ACTEMRA 200 MG INJECTION
By Actemra
Rx
1 Injection in a Vial

Composition
Tocilizumab(200mg)

Manufacturer - Roche Products India Pvt Ltd
1503, 15th Floor, 'The Capital', Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Expires on or after
March, 2027
About ACTEMRA 200 MG INJECTION
ACTEMRA 200 MG INJECTION is a medication designed to address various inflammatory conditions affecting the joints, skin, and bowel. It is commonly utilized in the treatment of conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, psoriasis, ulcerative colitis, and Crohn’s disease. This medication works by reducing swelling in these conditions through the inhibition of TNF alpha, a protein involved in the inflammatory process.
Administration and Compliance:
It is essential to note that ACTEMRA 200 MG INJECTION should only be administered by a qualified healthcare professional and should not be self-administered. To derive the maximum benefit from this medication, it is crucial to adhere to a regular dosing schedule, taking it at the same time each day as prescribed by your doctor. Even if you start feeling better during the course of treatment, it is imperative to continue the full prescribed dose.
Potential Side Effects and Monitoring:
Common side effects associated with ACTEMRA 200 MG INJECTION may include headaches, elevated blood pressure, upper respiratory tract infections, increased liver enzymes, and nasopharyngitis. Should any of these side effects persist or become bothersome, it is advisable to consult your doctor. Additionally, individuals undergoing treatment with this medication may be more susceptible to infections. Therefore, it is important to promptly inform your healthcare provider if you experience symptoms such as fever, cough, rash, loose stools, or flu-like symptoms.
Safety Precautions and Monitoring:
Prior to commencing treatment with ACTEMRA 200 MG INJECTION, it is essential to inform your doctor about any pre-existing heart, kidney, or liver issues. Your doctor should also be made aware of all other medications you are currently taking to prevent potential interactions. During the course of treatment, your doctor may conduct regular blood tests to monitor your blood counts and ensure that the medication is not adversely affecting them. For pregnant and breastfeeding individuals, seeking advice from their healthcare providers before initiating the use of this medication is crucial to ensure safety for both the individual and the baby.
Benefits
ACTEMRA 200 MG INJECTION offers various benefits depending on the condition being treated. For individuals with Ankylosing spondylitis, a condition that leads to severe pain and stiffness in the spine, ACTEMRA 200 MG INJECTION works by reducing the activity of chemicals that cause pain and swelling. Not only does it alleviate immediate symptoms, but it also slows down disease progression and minimizes the risk of long-term disability. Although it may not provide instant relief, its effectiveness becomes evident over time, emphasizing the importance of strict adherence to the prescribed dosage regimen.
In the case of Rheumatoid arthritis (RA), an autoimmune disorder characterized by joint pain and swelling due to immune system dysfunction, ACTEMRA 200 MG INJECTION plays a crucial role in restoring normal immune function. By preventing the immune system from attacking the body, this medication offers relief from joint symptoms such as pain, swelling, and stiffness. Most individuals may experience an improvement in joint swelling and discomfort within the first 8 weeks of treatment, enabling easier movement and enhancement of daily activities.
For individuals suffering from Psoriasis, a skin condition characterized by rapid cell growth leading to itchy patches and scales, ACTEMRA 200 MG INJECTION proves effective in reducing the development of scaly, itchy patches on various body parts. Additionally, it helps improve skin dryness associated with Psoriasis, thereby enhancing self-confidence and overall quality of life. While it may take some time to show full effectiveness, consistent and prolonged use as prescribed by the healthcare provider is essential to maximize its benefits.
