Grafnos 0.5 Capsule

By Grafnos

Rx

10 Capsule in a Strip

Composition icon

Composition

Tacrolimus(0.5mg)

Manufacturer - Akognos Life Sciences icon

Manufacturer - Akognos Life Sciences

Corporate & Registered Office, Akognos Life Sciences Pvt. Ltd., Manish Plaza, Third Floor, Plot No. 25, Sector-20 , Dwarka, New Delhi -110075

Expires on or after icon

Expires on or after

January, 2027

About Grafnos 0.5 Capsule

Grafnos 0.5 Capsule 10's is classified as an immunosuppressant drug, designed to be used in combination with other medications to safeguard newly transplanted organs – such as liver, kidney, or heart – from rejection by the body's immune system. The active ingredient in Grafnos 0.5 Capsule 10's is Tacrolimus, which operates by suppressing the activity of T and B lymphocytes, important cells in the immune system responsible for defending against foreign invaders. By inhibiting these immune responses, Grafnos 0.5 Capsule 10's helps in preventing organ rejection following transplantation and supports the body in accepting the new organ.

When taking Grafnos 0.5 Capsule 10's, it is crucial to adhere strictly to the prescribed dosage and schedule provided by your healthcare provider. The amount and frequency of intake will vary based on the type of transplant received, individual body weight, and concurrent medications. To ensure efficacy, it is recommended to consume this medication on an empty stomach, at least 1 hour before or 2 hours after eating. Consistency in taking Grafnos 0.5 Capsule 10's is key to maximizing its benefits, even if you are feeling well, as discontinuing its use could heighten the risk of organ rejection.

Despite its benefits, Grafnos 0.5 Capsule 10's may come with potential side effects that require attention. These include the possibility of developing or exacerbating conditions such as diabetes, kidney problems, tremors, infections, hypertension, and insomnia. It is advised to seek immediate medical attention for serious side effects, and to communicate any persistent or worsening symptoms with your healthcare provider. Notably, the drug compromises the immune system, making individuals more susceptible to infections compared to normal conditions.

Prior to initiating treatment with Grafnos 0.5 Capsule 10's, it is vital to inform your doctor of any existing medical conditions, particularly related to kidney, liver, or heart health, as well as diabetes and hypertension. Disclose all other medications being taken, especially those for infections, pain, or arthritis, as interactions may occur. Additionally, individuals using Grafnos 0.5 Capsule 10's, both males and females, should employ effective birth control methods to prevent pregnancy, and unless absolutely necessary, the drug is not generally recommended during pregnancy or breastfeeding. Regular medical monitoring and blood pressure checks are necessary during treatment to track progress and ensure safety.

Lastly, caution should be exercised to limit exposure to sunlight and UV light while on Grafnos 0.5 Capsule 10's, as immunosuppressants can heighten the risk of skin cancer. If allergic to Tacrolimus or any other medications, pregnant, breastfeeding, or experiencing persistent side effects, consultations with a healthcare professional are advised. Avoiding alcohol consumption while taking Grafnos 0.5 Capsule 10's is recommended, and driving or operating machinery should only be done when fully alert due to potential vision problems or nervous disturbances. Prior notification to the doctor is essential before undergoing vaccinations while on Grafnos 0.5 Capsule 10's, given the increased susceptibility to infections or skin cancer associated with lowered immune defense.


Benefits

Grafnos 0.5 Capsule is beneficial in preventing organ rejection in transplant patients. When a person undergoes an organ transplant, their immune system may recognize the new organ as a threat and attack it. Grafnos 0.5 Capsule, which is an immunosuppressant medication, works by weakening the immune response that normally fights infections. By doing this, it reduces the likelihood of the body rejecting the transplanted organ. This medicine is often used in conjunction with other medications to increase the success rate of the transplant operation. It contains Tacrolimus, which specifically targets and suppresses the activity of T and B lymphocytes - important cells in the immune system that typically defend the body against foreign cells and infection. By inhibiting these cells, Grafnos 0.5 Capsule helps the body accept the new organ and lowers the risk of rejection in transplant patients. It is crucial to follow the doctor's instructions and continue taking the medication as prescribed to ensure the best possible outcome of the transplant.


How to use the Grafnos 0.5 Capsule

To use Grafnos 0.5 Capsule, follow the directions given by your doctor carefully. Take this medication on an empty stomach. If you are instructed to take the capsule, swallow it whole with water, and do not crush, break, or chew it. In case you are using the granules, mix them with water to create an oral suspension. Consume the suspension immediately after preparation and do not store it for future use. Remember that the dosage and duration of taking this medicine should be as per your doctor's guidance to ensure maximum benefits and safety. If you have any questions about how to use Grafnos 0.5 Capsule, do not hesitate to consult your healthcare provider for further clarification and assistance.


Uses of Grafnos 0.5 Capsule

Grafnos 0.5 Capsule is commonly used to prevent organ rejection in patients who have undergone a transplant. It is specifically known for its ability to prevent the rejection of transplanted organs, helping the body accept and adapt to the new organ. By taking this medication as prescribed, transplant patients can enhance the success of their transplant procedure and improve their overall health.


