ENDOXAN 500 MG TABLET
By Endoxan
Rx
10 Tablet in a Strip

Composition
Cyclophosphamide(500mg)

Manufacturer - Zydus Cadila
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after
February, 2027
About ENDOXAN 500 MG TABLET
ENDOXAN 500 MG TABLET is a medication used primarily in the treatment of various types of cancers. It is also prescribed for pediatric patients with nephrotic syndrome, a kidney disease, when other treatments have not been effective. Additionally, it may be utilized for other conditions as directed by a healthcare professional.
To ensure optimal results, it is recommended to take ENDOXAN 500 MG TABLET with food, preferably in the morning, at the same time each day. The dosage and frequency will be determined by the doctor based on the individual's condition and may be adjusted as needed. Adhering to the doctor's instructions is crucial, as improper use or exceeding the prescribed amount can result in severe side effects. Although the benefits of the medication may take some time to manifest, it is essential not to discontinue treatment unless advised by the doctor.
Common side effects of ENDOXAN 500 MG TABLET may include vomiting, nausea, hair loss, fever, and blood in urine. Should these side effects persist or worsen, it is important to inform the doctor for possible interventions. Due to its potency, some individuals may experience serious side effects affecting their infection-fighting ability and organ functions. Regular blood tests are typically recommended to monitor for such issues. Increasing fluid intake is advised to promote urine flow, which can help prevent kidney-related complications.
Before commencing treatment with ENDOXAN 500 MG TABLET, it is crucial to inform the doctor about any existing liver or kidney conditions, as well as other medications being taken. This medication can interact with various drugs, potentially causing complications. Not recommended during pregnancy or breastfeeding, ENDOXAN 500 MG TABLET requires both men and women to use effective contraception during treatment to prevent pregnancy.
Benefits
ENDOXAN 500 MG TABLET offers several benefits in treating certain conditions. In cancer treatment, this medication is effective in combating specific types of cancer either on its own or in combination with other drugs. By targeting and either killing or halting the growth of cancer cells, ENDOXAN 500 MG TABLET plays a crucial role in impeding the spread of cancerous cells throughout the body. Additionally, it works to hinder the proliferation of cancer cells, further aiding in the suppression of the disease. It is important to note that this medication is potent and can be highly toxic, underscoring the necessity of consulting with your healthcare provider to fully understand the associated risks and advantages. During the course of treatment with ENDOXAN 500 MG TABLET, it is advised to abstain from consuming alcohol and maintain adequate hydration by drinking plenty of water.
For individuals suffering from nephrotic syndrome, a kidney ailment characterized by excessive protein excretion in the urine and widespread swelling in areas like the eyes, feet, and ankles, ENDOXAN 500 MG TABLET proves to be beneficial. By suppressing the immune system, this medication alleviates inflammation and swelling linked with nephrotic syndrome. Through its mechanism of action, ENDOXAN 500 MG TABLET reduces the levels of protein in the urine and assists in eliminating excess fluid from the body, thereby alleviating the swelling across various body regions. By ameliorating these symptoms, ENDOXAN 500 MG TABLET aids in restoring normal kidney function and serves to prevent further harm to the kidneys.
How to use the ENDOXAN 500 MG TABLET
To use ENDOXAN 500 MG TABLET, follow your doctor's instructions on dosage and duration carefully. Swallow the tablet whole with a glass of water, avoiding chewing, crushing, or breaking it. Remember to take ENDOXAN 500 MG TABLET with food to help improve its absorption and reduce the risk of stomach upset. If you have any questions or concerns about how to use this medication, consult your healthcare provider for guidance.
Uses of ENDOXAN 500 MG TABLET
ENDOXAN 500 MG TABLET is commonly used in the treatment of cancer and nephrotic syndrome. In cancer treatment, it is prescribed to slow down or stop the growth of cancer cells. The medication works by interfering with the DNA replication process in cancer cells, thus preventing their proliferation. For patients with nephrotic syndrome, ENDOXAN 500 MG TABLET is recommended to suppress an overactive immune system that is attacking the kidneys. By reducing the immune response, this medication helps in managing the symptoms of nephrotic syndrome. It is important to follow the prescribed dosage and schedule as directed by a healthcare provider when using ENDOXAN 500 MG TABLET for these conditions.
What conditions ENDOXAN 500 MG TABLET treats?
ENDOXAN 500 MG TABLET is used to treat certain types of cancers and nephrotic syndrome in children when other treatments have not been effective. In cancer, it helps by killing or halting the growth of cancer cells. In nephrotic syndrome, a kidney disorder causing excessive protein in urine and swelling, it works by reducing inflammation and swelling, restoring kidney function. It's important to take ENDOXAN with food daily as prescribed by your doctor to maximize benefits. Side effects like vomiting, nausea, and hair loss may occur, and regular blood tests are necessary. It's crucial to avoid alcohol and stay hydrated during treatment.
Should you consult a doctor?
If you experience persistent or worsening side effects such as vomiting, nausea, hair loss, fever, or blood in the urine while taking ENDOXAN 500 MG TABLET, it is important to seek medical attention. These side effects can be common but can also indicate serious issues that need to be addressed by your doctor. Additionally, if you have any concerns or notice new symptoms that worry you, it is recommended to consult your healthcare provider. Remember that this medication is potent and may affect your body in various ways, so it's crucial to keep your doctor informed about any changes or difficulties you may be experiencing. In case of severe side effects or any unexpected reactions, do not hesitate to contact your healthcare provider promptly for guidance and appropriate management. It's essential to prioritize your health and well-being while undergoing treatment with ENDOXAN 500 MG TABLET.
Side effects of ENDOXAN 500 MG TABLET
When taking ENDOXAN 500 MG TABLET, you may experience certain side effects, although most of them usually fade away as your body gets used to the medication. However, if any of these side effects persist or cause concern, it is important to consult your doctor. Common side effects may include vomiting, nausea, hair loss, fever, blood in the urine, diarrhea, and a decrease in white blood cell count, specifically neutrophils. Remember, your doctor is your best resource for managing any side effects you may encounter while taking this medication.
Safety advice

