Neotrexate Injection
By Neotrexate
Rx
2ml Injection in a Vial

Composition
Methotrexate(50mg)

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd
Dr. Annie Besant Road, Mumbai - 400 030

Expires on or after
September, 2025
About Neotrexate Injection
Neotrexate Injection is a medication prescribed for the treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It can be used in combination with other medicines as part of a comprehensive therapy plan. This injection should always be administered under the careful supervision of a healthcare professional and should never be self-administered. Your dosing schedule and the amount of Neotrexate Injection you receive will be determined by your doctor based on your specific condition and may need adjustments over time. It is crucial to follow your doctor's instructions precisely to avoid serious side effects.
It may take some time, possibly weeks or months, before you start noticing the benefits of Neotrexate Injection. Do not discontinue the treatment unless advised by your doctor, as stopping abruptly can be harmful. Alcohol consumption should be avoided while on this medication to minimize the risk of liver damage. Like any medication, Neotrexate Injection can cause side effects, including nausea, vomiting, loss of appetite, tiredness, and mouth sores. These side effects may be managed with folic acid supplementation. If these side effects persist or worsen, inform your doctor promptly.
Neotrexate Injection is a potent medication, and some individuals may experience severe side effects while using it. It can lower your body's ability to fight infections and may lead to complications with your blood, liver, or kidneys. Your healthcare provider will likely recommend regular blood tests to monitor for any potential issues. Before starting Neotrexate Injection, inform your doctor if you have stomach, liver, or kidney problems, or if you are taking any medications for infections. It is important to disclose all the medications you are currently using, as there could be interactions with Neotrexate Injection.
Due to the potential risks, Neotrexate Injection is not recommended during pregnancy or while breastfeeding, as it may harm the baby. It is advised to use effective contraception methods during the treatment period and for some time after stopping the medication. Your doctor may conduct various tests such as blood tests, X-rays, and physical examinations before and during your Neotrexate Injection treatment to ensure your safety and monitor your progress effectively.
Benefits
Neotrexate Injection is a powerful medication that falls under the category of antimetabolites, known for its cytotoxic properties. One of the key benefits of this drug is its effectiveness in slowing down the growth of cancer cells within the body. It is widely utilized in the treatment of various types of cancers, including acute leukemias, non-Hodgkin’s lymphoma, and solid tumors present in areas such as the breast, lung, bladder, head and neck, as well as cervical, ovarian, and testicular cancers. The flexibility of Neotrexate Injection allows it to be administered either as a standalone treatment or in conjunction with other medications, providing a versatile approach to cancer therapy.
It is crucial for patients to have open discussions with their healthcare provider regarding the potential risks and benefits associated with Neotrexate Injection due to its potency and high toxicity levels. To optimize the outcomes of the treatment, individuals are advised to abstain from consuming alcoholic beverages during the medication course. Additionally, staying well-hydrated by drinking ample water is recommended to support the body throughout the treatment process. Overall, the benefits of Neotrexate Injection lie in its ability to target and combat cancer cells effectively, offering hope and valuable treatment options for patients battling various forms of cancer.
How to use the Neotrexate Injection
To use Neotrexate Injection, it is important to follow the instructions provided by your doctor or nurse. This medication should not be self-administered. Your healthcare provider will administer the injection to you in the appropriate dosage and frequency. It is crucial to avoid attempting to administer this medication yourself, as it can be harmful if not done correctly. By allowing your doctor or nurse to give you the injection, you can ensure that you are receiving the proper care and dosage tailored to your specific needs. Always consult your healthcare provider if you have any questions or concerns about the use of Neotrexate Injection.
Uses of Neotrexate Injection
Neotrexate Injection is utilized in the treatment of cancer.
What conditions Neotrexate Injection treats?
Neotrexate Injection is used to treat various types of cancer in different body parts like breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is important to follow the dosage instructions given by your doctor as taking it incorrectly can lead to serious side effects. Common side effects include nausea, vomiting, fatigue, and decreased white blood cell count. This medicine can weaken your immune system and impact your liver, kidneys, and blood, so regular monitoring is necessary. It is not recommended during pregnancy or breastfeeding. Discuss all medications and any existing health conditions with your healthcare provider before starting this treatment.
Should you consult a doctor?
Seek medical attention if you experience persistent or worsening side effects such as nausea, vomiting, loss of appetite, abdominal pain, tiredness, mouth sores, or decreased white blood cells while taking Neotrexate Injection. Inform your doctor if these side effects do not improve or become severe. Additionally, consult your healthcare provider if you have stomach, liver, or kidney issues, or are taking medications for infections. It is crucial to follow your doctor's instructions carefully and not stop the treatment unless advised. Regular blood tests and monitoring will be conducted to check for potential complications. Refrain from consuming alcohol as it can increase the risk of liver damage. If you are pregnant, breastfeeding, or planning to conceive, discuss the risks and precautions with your healthcare team. Your doctor may schedule various tests before and during the treatment to ensure your safety and well-being.
Side effects of Neotrexate Injection
When taking Neotrexate Injection, some individuals may experience certain side effects. It's important to note that most of these side effects usually fade away as your body gets used to the medicine. However, if they persist or cause concern, it's recommended to consult your doctor.
Common side effects of Neotrexate Injection may include abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, mouth sores, and decreased white blood cell count. If you notice any of these side effects and they persist or become bothersome, seek medical advice for proper evaluation and management. Monitor your symptoms closely and communicate any concerns with your healthcare provider to ensure your well-being while using Neotrexate Injection.
Safety advice

