Accentrix Solution for Injection

By Accentrix

Rx

1 Solution for Injection in a Vial

Composition icon

Composition

Ranibizumab(10mg/ml)

Manufacturer - Novartis India Ltd icon

Manufacturer - Novartis India Ltd

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Expires on or after icon

Expires on or after

February, 2027

About Accentrix Solution for Injection

Accentrix Solution for Injection is a medication used to treat various eye diseases, including those caused by diabetes, macular degeneration, and macular swelling. It works by reducing the abnormal growth and leakage of blood vessels in the eye that can lead to vision loss. This injection is meant to be administered directly into the eyeball by an eye specialist and should not be self-administered at home.

One variant of this medication is Accentrix Livi 0.5 mg Injection 1's, which belongs to the group of medicines known as anti-neovascularisation agents. It is used to address eye diseases that result in vision impairment, such as neovascular age-related macular degeneration, macular edema following retinal vein occlusion, diabetic macular edema, and proliferative diabetic retinopathy. Additionally, it is utilized to treat retinopathy of prematurity in premature babies.

Accentrix Livi 0.5 mg Injection 1's contains Ranibizumab, which is a vascular endothelial growth factor A (VEGF-A) antagonist. Ranibizumab binds to VEGF-A, a protein responsible for abnormal blood vessel growth and swelling in the eyes that can lead to vision issues. By blocking the action of VEGF-A, this medication prevents abnormal growth and swelling, thereby helping to stabilize and improve vision.

While the injection can be beneficial, there are potential side effects to consider. These may include eye pain, inflammation, retinal bleeding, dry eye, eye irritation, redness, or itching of the eye. Most of the side effects tend to resolve over time and may not require medical attention. However, it is important to consult your doctor if any side effects persist or worsen. It is also essential to inform your doctor if you are allergic to any components in Accentrix Livi 0.5 mg Injection 1's, if you are pregnant, think you may be pregnant, or planning for pregnancy. Additionally, this medication is not recommended during breastfeeding. Be sure to keep your doctor informed about your health condition and medications to avoid any potential side effects or interactions.


Benefits

Accentrix Solution for Injection, also known as Accentrix Livi 0.5 mg Injection 1's, offers a range of benefits in treating various eye conditions. In diabetic eye disease, which can result in vision loss or blindness, this medication works to prevent damage caused by diabetes and halt the progression of vision deterioration. By targeting the root cause of the issue, Accentrix Solution for Injection helps preserve eye health and clarity of vision for individuals experiencing diabetic eye disease.

Moreover, in cases of wet age-related macular degeneration, where abnormal blood vessels cause leakage leading to vision problems, this medication plays a crucial role in preventing the leakage of these vessels. By administering Accentrix Solution for Injection as prescribed by a healthcare professional, individuals can reduce the risk of vision loss associated with this condition, thus safeguarding their central vision and overall eye health.

Furthermore, for individuals suffering from macular edema due to retinal vein occlusion, a condition that can result in swelling of the macula and vision disturbances, Accentrix Solution for Injection provides relief by addressing the underlying cause of the swelling. By treating the macular edema effectively, this medication helps alleviate vision disturbances and supports optimal eye function, enhancing the overall quality of life for the individual.

Overall, Accentrix Solution for Injection, containing the active ingredient Ranibizumab, a VEGF-A antagonist, works by blocking the action of VEGF-A protein that leads to abnormal blood vessel growth and swelling in the eyes. This targeted approach helps stabilize and improve vision for individuals undergoing treatment for various eye conditions such as neovascular age-related macular degeneration, macular edema following retinal vein occlusion, and diabetic eye diseases. Additionally, this medication may also be used for the treatment of retinopathy of prematurity in preterm infants, underscoring its versatility and effectiveness in addressing vision impairment in different patient populations. Consult your doctor for personalized guidance on the benefits of Accentrix Solution for Injection based on your specific eye health needs.


How to use the Accentrix Solution for Injection

To use Accentrix Solution for Injection, it is important to follow your doctor's or nurse's instructions carefully. This medicine is given in two forms - through an injection into your eye or as an implant inserted into the white part of your eye. Only a healthcare professional should administer this medication, so do not try to do it yourself. If you are receiving the injection, your eye doctor will carefully inject the solution into your eye. If you are getting the implant, a doctor in a medical office or clinic will insert it into the white part of your eye using a needle. It is essential to have these procedures done by trained professionals to ensure the medication is given correctly and to prevent any complications. Always consult with your healthcare provider if you have any questions or concerns about using Accentrix Solution for Injection.


Uses of Accentrix Solution for Injection

Accentrix Solution for Injection is used to treat various eye conditions including wet age-related macular degeneration, macular edema due to retinal vein occlusion, and diabetic eye disease. This solution is particularly effective in treating neovascular age-related macular degeneration, diabetic macular edema, proliferative diabetic retinopathy, and choroidal neovascularization. It can also be beneficial in managing macular edema following retinal vein occlusion. In addition, Accentrix is employed in premature infants to address retinopathy of prematurity.


What conditions Accentrix Solution for Injection treats?

Accentrix Solution for Injection is used to treat various eye conditions such as Neovascular (wet) age-related macular degeneration (AMD), Macular oedema, Retinal vein occlusion (RVO), Diabetic macular oedema (DME), Proliferative diabetic retinopathy (PDR), and Retinopathy of prematurity (ROP). These conditions can lead to vision problems like blurred vision, vision loss, and other symptoms related to the macula and retina. By targeting and addressing the underlying causes of these diseases, Accentrix Solution aims to help improve vision and manage associated complications.


