It is not safe to drink alcohol while taking Istamet XR Tablet.

driving
"Driving caution Your driving may be affected by high or low blood sugar. Avoid driving if experiencing these symptoms."

pregnancy
Istamet XR Tablet should be avoided during pregnancy as it may be unsafe. Animal studies indicate possible harm to the developing baby. Consult your doctor for weighing the benefits and risks before using this medication.

breastfeeding
Caution Istamet XR Tablet is likely unsafe during breastfeeding. Limited data indicates it may pass into breastmilk and harm the baby.
Age above 75(Geriatrics)
Istamet XR Tablet should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
Age below 6 months(Pediatrics)
Istamet XR Tablet is not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.
Consumption warning before consuming Istamet XR Tablet
Before consuming Istamet XR Tablet, it is essential to consider some important warnings. This medicine is a combination of two drugs that help regulate high blood sugar in individuals with type 2 diabetes. It aids in preventing severe complications like kidney damage and vision problems, as well as lowering the risk of heart issues. It is advisable to take Istamet XR Tablet consistently at the same time each day, following your doctor's instructions. Not stopping the medication abruptly is crucial unless advised by your healthcare provider.
This medication may result in common side effects such as diarrhea, nausea, upset stomach, headaches, and sore throat. Furthermore, there is a risk of experiencing low blood sugar levels (hypoglycemia), especially if taking other diabetes medications concurrently. Always be aware of the symptoms and how to manage hypoglycemia. Istamet XR Tablet may not be suitable for everyone. Inform your doctor about any kidney, liver, heart, or pancreatic issues, alcohol consumption habits, and pregnancy or breastfeeding status. Be cautious of potential interactions with other medications and minimize alcohol intake to maintain stable blood glucose levels. Regular monitoring of kidney function and blood sugar levels is necessary during treatment.
What if you forgot to take Istamet XR Tablet?
If you forget to take a dose of Istamet XR Tablet, try to take it as soon as you remember. But if it's nearly time for your next scheduled dose, it's best to skip the missed one and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one. Stay consistent with your doses to ensure the medication works effectively.
What happens if you take overdose of Istamet XR Tablet?
In case of an accidental overdose of Istamet XR Tablet, it is crucial to seek prompt medical attention. Symptoms of an overdose may include feeling cold or uncomfortable, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps, and fast breathing. Consulting a doctor or visiting the nearest hospital is essential to address any potential complications that may arise from taking more than the prescribed dose of the medication.
Related lab tests
Related Lab Tests for monitoring the effectiveness of Istamet XR Tablet may include:
1. Blood Glucose - Fasting Blood: This test measures the glucose levels in the blood after a period of fasting and is important in managing diabetes.
2. Blood Glucose - Postprandial Blood: This test measures the glucose levels in the blood after consuming a meal, providing insight into how the body processes sugar post meals.
3. Glycosylated Hemoglobin (HbA1C): This test reflects the average blood sugar levels over the past 2-3 months and is a key indicator of long-term blood sugar control in individuals with diabetes.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | ANTI DIABETIC |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹159
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024