liver
When using Neotrexate Injection, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment, so consulting your doctor is essential. It is advised not to use Neotrexate Injection in cases of severe liver disease.

kidney
Neotrexate Injection requires caution in patients with kidney disease. Dose adjustment may be necessary. Regular monitoring of kidney function test is recommended during treatment.

alcohol
When taking Neotrexate Injection, be cautious when drinking alcohol. Consult your doctor for guidance.

driving
When using Neotrexate Injection, beware of decreased alertness, vision changes, and drowsiness. Avoid driving if experiencing these effects.

pregnancy
Neotrexate Injection is not safe to use during pregnancy. Studies have shown harmful effects on developing babies. Seek advice from your doctor.

breastfeeding
Neotrexate Injection should not be used while breastfeeding as it may harm the baby. It is advised to avoid breastfeeding while on this medication.
Consumption warning before consuming Neotrexate Injection
Before consuming Neotrexate Injection, it is crucial to note the following important information for your safety and well-being. This medication is primarily used to treat cancer in various areas of the body like the breasts, head, neck, lungs, blood, bone, lymph, and uterus, often as part of combination therapy under the supervision of a healthcare professional. It is vital not to self-administer this injection as the dosage and frequency are determined by your doctor based on your specific condition and may change over time. Taking Neotrexate Injection incorrectly or in excess can result in severe side effects, so always follow your doctor's instructions precisely.
Common side effects of this medication include nausea, vomiting, loss of appetite, abdominal pain, fatigue, mouth sores, and reduced white blood cell count. Your doctor may recommend taking folic acid to alleviate some of these symptoms. Remember that Neotrexate Injection is potent, and some individuals may experience significant side effects affecting their ability to fight infections and impacting their blood, liver, or kidneys. Regular blood tests are essential to monitor for potential issues. Prior to starting this treatment, inform your doctor of any stomach, liver, or kidney problems, as well as any other medications you are taking. Avoid consuming alcohol while on this medication as it can increase the risk of liver damage. Additionally, it is not advisable to use this medication during pregnancy or breastfeeding, as it may harm the baby. It is advisable to engage in contraception to avoid pregnancy during and after the treatment. Be prepared for various tests such as blood tests and X-rays before and during the treatment to ensure your well-being.
What if you forgot to take Neotrexate Injection?
If you forgot to take your scheduled dose of Neotrexate Injection, it's important to reach out to your doctor for guidance. It is recommended to consult your healthcare provider immediately regarding a missed dose of Neotrexate Injection. Your doctor will be able to provide you with specific instructions on how to proceed based on your individual situation.
Additional Information
Habit Forming | No |
Chemical Class | Glutamic Acid Derivatives |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolite- Methotrexate |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 01-Oct-2024