ACTEMRA 400 MG INJECTION

By Actemra

Rx

1 Injection in a Vial

Composition icon

Composition

Tocilizumab(400mg)

Manufacturer - Roche Products India Pvt Ltd icon

Manufacturer - Roche Products India Pvt Ltd

1503, 15th Floor, 'The Capital', Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Expires on or after icon

Expires on or after

March, 2027

About ACTEMRA 400 MG INJECTION

ACTEMRA 400 MG INJECTION is a medication prescribed to manage various inflammatory conditions affecting the joints, skin, and bowel. Conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, psoriasis, ulcerative colitis, and Crohn’s disease can be treated with this medication. The active component in ACTEMRA 400 MG INJECTION works by blocking TNF alpha, which helps in reducing swelling associated with these conditions.

It is important to note that ACTEMRA 400 MG INJECTION should only be administered by a healthcare professional and should not be self-administered. To maximize the benefits of this medication, it should be taken regularly at the same time each day as advised by your healthcare provider. Even if you start feeling better, it is crucial to complete the full course of treatment to ensure effectiveness.

Like any other medication, ACTEMRA 400 MG INJECTION may cause some side effects. Common side effects may include headache, high blood pressure, upper respiratory tract infection, increased liver enzymes, and nasopharyngitis (throat pain or irritation). If you experience any of these side effects and they persist or become bothersome, it is important to consult your doctor. Your healthcare provider can provide guidance on managing or preventing these symptoms. Additionally, individuals undergoing treatment with ACTEMRA 400 MG INJECTION may have a higher susceptibility to infections. Immediate medical attention is required if you develop symptoms of an infection such as fever, cough, rash, loose stools, or flu-like symptoms.

Prior to starting treatment with ACTEMRA 400 MG INJECTION, it is essential to inform your doctor about any existing heart, kidney, or liver conditions you may have. Your healthcare provider should also be informed about all other medications you are currently taking to avoid potential interactions. During the course of treatment, regular blood tests may be conducted by your doctor to monitor your blood counts and ensure the medication is not affecting them adversely. Pregnant and breastfeeding women should seek advice from their healthcare providers before using this medication to ensure safety for themselves and their baby.


Benefits

ACTEMRA 400 MG INJECTION offers several benefits in treating various conditions. When used in the treatment of Ankylosing spondylitis, this medication helps alleviate severe pain and stiffness in the spine by reducing the activity of chemicals responsible for pain and swelling. By slowing down the progression of the disease, ACTEMRA 400 MG INJECTION also minimizes the risk of long-term disability. Although its effects may not be immediate, this slow-acting medicine proves to be highly effective over time, emphasizing the importance of adherence to the prescribed dosage.

In the case of Rheumatoid arthritis, ACTEMRA 400 MG INJECTION plays a key role in managing this autoimmune disorder by normalizing the immune system's function and preventing it from attacking the joints' lining. This results in relief from pain, swelling, and stiffness in the joints, enhancing mobility and enabling individuals to carry out daily activities with greater ease. Notably, relief from joint symptoms can be experienced within the first 8 weeks of treatment with this medication.

For individuals with Psoriasis, ACTEMRA 400 MG INJECTION helps in reducing the formation of scaly, itchy patches on the body, particularly in areas such as the elbows, knees, scalp, and lower back. By addressing these symptoms, the medication improves skin condition, reducing dryness and enhancing overall self-confidence. While it may take some time to achieve optimal results, consistent and proper usage as directed by a healthcare provider is crucial for maximizing its benefits.

Furthermore, in the treatment of Ulcerative colitis, ACTEMRA 400 MG INJECTION proves effective in reducing redness and swelling in the large intestine and rectum, alleviating symptoms such as bleeding, frequent stool passage, and stomach pain. By providing relief from discomfort, this medication enables individuals to lead a more normal life and helps in preventing the reoccurrence or worsening of ulcerative colitis flare-ups. Adequate hydration is recommended while using this medication to support its efficacy.

Lastly, in addressing Crohn’s disease, ACTEMRA 400 MG INJECTION aids in managing the redness and swelling that occur along the digestive system, offering relief from severe stomach pain. By targeting the chemicals responsible for pain and swelling, this medication assists individuals in living a more normal life. Ensuring compliance with the prescribed dosage is essential for obtaining the full benefits of ACTEMRA 400 MG INJECTION in managing these various conditions effectively.


How to use the ACTEMRA 400 MG INJECTION

To use ACTEMRA 400 MG INJECTION, you should always allow your doctor or nurse to administer the medicine to you. Please do not try to give yourself the injection, as it is essential to have a healthcare professional handle it for you. This ensures that the injection is done correctly and safely. By following these instructions, you can benefit from the intended effects of the medication. Be sure to consult your healthcare provider if you have any questions or concerns about the proper usage of ACTEMRA 400 MG INJECTION.


Uses of ACTEMRA 400 MG INJECTION

ACTEMRA 400 MG INJECTION is used for the treatment of various inflammatory conditions, helping patients manage their symptoms effectively. It is commonly prescribed for Ankylosing spondylitis, a type of arthritis that affects the spine, leading to pain and stiffness. This medication is also beneficial in treating Rheumatoid arthritis, a chronic inflammatory disorder that affects the joints, causing pain and swelling. ACTEMRA 400 MG INJECTION is also used in the management of Psoriasis, a skin condition characterized by red, itchy patches. Additionally, it is effective in treating Ulcerative colitis and Crohn's disease, both of which are inflammatory bowel conditions that cause discomfort and can affect a person's quality of life. Consulting a healthcare professional is essential to determine the appropriate dosage and frequency of administration based on individual needs.


