Gemfrac Injection

By Gemfrac

Rx

2ml Injection in a Pre-filled pen

Composition icon

Composition

Teriparatide(0.250mg/ml)

Manufacturer - Alkem Laboratories Ltd icon

Manufacturer - Alkem Laboratories Ltd

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after icon

Expires on or after

August, 2025

About Gemfrac Injection

Gemfrac Injection is a manufactured form of parathyroid hormone utilized to treat severe osteoporosis in men and postmenopausal women at a high risk of fractures. This medication functions by encouraging the formation of new bone, enhancing bone density, and reducing the likelihood of spinal fractures. To ensure maximum benefits, Gemfrac Injection should be administered under the skin or by a healthcare professional consistently at the same time each day. Typically, it is advised to be taken for a maximum of 2 years, following the doctor's recommendations and completing the prescribed course even if symptoms improve. Storage instructions specify that Gemfrac Injection should be kept refrigerated at a temperature between 2°C to 8°C.

Common side effects that may occur with Gemfrac Injection include joint pain, reactions at the injection site like pain, swelling, and redness, as well as leg cramps. It is recommended to consult with a healthcare provider if any of these side effects persist or pose concerns. Prior to commencing treatment with Gemfrac Injection, individuals with kidney stones or other kidney complications should inform their doctor, as the medication can impact calcium levels in the blood or urine. Pregnant and breastfeeding women must also consult their healthcare provider before initiating treatment. Doctors may suggest a bone scan to monitor treatment progress effectively.

Belonging to the class of medications labeled as anabolic agents that promote bone formation, Gemfrac 600 MCG Injection 1's is designed for the prevention and treatment of osteoporosis in adults to strengthen bones and decrease the risk of spine and hip fractures. Osteoporosis is a condition characterized by weakening and thinning bones, often exacerbated by factors such as aging, menopause, or prolonged use of corticosteroids. Gemfrac 600 MCG Injection 1's contains Teriparatide, a synthetic version of human parathyroid hormone that regulates calcium metabolism. The medication aids in building new bone, increasing bone strength and density, and reducing fracture risk by stimulating bone formation.

Administration of Gemfrac 600 MCG Injection 1's should be done by a healthcare professional and not self-administered. Possible side effects may include nausea, vomiting, joint pain, leg cramps, injection site reactions like swelling and redness, gastrointestinal issues, respiratory symptoms, and throat irritation. While most side effects tend to resolve over time without medical intervention, persistent symptoms warrant medical advice. Individuals should follow their doctor's prescribed treatment regimen for optimal effectiveness. Pregnant or breastfeeding individuals should seek medical guidance concerning the benefits and risks of Gemfrac 600 MCG Injection 1's. This medication is not suitable for individuals under 18 years old.

To maintain the integrity of Gemfrac 600 MCG Injection 1's, it is crucial to store it in a refrigerator within the specified temperature range of 2-8 degrees Celsius. Avoid freezing or storing in the freezer. Inform your doctor of your medication regimen before undergoing any laboratory tests, as Gemfrac 600 MCG Injection 1's could potentially influence the results. Be cautious of potential dizziness, lightheadedness, or fainting upon standing up quickly from a lying position, and take precautions to avoid such occurrences.


Benefits

Gemfrac Injection, containing Teriparatide, offers several benefits in the treatment of osteoporosis. It helps slow down the breakdown of bone in the body, thus maintaining bone density and reducing the risk of fractures. By stimulating bone formation and increasing bone strength and mass density, Gemfrac Injection effectively rebuilds bones, especially in individuals with weak bones after menopause. This synthetic form of the natural hormone parathyroid hormone (PTH) promotes new bone growth and decreases the risk of spine and hip fractures, enhancing overall bone health. Additionally, Gemfrac Injection is recommended for individuals with osteoporosis, including those with glucocorticoid-induced osteoporosis, to increase bone mass and prevent further bone loss. It is important to administer Gemfrac Injection under the supervision of a healthcare professional, as it should not be self-administered. In conjunction with the injection, adopting healthy habits such as regular weight-bearing exercise, calcium and Vitamin D-rich diet, and minimizing alcohol and tobacco consumption can further contribute to improving bone strength and reducing the likelihood of fractures. Supplementing with calcium and Vitamin D3 alongside Gemfrac Injection can also enhance its effectiveness in treating osteoporosis.


How to use the Gemfrac Injection

To use Gemfrac 600 MCG Injection, you will need a healthcare professional such as a doctor or nurse to administer it. It is important not to try to give yourself the injection. The healthcare professional will determine the correct dosage for you based on your specific medical condition. Gemfrac Injection should be administered as directed, usually in a healthcare setting such as a clinic or hospital. It is important to follow the instructions carefully and not to skip any doses. If you have any questions or concerns about how to use Gemfrac Injection, be sure to consult your healthcare provider for guidance. Remember, always rely on a healthcare professional for the proper administration of Gemfrac Injection.


Uses of Gemfrac Injection

Gemfrac Injection is primarily used in the treatment of osteoporosis, particularly postmenopausal osteoporosis. This injection is targeted at managing the weakening of bones that occurs after menopause. Postmenopausal osteoporosis is a condition where bones become fragile and are more prone to fractures due to decreased estrogen levels. Gemfrac Injection helps in this scenario by possibly increasing bone density and strength, reducing the risk of fractures in individuals affected by postmenopausal osteoporosis. It is a valuable option to consider for those seeking to improve bone health and reduce the complications associated with osteoporosis.


What conditions Gemfrac Injection treats?

Osteoporosis is a condition that causes bones to become thin and weak. It is more common as people age, especially after menopause or with long-term use of corticosteroid medications like prednisone. If left untreated, osteoporosis can lead to broken bones, which can occur during daily activities. Fractures commonly happen in the hip, spine, or wrist, leading to posture changes and restricted movement. Symptoms may not appear initially, making early treatment crucial to prevent complications.


