Metifex SI 250mg/125mg Injection
By Metifex SI
Rx
1 Injection in a Vial

Composition
Ceftriaxone(250mg) + Sulbactam(125mg)

Manufacturer - Zee Laboratories
Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)

Expires on or after
August, 2025
About Metifex SI 250mg/125mg Injection
Metifex SI 250mg/125mg Injection is a combination medication used to treat various types of bacterial infections. It works by fighting against the microorganisms to prevent their growth and further spread of the infection. It is important to note that this medication should only be administered under the supervision of a healthcare professional. It is essential not to miss any scheduled appointments for taking this medicine, and the full course of treatment should be completed even if the patient starts feeling better. Abruptly stopping the treatment may compromise the effectiveness of the medicine.
Some common side effects of Metifex SI 250mg/125mg Injection include nausea, vomiting, diarrhea, and indigestion. If any of these side effects worsen, it is crucial to consult a doctor promptly. In case of experiencing any allergic reactions such as rashes, itching, swelling, or shortness of breath, immediate medical assistance should be sought.
Before starting this medication, it is important to inform your doctor about any other medicines you are taking for existing health conditions. Pregnant or breastfeeding women should consult with their healthcare provider before taking Metifex SI 250mg/125mg Injection. It is advisable to avoid consuming alcohol while on this medication as it can lead to excessive drowsiness. Although this medicine generally does not impair the ability to drive, it is recommended not to operate vehicles if it causes drowsiness or dizziness. Adequate rest, a healthy diet, and staying hydrated are essential for a speedier recovery process. Additionally, the doctor may request laboratory and diagnostic tests to monitor the effects of the medicine on the body.
Benefits
Metifex SI 250mg/125mg Injection offers multiple benefits in the treatment of bacterial infections. This medication combines the effectiveness of two powerful ingredients, Ceftriaxone and Sulbactum, to combat the bacteria responsible for causing infections. Ceftriaxone functions by halting the growth of bacteria, while Sulbactam works to decrease resistance and enhance the activity of Ceftriaxone against bacteria.
The synergistic action of these two medicines within Metifex SI 250mg/125mg Injection allows for effective eradication of various bacterial infections affecting areas such as the ear, sinus, throat, lung, urinary tract, skin, and soft tissues. Patients can experience noticeable improvement in their condition within just a few days of starting the treatment. It is crucial to follow the prescribed course of Metifex SI 250mg/125mg Injection even after feeling better to ensure complete elimination of the bacteria, thereby preventing the development of resistance.
In summary, Metifex SI 250mg/125mg Injection stands out as a reliable and potent treatment option for bacterial infections, offering quick relief and ensuring thorough eradication of bacterial pathogens to support overall recovery and wellbeing.
How to use the Metifex SI 250mg/125mg Injection
When using Metifex SI 250mg/125mg Injection, it is important to remember that only a doctor or nurse should administer this medicine to you. It should be given either intravenously or intramuscularly. Do not try to administer it yourself. Your doctor will determine the appropriate dosage based on factors such as your age, body weight, and the seriousness of the infection you are dealing with. Trust your healthcare provider to give you the right dose in a safe and effective manner. Remember, your health is important, so always follow your doctor's instructions when using Metifex SI 250mg/125mg Injection.
Uses of Metifex SI 250mg/125mg Injection
Metifex SI 250mg/125mg Injection is commonly used for treating various bacterial infections. This antibiotic injection is effective in managing urinary tract infections, lower respiratory tract infections, bacteremia, septicaemia, meningitis, abdominal infections, and infections caused by pseudomonas species. It is important to note that Metifex SI 250mg/125mg Injection should only be used as prescribed by a healthcare professional to ensure proper treatment of the specific bacterial infection present.
What conditions Metifex SI 250mg/125mg Injection treats?
Metifex SI 250mg/125mg Injection is used to treat various bacterial infections. It contains two medicines, Ceftriaxone and Sulbactum, which work together to kill the bacteria causing the infections. This medication can be effective for treating infections in the ear, sinus, throat, lung, urinary tract, skin, and soft tissues. It is important to complete the full course of treatment to ensure all bacteria are eliminated and to prevent the development of resistance. Adhere to scheduled appointments and consult your doctor if you experience any side effects or allergic reactions.
Should you consult a doctor?
Seek medical attention immediately if you experience any signs of gastrointestinal disease (colitis) after receiving Metifex SI 250mg/125mg Injection. Inform your doctor before treatment if you have haemolytic anaemia, which can cause symptoms like pale yellow skin, weakness, or breathlessness. Additionally, ensure to disclose if you are on a low sodium diet.
Side effects of Metifex SI 250mg/125mg Injection
When using Metifex SI 250mg/125mg Injection, some potential side effects may occur as your body adapts to the medication. Common side effects include increased white blood cell count (eosinophils), decreased white blood cell count (lymphocytes), and low blood platelets. You may also experience rash, diarrhea, increased liver enzymes, and injection site reactions like pain, swelling, and redness. Other possible side effects include anaemia, nausea, vomiting, itching sensation (pruritus), increased blood creatinine levels, fungal infections, and decreased white blood cells (granulocytopenia). Blood clots, pain along the vein, fever, abnormalities in white blood cells and platelets, and diarrhea may also occur. Thrombocytosis, leukopenia, headache, dizziness, changes in liver function, bronchospasm, blood in urine (haematuria), glucose in urine (glycosuria), chills, inflammation of the colon, lumpy rash (hives), itching, swelling, and fluid build-up (oedema) are possible side effects as well. Contact your doctor if you experience sudden swelling of the face, throat, lips, or mouth; a severe rash with blisters or peeling skin; widespread rash with high body temperature; liver enzyme elevations; blood abnormalities; enlarged lymph nodes; or symptoms of Jarisch-Herxheimer reaction such as fever, chills, headache, muscle pain, and skin rash.
Safety advice