Moreover, ACTEMRA 200 MG INJECTION also offers relief for individuals with Ulcerative colitis, a condition causing inflammation in the large intestine and rectum, resulting in symptoms like bleeding, frequent stools, and stomach pain. By reducing swelling and discomfort, this medication aids in alleviating these symptoms and enabling individuals to lead a normal life. Following the prescribed usage guidelines, maintaining hydration, and ensuring proper fluid intake can help prevent the recurrence of Ulcerative colitis flare-ups.
Lastly, for those dealing with Crohn's disease, which triggers inflammation in various parts of the digestive system leading to abdominal pain, ACTEMRA 200 MG INJECTION acts by blocking the chemicals responsible for pain and swelling. By providing relief and supporting a normal lifestyle, this injection-based medication proves beneficial in managing the symptoms of the disease. It is essential to strictly adhere to the prescribed dosage in order to optimize its therapeutic effects and improve overall quality of life.
How to use the ACTEMRA 200 MG INJECTION
To use ACTEMRA 200 MG INJECTION, it is important to have your doctor or nurse administer the medicine for you. It should not be self-administered. This injection is typically given in a healthcare setting by a healthcare professional. It is crucial to follow your healthcare provider's instructions carefully. ACTEMRA should not be injected by yourself at home. Inform your healthcare provider if you have any questions or concerns about how to use this medication. By receiving the injection from a trained professional, you can ensure proper administration and maximize the potential benefits of ACTEMRA for your treatment.
Uses of ACTEMRA 200 MG INJECTION
ACTEMRA 200 MG INJECTION is utilized for various medical conditions including Ankylosing spondylitis, Rheumatoid arthritis, Psoriasis, Ulcerative colitis, and Crohn’s disease. It is commonly used in the management and treatment of these conditions to provide relief and improve patients' quality of life. For Ankylosing spondylitis, ACTEMRA 200 MG INJECTION helps in reducing inflammation and easing symptoms related to this condition. In cases of Rheumatoid arthritis, the injection is effective in controlling joint pain and swelling. Psoriasis, Ulcerative colitis, and Crohn’s disease all benefit from ACTEMRA 200 MG INJECTION, as it helps to alleviate symptoms and manage the underlying causes of these conditions effectively.
What conditions ACTEMRA 200 MG INJECTION treats?
ACTEMRA 200 MG INJECTION is used to treat inflammatory conditions affecting joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowels (ulcerative colitis, Crohn's disease), by reducing swelling. Ankylosing spondylitis causes severe pain and stiffness in the spine; ACTEMRA 200 MG INJECTION helps slow down the disease progression. In rheumatoid arthritis, it normalizes the immune system to reduce joint pain and swelling. For psoriasis, it reduces itchy patches and dryness. In ulcerative colitis and Crohn’s disease, it alleviates pain and swelling in the intestines, helping prevent flare-ups.
Should you consult a doctor?
If you experience persistent side effects such as headache, high blood pressure, upper respiratory tract infection, increased liver enzymes, or nasopharyngitis while using ACTEMRA 200 MG INJECTION, it is important to consult your doctor. Additionally, be vigilant for signs of infection like fever, cough, rash, loose stools, or flu-like symptoms, and promptly inform your healthcare provider if you develop any of these symptoms. It is crucial to notify your doctor about any existing heart, kidney, or liver issues, as well as disclose all other medications you are taking. Regular monitoring of blood counts may be necessary during treatment with this medicine. Pregnant or breastfeeding individuals should seek advice from their healthcare providers before using ACTEMRA 200 MG INJECTION. Remember, most side effects tend to subside as your body adjusts, but persistent or concerning symptoms should always be discussed with your doctor.
Side effects of ACTEMRA 200 MG INJECTION
When using ACTEMRA 200 MG INJECTION, you may experience some side effects. These side effects are usually mild and go away as your body gets used to the medication. If you find the side effects bothersome or if they persist, it's important to talk to your doctor. Common side effects of ACTEMRA 200 MG INJECTION include headaches, high blood pressure, upper respiratory tract infections, and injection site reactions such as pain, swelling, and redness. Remember to seek medical advice if you have any concerns about these side effects.
Safety advice