Should you consult a doctor?

When taking Gemfrac Injection, it is important to seek medical attention if you experience persistent side effects such as joint pain, injection site reactions like pain, swelling, or redness, nausea, or leg cramps. If these side effects bother you or do not go away, consulting with your doctor is advisable. Additionally, informing your doctor beforehand if you have kidney stones, kidney problems, are pregnant, or breastfeeding is essential, as Gemfrac Injection can affect calcium levels and require monitoring. Furthermore, if there is any concern regarding the medicine or its effects, do not hesitate to reach out to your healthcare provider. Remember to follow the prescribed dosing regimen and store the medication as directed to ensure its effectiveness.


Side effects of Gemfrac Injection

Gemfrac Injection may cause certain side effects, although most of them do not typically require medical attention and tend to fade as your body gets used to the medication. However, it is recommended to consult your doctor if any of the following side effects persist or if you feel concerned. Common side effects of Gemfrac Injection can include joint pain, reactions at the injection site such as pain, swelling, and redness, nausea, leg cramps, vomiting, dizziness, fatigue, weakness, upset stomach, diarrhea, constipation, runny nose, cough, and throat irritation. If you experience any of these side effects and they are bothersome or persistent, it is advisable to seek medical advice.


Safety advice

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liver

When it comes to using Gemfrac Injection for patients with liver disease, it's crucial to be careful due to limited available information in this area. Dose adjustment may be necessary. If you have liver impairment or liver disease, it's essential to consult your doctor before using Gemfrac 600 MCG Injection 1's to ensure the appropriate caution is taken. Remember, your doctor is the best person to guide you based on your individual health situation.

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kidney

Gemfrac Injection requires caution in patients with kidney disease. Dose adjustment may be necessary, and it is not recommended for those with severe kidney disease. Inform your doctor about any kidney disorders for an accurate assessment of safety in prescribing Gemfrac Injection.

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alcohol

It is advised to be cautious when drinking alcohol with Gemfrac Injection. Avoid alcohol while taking Gemfrac 600 MCG Injection 1's to prevent increased drowsiness.

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driving

Caution should be taken when driving while using Gemfrac Injection, as it may reduce alertness, cause dizziness, fatigue, and blurred vision. Do not drive if you experience these symptoms to ensure safety on the road.

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pregnancy

Gemfrac Injection is not recommended for use during pregnancy. Animal studies have indicated potential harm to the developing baby. Consult your doctor before taking Gemfrac 600 MCG Injection 1's during pregnancy, as it is considered a category C drug with potential risks.

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breastfeeding

Information regarding the use of Gemfrac Injection during breastfeeding is not available. Please consult your doctor. It isn’t known if Gemfrac 600 MCG Injection 1's passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.


Consumption warning before consuming Gemfrac Injection

Before using Gemfrac 600 MCG Injection 1's, it's important to note some considerations. Avoid this injection if you have conditions like hypercalcemia, an overactive parathyroid gland, metastatic calcification, malabsorption syndrome, kidney stones, moderate renal impairment, Paget’s disease of bone, or a history of skeletal malignancies. Regular check-ups with your doctor are crucial to monitor the injection's effectiveness. Blood and urine tests may be necessary to detect any adverse effects, as Gemfrac 600 MCG Injection 1's can elevate calcium levels in your body. Be cautious if experiencing symptoms like nausea, vomiting, constipation, low energy, or muscle weakness, as they could indicate excess calcium in your system. Consult your doctor if you are pregnant or breastfeeding, as the benefits and risks need evaluation. Avoid giving this injection to children and only use it as prescribed. Prolonged use may increase cancer risk, so discuss any concerns with your doctor. Additionally, avoid alcohol consumption with this injection to prevent heightened drowsiness. Inform your doctor about your health status and medications before starting Gemfrac 600 MCG Injection 1's to mitigate potential side effects.


What if you forgot to take Gemfrac Injection?

If you miss a dose of Gemfrac Injection, you should try to take it as soon as you remember. However, if it is nearly time for your next scheduled dose, it's best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for the missed one.


Related lab tests

For individuals receiving Gemfrac Injection, it is important to monitor their calcium levels through regular lab tests. Calcium is a critical mineral that plays a key role in various bodily functions, including muscle function, nerve transmission, and bone health. An imbalance in calcium levels can lead to serious health issues such as muscle weakness, nerve problems, and bone disorders. Therefore, it is essential to keep track of calcium levels to ensure optimal health and safety while using Gemfrac Injection.

Related lab tests for individuals on Gemfrac Injection may include:

1. Serum Calcium Test: This test measures the amount of calcium in the blood and helps to assess overall calcium levels in the body.

2. Ionized Calcium Test: This test specifically measures the ionized form of calcium in the blood, which is the active form and provides a more accurate picture of calcium status.

3. Total Calcium Test: This test measures the total amount of calcium in the blood, including both ionized and bound forms.

4. Parathyroid Hormone (PTH) Test: This test measures the levels of PTH in the blood, which plays a crucial role in regulating calcium levels in the body.

5. Vitamin D Test: Vitamin D is essential for calcium absorption and bone health, so monitoring vitamin D levels can provide valuable insight into calcium metabolism.

Regular monitoring of these lab tests can help healthcare providers ensure the safe and effective use of Gemfrac Injection while maintaining proper calcium balance in the body. It is important to follow healthcare provider recommendations for lab testing schedules to optimize treatment outcomes.


Additional Information

Habit FormingNo
Chemical ClassParathyroid Hormone Analogs
Therapeutic Class-
Action ClassBone formation stimulator -PTH analogue

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 11-Feb-2025