Should you consult a doctor?

If you experience any of the common side effects of Accentrix Solution for Injection such as conjunctival hemorrhage, eye pain, eye floaters, increased intraocular pressure, or eye inflammation, it is important to consult your doctor if they worsen or persist. Do not hesitate to seek medical attention if you are worried about these side effects. It is crucial to remember that driving after receiving this injection is not advised as it may lead to temporary blurring of vision.

Other symptoms that may require medical attention include blurred vision, nausea, dry eye, eye itching, cataract, vitreous floaters, vitreous detachment, intraocular inflammation, eye irritation, increased lacrimation, eyelid inflammation, ocular hyperemia, retinal disorder, maculopathy, eye discomfort, posterior capsule opacification, injection site hemorrhage, nasopharyngitis, anemia, joint pain, renal failure, peripheral neuropathy, gastro-esophageal reflux disease, hypercholesterolemia, and bronchitis. Always inform your healthcare provider about any concerns or persistent side effects for proper evaluation and guidance.


Side effects of Accentrix Solution for Injection

When using Accentrix Solution for Injection, some side effects may occur. These effects are usually mild and temporary, often resolving as your body becomes accustomed to the medication. However, if any of the following side effects persist or cause concern, it is important to consult your doctor promptly. These side effects include conjunctival hemorrhage, eye pain, increased intraocular pressure, foreign body sensation in the eyes, blurred vision, nausea, dry eye, eye itching, cataract, vitreous floaters, vitreous detachment, intraocular inflammation, eye irritation, increased lacrimation, eyelid inflammation, ocular hyperemia, retinal disorder, maculopathy, eye discomfort, posterior capsule opacification, injection site hemorrhage, nasopharyngitis (inflammation of the throat and nasal passages), anemia (low red blood cell count), joint pain, renal failure, peripheral neuropathy (tingling and numbness in feet and hands), gastro-esophageal reflux disease, hypercholesterolemia (high cholesterol), and bronchitis (inflammation of the airways). Some eye-specific side effects to watch for are inflammation of the eye, retinal bleeding, eye pain, bloodshot eye, small particles or spots in vision, eye irritation, dry eye, redness or itching of the eye, and increased eye pressure. If any of these side effects persist or become bothersome, it is advisable to seek medical advice.


Safety advice

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liver

When it comes to using Accentrix Solution for Injection, it appears to be safe for patients with liver disease based on the limited data available. There is no clear indication that a dosage adjustment is necessary for individuals with liver issues. However, it is always advisable to consult your doctor before starting any treatment to ensure the best possible outcome.

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kidney

Limited data suggests Accentrix Solution for Injection is likely safe for patients with kidney disease; dosage adjustment may not be necessary. Consult your doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Accentrix Solution for Injection.

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driving

After using Accentrix Solution for Injection, your vision may be blurry briefly. It is advised not to drive until your vision clears.

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pregnancy

Accentrix Solution for Injection may not be safe during pregnancy. Animal studies indicate potential harm to the baby. Your doctor will assess risks versus benefits before prescribing. Kindly seek medical advice.

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breastfeeding

Accentrix Solution for Injection is believed to be safe for use during breastfeeding. Human data shows it poses minimal risk to the baby.


Consumption warning before consuming Accentrix Solution for Injection

Before using Accentrix Solution for Injection, do not proceed if you are allergic to any of its components, have an eye infection, severe intraocular inflammation, or if you are breastfeeding. It is crucial to consult your doctor if you are pregnant, suspect pregnancy, or planning for pregnancy. In case you notice worsening eye redness, pain, increased discomfort, more small particles in your vision, blurred vision, reduced vision, or heightened light sensitivity, seek immediate medical help. Share your medical history of eye conditions, treatments, or stroke with your doctor. Additionally, inform your doctor about all medications, supplements, or herbal products you are currently taking.


Disease interactions

When using Accentrix Solution for Injection, it is important to inform your doctor if you have had an eye infection, eye inflammation, or stroke. These conditions can interact with the medication and may impact its effectiveness or cause additional complications. By sharing this information with your healthcare provider, they can assess the potential risks and benefits of using Accentrix Solution for Injection in relation to your specific medical history. This will help ensure that you receive the most appropriate treatment tailored to your individual health needs.


What if you forgot to take Accentrix Solution for Injection?

If you forget to take a dose of Accentrix Solution for Injection, it is important to reach out to your doctor for guidance. Consult with your healthcare provider if a dose is missed to ensure that you receive proper care and instructions.


Related lab tests

The Accentrix Solution for Injection may require monitoring through several related lab tests to ensure its effectiveness and safety. These tests include Fasting Blood Glucose, which measures the amount of sugar in your blood after not eating for a period of time. Postprandial Blood Glucose test checks your blood sugar levels after meals. It helps in understanding how your body processes sugar after eating. Glycosylated Hemoglobin, also known as an A1c test, provides information about your average blood sugar levels over the past 2-3 months. This test is essential for managing diabetes and assessing long-term glucose control. Regular monitoring of these lab tests can help healthcare providers make informed decisions about the usage of Accentrix Solution for Injection.


Additional Information

Habit FormingNo
Chemical ClassMonoclonal Antibody
Therapeutic Class-
Action ClassVascular endothelial growth factor (VEGF) inhibitor for AMD

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Content verified by

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Dr. Monie Riju Simon

MBBS - General Medicine

Last update on 11-Feb-2025