liver
When using ENDOXAN 500 MG TABLET, caution is advised for patients with liver disease. It may be necessary to adjust the dosage of ENDOXAN 500 MG TABLET for individuals with liver issues. It is important to consult your doctor regarding the use of this medication to ensure it is safe and appropriate for your condition.

kidney
ENDOXAN 500 MG TABLET requires caution in severe kidney disease. Adjustments to the dose might be necessary. Consult your doctor for guidance.

alcohol
It is not safe to drink alcohol while taking ENDOXAN 500 MG TABLET. Be cautious about consuming alcohol with this medication.

driving
ENDOXAN 500 MG TABLET may cause side effects like dizziness, blurred vision, and visual impairment that can impact driving ability.

pregnancy
ENDOXAN 500 MG TABLET should not be used during pregnancy as there is a clear risk to the baby's development. Only in critical situations where benefits outweigh risks, a doctor may consider it. Seek advice from your healthcare provider.

breastfeeding
ENDOXAN 500 MG TABLET is not recommended during breastfeeding due to potential harm to the baby. Toxicity risk exists, so caution is advised.
Consumption warning before consuming ENDOXAN 500 MG TABLET
Before consuming ENDOXAN 500 MG TABLET, it is crucial to follow certain guidelines to ensure safe and effective use of this medication. This medicine is primarily used in the treatment of various cancers and nephrotic syndrome in children when other treatments have not been successful. It should always be taken with food, preferably in the morning, at the same time each day to maximize its benefits. Your doctor will determine the appropriate dosage and frequency of intake, which may vary based on your condition. Taking this medication incorrectly or in excess can result in severe side effects.
Common side effects of ENDOXAN 500 MG TABLET include vomiting, nausea, hair loss, fever, and blood in urine. If these side effects persist or worsen, consult your doctor for potential remedies. This medicine is potent and may weaken your immune system, affecting blood, liver, or kidney functions. Regular blood tests are recommended to monitor these effects. Ensure adequate hydration to prevent bladder and kidney complications.
Prior to taking ENDOXAN 500 MG TABLET, inform your doctor about any liver or kidney issues, ongoing infections, or medications being used. Avoid this medicine during pregnancy or breastfeeding as it may harm the baby. Both males and females should use effective contraception during treatment to prevent pregnancy.
Related lab tests
When taking ENDOXAN 500 MG TABLET, it's important to monitor certain lab tests to ensure your health and safety. The related lab tests for this medication include:
1. Prothrombin Time: This test measures how long it takes for your blood to clot, which is crucial for monitoring the risk of bleeding or clotting disorders while on ENDOXAN 500 MG TABLET.
2. Triglycerides: Monitoring triglyceride levels is important as ENDOXAN 500 MG TABLET can affect lipid metabolism, leading to potential changes in triglyceride levels which can impact heart health.
3. Urine Albumin: This test checks for the presence of albumin in the urine, which can indicate kidney damage or disease. Regular monitoring of urine albumin levels is necessary while on ENDOXAN 500 MG TABLET to ensure kidney function is not compromised.
It is recommended to undergo these lab tests regularly as advised by your healthcare provider to closely monitor any potential side effects or complications associated with ENDOXAN 500 MG TABLET.
Additional Information
Habit Forming | No |
Chemical Class | Nitrogen Mustard Compounds |
Therapeutic Class | - |
Action Class | Alkylating agent |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹43.47
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Content verified by

Dr. Mansi Chaudhari
MBBS - General Medicine
Last update on 11-Feb-2025