What conditions ACTEMRA 400 MG INJECTION treats?

ACTEMRA 400 MG INJECTION is used to treat various inflammatory conditions affecting the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). In ankylosing spondylitis, it helps reduce pain and stiffness in the spine. For rheumatoid arthritis, it normalizes the immune system to relieve pain and swelling. In psoriasis, it reduces scaly patches and dryness on the skin. And for ulcerative colitis and Crohn’s disease, it decreases pain and swelling in the intestines. Take the medication as prescribed for the best results.


Should you consult a doctor?

If you experience persistent side effects such as headache, high blood pressure, upper respiratory tract infection, or injection site reactions from ACTEMRA 400 MG INJECTION, it's advisable to consult your doctor. Additionally, if you notice any symptoms suggesting an infection like fever, cough, rash, loose stools, or flu-like symptoms, seek immediate medical attention. Inform your doctor about any existing heart, kidney, or liver issues, as well as all other medications you are taking. Regular monitoring of your blood counts through blood tests during treatment is essential to ensure the medicine is not affecting them adversely. Pregnant or breastfeeding individuals should seek guidance from their healthcare provider before using this medication. Remember, most side effects typically diminish as your body adjusts to the treatment, but persistent or concerning symptoms warrant medical intervention.


Side effects of ACTEMRA 400 MG INJECTION

Side effects may occur when using ACTEMRA 400 MG INJECTION, but most of them are not serious and go away as your body gets used to the medication. However, it's important to talk to your doctor if you experience any persistent side effects or if you are concerned about them. Some common side effects of ACTEMRA 400 MG INJECTION include headache, high blood pressure, upper respiratory tract infection, and reactions at the injection site such as pain, swelling, and redness.


Safety advice

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liver

When using ACTEMRA 400 MG INJECTION, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment when taking this medication. It is crucial to consult your doctor before using ACTEMRA 400 MG INJECTION. If you have active liver disease, it is not recommended to use this medication. Be mindful of your liver health and always seek medical advice before starting treatment with ACTEMRA 400 MG INJECTION.

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kidney

ACTEMRA 400 MG INJECTION should be used carefully if you have kidney issues. Adjusting the dose may be necessary, so always speak with your doctor. Limited data is available on its use in moderate to severe kidney disease; no dose adjustment is needed for mild kidney disease.

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alcohol

When taking ACTEMRA 400 MG INJECTION, it is safe to consume alcohol as it does not result in any harmful side effects.

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driving

ACTEMRA 400 MG INJECTION may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if experiencing these effects.

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pregnancy

ACTEMRA 400 MG INJECTION may not be safe to use during pregnancy. Animal studies have shown potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing. Please consult your doctor before using.

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breastfeeding

ACTEMRA 400 MG INJECTION is likely safe for breastfeeding moms. Limited data shows it poses no major risk to babies.


Consumption warning before consuming ACTEMRA 400 MG INJECTION

Before consuming ACTEMRA 400 MG INJECTION, it is vital to remember that this medication is used to address various inflammatory conditions like rheumatoid arthritis and psoriasis by reducing swelling through blocking TNF alpha. This injection should only be administered by a healthcare professional and not by yourself. For maximum benefit, ensure regular use at the same time daily as prescribed by your doctor, even if you start feeling better. Common side effects may include headaches, high blood pressure, and increased liver enzymes. Contact your doctor if these side effects persist. Moreover, be cautious about potential infections while on this treatment, promptly informing your doctor if any symptoms arise. Prior to taking this medication, consult your doctor if you have heart, kidney, or liver issues, and disclose all current medications. Routine blood tests may be necessary during treatment to monitor your blood counts. Pregnant and breastfeeding individuals should seek advice from their healthcare provider before using this medication.


What if you forgot to take ACTEMRA 400 MG INJECTION?

If you miss a dose of ACTEMRA 400 MG INJECTION, it is important to consult your doctor. It is advisable to seek guidance from your healthcare provider to understand the appropriate steps to take in case of a missed dose. Maintaining open communication with your doctor can help ensure that you receive the most effective treatment for your condition. Remember that your doctor is there to support you in managing your medication regimen, so do not hesitate to reach out if you have any concerns about missed doses.


Related lab tests

Related Lab Tests:

When taking ACTEMRA 400 MG INJECTION, it may be necessary to monitor certain lab tests to ensure your safety and effectiveness of the treatment. The following tests are commonly recommended:

1. Anti Neutrophilic Cytoplasmic Antibody (P-ANCA): This test can help in detecting autoimmune conditions like vasculitis.

2. Anti Saccharomyces Cerevisiae (ASCA), IgA and IgG: These tests are used to aid in the diagnosis of inflammatory bowel diseases like Crohn's disease.

3. C-Reactive Protein Quantitative (CRP): This test measures inflammation in the body and can help in monitoring the response to therapy.

4. Erythrocyte Sedimentation Rate (ESR): This test helps in detecting inflammatory conditions like arthritis.

5. HLA-B27, PCR: This test is commonly used to aid in the diagnosis of autoimmune diseases such as ankylosing spondylitis.

6. Rheumatoid Factor - Agglutination and Turbidometry: These tests can help in diagnosing and monitoring rheumatoid arthritis.

7. Rheumatoid Factor IgG Antibody: This test is helpful in detecting autoimmune conditions like rheumatoid arthritis.

It is important to discuss with your healthcare provider about the necessity of these lab tests while undergoing treatment with ACTEMRA 400 MG INJECTION.


Additional Information

Habit FormingNo
Chemical ClassMonoclonal Antibody
Therapeutic Class-
Action ClassDisease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Monie Riju Simon

MBBS - General Medicine

Last update on 11-Feb-2025