What conditions Grafnos 0.5 Capsule treats?

Grafnos 0.5 Capsule is used to prevent organ rejection, which happens when the body's immune system sees a transplanted organ as foreign and attacks it. Organ rejection can occur quickly (hyperacute), within months (acute), or after a year (chronic). Symptoms vary depending on the type of transplant. If you notice pain, fever, or feel unwell, seek medical help promptly.


Should you consult a doctor?

It is important to seek medical attention if you experience any serious side effects while taking Grafnos 0.5 Capsule. These include symptoms like increased blood glucose levels, kidney damage, insomnia, tremors, high blood pressure, and infections. These conditions require urgent medical attention and should not be ignored. Additionally, if you are concerned about persistent side effects or notice that they are getting worse over time, it is advised to consult your doctor. It is crucial to be proactive in addressing any health concerns that may arise while using Grafnos 0.5 Capsule to ensure your well-being and the effectiveness of your treatment. Regular monitoring by your healthcare provider is essential to manage any potential risks associated with this medication.


Side effects of Grafnos 0.5 Capsule

When taking Grafnos 0.5 Capsule , some side effects may occur as your body gets used to the medication. It is common for these side effects to go away on their own without medical treatment. However, if any of the following side effects persist or concern you, it is important to consult your doctor promptly. Possible side effects include increased glucose levels in the blood, kidney damage, insomnia (difficulty sleeping), tremors, high blood pressure, and the risk of infection. Other potential side effects may include nausea, diarrhea, headache, kidney problems, constipation, fever, and elevated blood pressure. If you experience any of these side effects and they persist or become bothersome, seek medical advice for proper evaluation and guidance.


Safety advice

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liver

When considering Grafnos 0.5 Capsule, it is important to be cautious if you have liver disease. Patients with liver conditions may require adjustment of the Grafnos 0.5 Capsule dosage. For individuals with liver diseases or conditions, it is strongly recommended to consult with a healthcare provider before initiating the use of Grafnos 0.5 Capsule.

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kidney

Grafnos 0.5 Capsule requires caution in kidney disease patients. Adjusting the dose may be necessary. Consult your doctor, especially if you have kidney conditions, before using Grafnos 0.5 Capsule.

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alcohol

To ensure safety while taking Grafnos 0.5 Capsule, it is important to avoid alcohol consumption. Mixing alcohol with this medication can lead to increased risk of adverse effects. It is advisable to consult your doctor before drinking alcohol while using Grafnos 0.5 Capsule.

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driving

Grafnos 0.5 Capsule can reduce alertness, impact vision, and induce drowsiness or dizziness. Avoid driving if you experience these effects. Vision issues or nervous disturbances may occur in some individuals, so refrain from driving if such symptoms arise post-taking Tacrol 0.5 mg Capsule 10's.

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pregnancy

Grafnos 0.5 Capsule may not be safe during pregnancy. Animal studies suggest potential harm to the developing baby. Consult your doctor for a thorough evaluation of benefits and risks before using this medication. If pregnant, be aware of possible kidney or neonatal hyperkalemia risks. Utilize effective contraception while taking Grafnos 0.5 Capsule.

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breastfeeding

Grafnos 0.5 Capsule may not be safe for breastfeeding as it can pass into breastmilk, potentially harming the baby. Inform your doctor if you are breastfeeding before taking this medication. It is advisable to avoid breastfeeding while using Grafnos 0.5 Capsule.


Consumption warning before consuming Grafnos 0.5 Capsule

Before taking Grafnos 0.5 Capsule , inform your doctor if you have allergies to Tacrolimus or other medicines. If you are pregnant or breastfeeding, consult your doctor before using this medication. It is recommended to avoid alcohol while taking Grafnos 0.5 Capsule . Be cautious when driving, as this medication can cause vision problems or nervous disturbances in some individuals. Notify your doctor if you are planning to get vaccinated while using Grafnos 0.5 Capsule . This medication may increase the risk of infections or skin cancer due to its effect on the immune system; therefore, wear protective clothing and sunscreen when going outside. Prepare the oral suspension using glass or metal materials to avoid granule adherence commonly experienced with plastic (PVC) containers. In case of accidental skin or eye contact with the granules or prepared oral suspension, wash the area thoroughly with soap and water or rinse with plain water, respectively.


What if you forgot to take Grafnos 0.5 Capsule?

If you forget to take a dose of Grafnos 0.5 Capsule, take it as soon as you remember. But if it's almost time for your next dose, just skip the missed one and continue with your usual dosing schedule. It's important not to take a double dose to make up for the missed one. Stick to your prescribed regimen to ensure the best outcomes from your medication.


Additional Information

Habit FormingNo
Chemical ClassMacrolide Lactams
Therapeutic Class-
Action ClassImmunosuppressant- Calcineurin inhibitors

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Preeti Kumar

MBBS, DGO - Obstetrics and Gynaecology, DNB - Obstetrics and Gynaecology

Last update on 01-Oct-2024