liver
ACTEMRA 200 MG INJECTION needs to be used carefully in individuals with liver conditions. It might be necessary to adjust the dosage of ACTEMRA 200 MG INJECTION when being administered to patients with liver disease. It is important to seek advice from your doctor before using this medication. It is advisable not to use ACTEMRA 200 MG INJECTION in individuals with ongoing liver disease.

kidney
ACTEMRA 200 MG INJECTION should be used carefully in patients with kidney disease. Adjusting the dose may be necessary, so it's important to talk to your doctor. Limited details are known for using ACTEMRA 200 MG INJECTION in patients with moderate to severe kidney issues. Patients with mild kidney problems do not need dose adjustment.

alcohol
When taking ACTEMRA 200 MG INJECTION, it is safe to consume alcohol as it does not lead to adverse effects. There is no specific safety advice regarding alcohol consumption with this medication.

driving
When using ACTEMRA 200 MG INJECTION, be cautious when driving as it may reduce alertness, impact vision, cause drowsiness, or dizziness. Avoid driving if experiencing these effects.

pregnancy
ACTEMRA 200 MG INJECTION should be avoided during pregnancy as it may be harmful to the developing baby based on animal studies. Your doctor will assess the benefits and risks before prescribing it. Kindly seek advice from your doctor.

breastfeeding
ACTEMRA 200 MG INJECTION is likely safe during breastfeeding based on limited human data showing no significant risk to the baby.
Consumption warning before consuming ACTEMRA 200 MG INJECTION
Before using ACTEMRA 200 MG INJECTION, know that it is used to treat inflammatory conditions such as arthritis, psoriasis, and bowel diseases by reducing swelling through TNF alpha blocking. It should only be administered by a healthcare professional, not by yourself. Take it regularly at the same time daily as prescribed by your doctor, even if you start feeling better. Common side effects may include headache, high blood pressure, infections, and liver issues. Inform your doctor if these side effects persist. Be vigilant for signs of infections like fever, cough, rash, or flu-like symptoms. Prior to starting treatment, disclose any heart, kidney, or liver issues to your doctor, along with all other medications you are taking. Regular blood tests may be necessary during treatment. Pregnant or breastfeeding individuals should consult their healthcare provider before using this medication.
What if you forgot to take ACTEMRA 200 MG INJECTION?
If you happen to miss a dose of ACTEMRA 200 MG INJECTION, it is important to consult your doctor for guidance. It is recommended to reach out to your healthcare provider to discuss the best course of action in case a dose is missed. Your doctor will be able to provide you with appropriate instructions on what steps to take in the event of a missed dose. Remember that it is crucial to follow your doctor's recommendations closely to ensure the effectiveness of your treatment plan.
Related lab tests
When taking ACTEMRA 200 MG INJECTION, there are several related lab tests that may be ordered by your healthcare provider to monitor your health and the effectiveness of the treatment. These include:
1. Anti Neutrophilic Cytoplasmic Antibody (ANCA) - This test helps in diagnosing autoimmune disorders like vasculitis.
2. Anti Saccharomyces Cerevisiae (ASCA) IgA and IgG - These tests are used to detect antibodies associated with conditions like Crohn's disease and other inflammatory bowel diseases.
3. C-Reactive Protein (CRP) Quantitative - This test measures the level of inflammation in the body and helps assess response to treatment.
4. Erythrocyte Sedimentation Rate (ESR) - This test also indicates the presence of inflammation and can be used to monitor response to treatment.
5. HLA-B27 PCR - This test looks for a specific genetic marker associated with conditions like ankylosing spondylitis and other autoimmune diseases.
6. Rheumatoid Factor (RF) - Agglutination and Turbidometry - These tests are used to detect antibodies in conditions like rheumatoid arthritis.
7. Rheumatoid Factor IgG Antibody - This test specifically measures IgG antibodies associated with rheumatoid arthritis.
These lab tests are valuable tools in assessing your condition and response to ACTEMRA treatment. Your healthcare provider will interpret the results and tailor your treatment plan accordingly to ensure the best possible outcomes.
Additional Information
Habit Forming | No |
Chemical Class | Monoclonal Antibody |
Therapeutic Class | - |
Action Class | Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics |
FAQs
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Content verified by

Dr. Monie Riju Simon
MBBS - General Medicine
Last update on 11-Feb-2025