liver
When using Metifex SI 250mg/125mg Injection, it is important to be cautious if you have severe liver disease. In such cases, your doctor may need to adjust the dosage of the injection. It is crucial to consult your doctor before using this medication if you have severe liver issues. However, dose adjustment of Metifex SI 250mg/125mg Injection is generally not recommended for patients with mild to moderate liver disease. Always follow your doctor's guidance regarding the proper use of this injection, especially if you have any liver concerns.

kidney
Consult with your doctor for proper guidance before using Metifex SI 250mg/125mg Injection.

alcohol
When taking Metifex SI 250mg/125mg Injection, it is safe to consume alcohol as it does not lead to any harmful effects.

driving
Metifex SI 250mg/125mg Injection can reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these effects.

pregnancy
Metifex SI 250mg/125mg Injection is generally considered safe during pregnancy with low risks based on animal studies. Limited human studies available.

breastfeeding
During breastfeeding, caution is advised when using Metifex SI 250mg/125mg Injection. It is recommended to pause breastfeeding until the treatment of the mother is finished and the drug is cleared from her system.
Age above 75(Geriatrics)
Metifex SI 250mg/125mg Injection should be used with caution in elderly patients. Consult your doctor before receiving this medicine.
Age below 6 months(Pediatrics)
Your doctor will administer the right dose depends on your child’s age, body weight and severity of the infection. Consult your doctor before receiving Metifex SI 250mg/125mg Injection.
Consumption warning before consuming Metifex SI 250mg/125mg Injection
Metifex SI 250mg/125mg Injection is a powerful combination medication used to treat bacterial infections. It should only be given by a healthcare professional to ensure safe and effective treatment. Attend all scheduled appointments and complete the full course of treatment even if symptoms improve to prevent the infection from returning. Abruptly stopping the treatment can reduce its effectiveness.
Common side effects like nausea, vomiting, diarrhea, and indigestion may occur. Inform your doctor if these side effects worsen. Seek immediate medical attention if you experience signs of an allergic reaction such as rashes, itching, swelling, or breathing difficulties.
Before using Metifex SI 250mg/125mg Injection, disclose all medications being taken and consult your doctor, especially if pregnant or breastfeeding. Avoid alcohol consumption as it can intensify drowsiness. While it typically does not impair driving ability, refrain from driving if feeling excessively tired or dizzy. Adequate rest, healthy eating, and staying hydrated aid in recovery. Follow-up tests may be required to monitor your body's response to the medication.
What if you forgot to take Metifex SI 250mg/125mg Injection?
If you forget to take a dosage of Metifex SI 250mg/125mg Injection, it is important to seek guidance from your doctor. It is crucial to consult with your healthcare provider for advice on the best course of action in this situation. Remember that missing a dose can affect the effectiveness of the medication, so it is essential to address any missed doses promptly.
What happens if you take overdose of Metifex SI 250mg/125mg Injection?
In the case of Metifex SI 250mg/125mg Injection, the likelihood of an overdose is minimal due to the controlled administration by healthcare professionals such as doctors or nurses. If by any chance you notice unusual side effects following the administration of this injection, it is crucial to seek immediate medical consultation from your doctor. This ensures that any unexpected reactions or symptoms are promptly addressed and managed effectively.
Related lab tests
Related Lab Tests:
When using Metifex SI 250mg/125mg Injection, it is important to monitor certain lab tests to ensure the medication is working effectively and not causing any harmful effects on the body. One important test to consider is the Complete Blood Count (CBC). The CBC provides information on various components of the blood, including red blood cells, white blood cells, and platelets. This test can help detect any abnormalities such as infections or anemia that may require further medical attention.
Another important lab test to consider is the Peripheral Smear Examination. This test involves the microscopic examination of a sample of blood to evaluate the size, shape, and number of different blood cells. It can provide valuable information about various blood disorders and conditions, such as anemia, leukemia, and infections. Monitoring the results of the Peripheral Smear Examination can help healthcare providers adjust treatment plans and ensure the patient's overall health and well-being.
In summary, when administering Metifex SI 250mg/125mg Injection, it is recommended to regularly monitor a Complete Blood Count (CBC) and a Peripheral Smear Examination to assess the impact of the medication on the body and detect any potential complications.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | ANTI INFECTIVES |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 18-Nov-2024